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Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: OPM1_PLB cell viability assay
Assay data:896 Active, 18 Activity ≤ 1 nM, 320 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: MMM1_PLB cell viability assay
Assay data:911 Active, 7 Activity ≤ 1 nM, 657 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS12PE_JCRB cell viability assay
Assay data:722 Active, 26 Activity ≤ 1 nM, 377 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS12BM_JCRB cell viability assay
Assay data:870 Active, 12 Activity ≤ 1 nM, 424 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS27_JCRB cell viability assay
Assay data:640 Active, 26 Activity ≤ 1 nM, 465 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: H1112_PLB cell viability assay
Assay data:695 Active, 3 Activity ≤ 1 nM, 231 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JJN3_DSMZ cell viability assay
Assay data:743 Active, 23 Activity ≤ 1 nM, 495 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: INA6_PLB cell viability assay
Assay data:965 Active, 40 Activity ≤ 1 nM, 443 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: JIM3_ECACC cell viability assay
Assay data:782 Active, 10 Activity ≤ 1 nM, 239 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMM1_JCRB cell viability assay
Assay data:606 Active, 18 Activity ≤ 1 nM, 360 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: ARD_JJKsccE7 cell viability assay
Assay data:643 Active, 44 Activity ≤ 1 nM, 452 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: ARP1_JJKsccF8 cell viability assay
Assay data:662 Active, 11 Activity ≤ 1 nM, 344 Activity ≤ 1 µM, 1912 Tested
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: AMO1_DSMZ cell viability assay
Assay data:746 Active, 20 Activity ≤ 1 nM, 455 Activity ≤ 1 µM, 1912 Tested
Inhibition of GARFT (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of DHFR (unknown origin) assessed as inhibition constant
Inhibition of thymidylate synthase (unknown origin) assessed as inhibition constant
Inhibition of human thymidylate synthase expressed in Escherichia coli using 6R,S-tetrahydrofolate and dUMP as substrate by spectrophotometric analysis
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of DHFR in human KB cells expressing RFC/FRalpha/PCFT assessed as reduction in cell growth after 96 hrs in presence of folic acid by Cell-Titer Blue assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of DHFR in human KB cells expressing RFC/FRalpha/PCFT assessed as reduction in cell growth after 96 hrs by Cell-Titer Blue assay
Inhibition of DHFR in Chinese Hamster MTXRII-OuaR2-4 R2 cells expressing human PCFT assessed as reduction in cell growth after 96 hrs by Cell-Titer Blue assay
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
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