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Inhibition Assay of Dengue Virus from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
Assay data:8 Active, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Inhibition Assay of Zika virus from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition Assay of HCoV-229E Viruses from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition Assay of HCoV-OC43 from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
SARS-CoV-2 Plaque Assay 2 from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SARS-CoV-2 Plaque Assay 1 from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
SARS-CoV-2 Immunofluorescence Assay 2 from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
SARS-CoV-2 Immunofluorescence Assay 1 from US Patent US20240033256: "INHIBITORS OF POSITIVE STRAND RNA VIRUSES"
Growth inhibition of human MCF7 cells
Assay data:34 Active, 17 Activity ≤ 1 µM, 37 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Growth inhibition of human NCI-H460 cells
Growth inhibition of human NUGC3 cells
Assay data:34 Active, 18 Activity ≤ 1 µM, 37 Tested
Growth inhibition of human HONE1 cells
Assay data:33 Active, 11 Activity ≤ 1 µM, 37 Tested
Antiviral activity against Transmissible gastroenteritis virus infected in ST cells pre-treated 2 hrs before virus infection measured 6 hrs post virus infection by immunofluorescent assay
Assay data:29 Active, 14 Activity ≤ 1 µM, 37 Tested
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 18 hrs by nitrate/nitrite assay
Assay data:8 Active, 4 Activity ≤ 1 µM, 8 Tested
Cytotoxicity against mouse RAW264.7 cells
Assay data:2 Active, 1 Activity ≤ 1 µM, 8 Tested
Cmax in Sprague-Dawley rat at 3 mg/kg, po by HPLC-MS method
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Growth inhibition of human HepG2 cells
Assay data:29 Active, 12 Activity ≤ 1 µM, 33 Tested
Growth inhibition of human A549 cells
Assay data:31 Active, 13 Activity ≤ 1 µM, 33 Tested
Down regulation of cyclin A2 expression in human MCF7 cells incubated for 24 hrs by Western blotting
Assay data:6 Active, 6 Tested
SummaryCompounds, ActivePubMed Citation
Induction of c-Jun protein accumulation in human MCF7 cells incubated for 24 hrs by Western blotting
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