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Inhibition of pre-mRNA splicing in human HeLa nuclear extract in presence of ATP
Assay data:7 Active, 6 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Suppression of AR-V7 expression in human CWR22Rv1 cells expressing GFP measured after 3 days by FACS assay
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Displacement of biotinylated SSA from SF3b SAP155/SAP145/SAP130 complex in human HeLa cells by competition binding assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of Ac-SSA from SF3b SAP155/SAP145/SAP130 complex in human HeLa cells by competition binding assay
Assay data:2 Active, 2 Tested
Induction of subcellular localization of SAP145 in SAP145-targeting siRNA-transfected human HeLa cells after 3 days
SummaryCompounds, ActivePubMed Citation
Induction of subcellular localization of SAP155 in SAP155-targeting siRNA-transfected human HeLa cells after 3 days
Induction of truncated p27 expression in SAP130-targeting siRNA-transfected human HeLa cells
Induction of truncated p27 expression in SAP145-targeting siRNA-transfected human HeLa cells
Induction of truncated p27 expression in SAP155-targeting siRNA-transfected human HeLa cells
Induction of intron translation of Myc-tagged p27 gene in HEK293T cells at 100 ng/ml for 14 hrs by Western blotting
Induction of intron translation of HA-tagged truncated p27 gene in HEK293T cells at 100 ng/ml for 14 hrs
Induction of subcellular localization of SC35 in human HeLa cells at 100 ng/ml after 3 hrs
Induction of subcellular localization of poly(A) RNA in human HeLa cells at 100 ng/ml after 3 hrs using digoxigenin-labeled oligo-Dt probe
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of IkappaBalpha pre-mRNA splicing between exon 1 and exon 4 at 10 mg/ml after 12 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 pre-mRNA splicing between exon 1 and intron 2 at 10 mg/ml after 12 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 pre-mRNA splicing between exon 1 and exon 2 at 10 mg/ml after 12 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of beta-actin mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of beta-tubulin mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of p27 mRNA splicing at 100 ng/ml after 6 hrs by RT-PCR analysis
Binding affinity to SAP130 in human HeLa cells assessed as inhibition of FLAG-tagged beta globin splicing at 100 ng/ml after 12 hrs by RT-PCR analysis
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