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Inhibition of SphK2 (unknown origin)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of SphK1 (unknown origin)
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Assay data:9 Active, 3 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Assay data:6 Active, 1 Activity ≤ 1 µM, 16 Tested
Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 16 Tested
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Assay data:5 Active, 1 Activity ≤ 1 µM, 16 Tested
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Assay data:11 Active, 18 Tested
SummaryCompounds, ActivePubMed Citation
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
Assay data:6 Active, 18 Tested
Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay
Inhibition of N-terminal GST-fused PKCbeta2 (1-673) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of N-terminal GST-fused PKCbeta1 (1-671) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused PKCalpha (1-672) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused sphingosine kinase 2 (1-618) expressed in baculovirus expression system assessed as inhibition of sphingosine phosphorylation after 1 hr by off-chip mobility shift assay
Assay data:9 Tested
Inhibition of N-terminal GST-fused sphingosine kinase 1 (1-384) expressed in baculovirus expression system assessed as inhibition of sphingosine phosphorylation after 1 hr by off-chip mobility shift assay
Inhibition of N-terminal GST-fused PKClota (1-587) expressed in baculovirus expression system at 3 uM after 1 hr by off-chip mobility shift assay relative to control
Assay data:3 Tested
Inhibition of N-terminal GST-fused PKCzeta (1-592) expressed in baculovirus expression system at 3 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused PKCzeta (1-592) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused PKCtheta (1-706) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused PKCeta (1-683) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
Inhibition of N-terminal GST-fused PKClota (1-587) expressed in baculovirus expression system at 30 uM after 1 hr by off-chip mobility shift assay relative to control
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