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Photocytotoxicity against mouse BALB/3T3 cells at >42 uM preincubated for 48 hrs followed by 3.3 J/cm2 UV light irradiation for 500 sec measured after 18 hrs by Alamar blue assay
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed Citation
Induction of melanin synthesis in mouse B16F10 cells at 50 uM after 48 hrs by spectrophotometric analysis relative to control
Assay data:20 Active, 25 Tested
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
SummaryCompounds, Active
Inhibition of acetylcholinesterase (unknown origin) using acetylcholine iodide as substrate preincubated for 15 mins prior to substrate addition by spectrophotometric analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of NF-KB p50 subunit/DNA interaction after 20 mins by EMSA
Assay data:7 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Mechanism based inhibition of human cytochrome P450 2A6 measured by coumarin 7-hydroxylation
Assay data:2 Active, 1 Activity ≤ 1 µM, 5 Tested
Assay data:4 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19
Assay data:1964 Active, 9 Activity ≤ 1 nM, 696 Activity ≤ 1 µM, 10320 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4
Assay data:5711 Active, 80 Activity ≤ 1 µM, 75028 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6
Assay data:1776 Active, 2 Activity ≤ 1 nM, 503 Activity ≤ 1 µM, 10320 Tested
qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4
Assay data:3571 Active, 541 Activity ≤ 1 µM, 14155 Tested
qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9
Assay data:1327 Active, 507 Activity ≤ 1 µM, 10320 Tested
p450-cyp1a2
Assay data:4446 Active, 9198 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region
Assay data:6462 Active, 59094 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region
Assay data:6249 Active, 59094 Tested
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