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Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assay
Assay data:10 Active, 3 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vivo agonist activity at human GFP-tagged PPARalpha in transgenic zebrafish assessed as increase in GFP expression in muscle at 1.5 uM measured after 14 days by microscopy
Assay data:2 Active, 3 Tested
SummaryCompounds, ActivePubMed Citation
In vivo agonist activity at human GFP-tagged PPARalpha in transgenic zebrafish assessed as increase in GFP expression in heart at 1.5 uM measured after 14 days by microscopy
In vivo agonist activity at human GFP-tagged PPARalpha in transgenic zebrafish assessed as increase in GFP expression in yolk sac at 1.5 uM measured after 14 days by microscopy
In vivo agonist activity at human GFP-tagged PPARalpha in transgenic zebrafish assessed as increase in GFP expression in brain at 1.5 uM measured after 14 days by microscopy
Agonist activity at human PPARalpha in mouse hepatocytes assessed as induction of Pdk4 mRNA expression at 50 uM incubated for 16 hrs by quantitative real-time PCR analysis
Assay data:12 Active, 13 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at human PPARgamma in mouse 3T3-L1 cells assessed as induction of adipogenic differentiation at 25 uM measured after 11 days by Oil Red O staining analysis
Assay data:5 Active, 5 Tested
Agonist activity at human PPARgamma transfected in HEK293 cells assessed as relative luciferase unit at 50 uM measured after 16 hrs by luciferase reporter gene assay
Assay data:11 Active, 11 Tested
Agonist activity at human PPARalpha transfected in HEK293 cells assessed as relative luciferase unit at 50 uM measured after 16 hrs by luciferase reporter gene assay
Assay data:17 Active, 17 Tested
Agonist activity at human PPARdelta transfected in HEK293 cells assessed as relative luciferase unit at 50 uM measured after 16 hrs by luciferase reporter gene assay
Assay data:13 Active, 13 Tested
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