Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
FP-based equilibrium competition assay from US Patent US11312722: "Hsp90 inhibitors and uses thereof"
Assay data:111 Active, 100 Activity ≤ 1 µM, 113 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Displacement of Cy3-labeled geldanamycin from HSP90 in Cryptococcus neoformans H99 cell lysate measured after 4.5 hrs by fluorescence polarization assay
Assay data:110 Active, 93 Activity ≤ 1 µM, 113 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Displacement of Cy3-labeled geldanamycin from HSP90 in Candida albicans clinical isolate 2 cell lysate measured after 4.5 hrs by fluorescence polarization assay
Assay data:109 Active, 97 Activity ≤ 1 µM, 113 Tested
Antifungal activity against Candida albicans clinical isolate 2 assessed as fungal growth inhibition at <= 50 uM measured after 48 hrs by resazurin assay
Assay data:113 Active, 113 Tested
SummaryCompounds, ActivePubMed Citation
Antifungal activity against Cryptococcus neoformans H99 assessed as fungal growth inhibition at <= 50 uM measured after 48 hrs by resazurin assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on