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Inhibition of Arabidopsis thaliana SHMT using L-serine/(6S)-THF as substrate after 20 mins by methylene tetrahydrofolate dehydrogenase coupled enzyme assay
Assay data:20 Active, 1 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 23 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assay
Assay data:42 Active, 36 Activity ≤ 1 µM, 42 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antimalarial activity against Plasmodium falciparum NF54 infected in human RBC assessed as reduction in [3H]hypoxanthine incorporation preincubated for 48 hrs followed by [3H]hypoxanthine addition measured after 24 hrs by liquid scintillation counting
Assay data:53 Active, 52 Activity ≤ 1 µM, 53 Tested
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