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Compound was evaluated for inhibition of human ACHE in an vitro cell free assay measured by absorbance method
Assay data:10 Active, 5 Activity ≤ 1 µM, 73 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity towards human OPRM1 in an in vitro assay with cellular components measured by scintillation counting
Assay data:117 Active, 24 Activity ≤ 1 µM, 927 Tested
Assay data:31 Active, 15 Activity ≤ 1 µM, 927 Tested
Inhibition of AChE (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method relative to control
Assay data:4 Active, 2 Activity ≤ 1 µM, 6 Tested
Binding affinity to BuChE (unknown origin) assessed as inhibition constant
Assay data:3 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to electrical eel AChE assessed as inhibition constant incubated for 20 mins by absorbance based analysis
Assay data:10 Active, 1 Activity ≤ 1 µM, 16 Tested
Binding affinity to BuChE (unknown origin) assessed as inhibition constant incubated for 30 mins by ellman's method
Assay data:2 Active, 1 Activity ≤ 1 µM, 9 Tested
Binding affinity to AChE (unknown origin) assessed as inhibition constant incubated for 30 mins by ellman's method
Assay data:1 Active, 1 Activity ≤ 1 µM, 8 Tested
Binding affinity to AChE (unknown origin) assessed as inhibition constant
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Assay data:4 Active, 5 Tested
Inhibition of BChE (unknown origin) incubated for 30 mins by Ellman's method
Assay data:10 Active, 10 Tested
Inhibition of AChE (unknown origin) incubated for 30 mins by Ellman's method
Assay data:10 Active, 1 Activity ≤ 1 µM, 10 Tested
Inhibition of human recombinant AChe using acetylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's method
Assay data:11 Active, 6 Activity ≤ 1 µM, 25 Tested
Inhibition of Equine serum BuChE using S-butyrylthiocholine iodide as a substrate and measured for 125 sec by DTNB based Ellman's method
Assay data:9 Active, 29 Tested
Inhibition of electric eel AChE using acetylcholine iodide as a substrate and measured for 125 sec by DTNB based Ellman's method
Assay data:1 Active, 24 Tested
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pre-incubated for 5 mins followed by substrate addition and measured after 6 mins by Ellman's method
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate pre-incubated for 5 mins followed by substrate addition and measured after 6 mins by Ellman's method
Assay data:2 Active, 7 Tested
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