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FP-based equilibrium competition assay from US Patent US11312722: "Hsp90 inhibitors and uses thereof"
Assay data:111 Active, 100 Activity ≤ 1 µM, 113 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Displacement of Cy3-labeled geldanamycin from HSP90 in Cryptococcus neoformans H99 cell lysate measured after 4.5 hrs by fluorescence polarization assay
Assay data:110 Active, 93 Activity ≤ 1 µM, 113 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Displacement of Cy3-labeled geldanamycin from HSP90 in Candida albicans clinical isolate 2 cell lysate measured after 4.5 hrs by fluorescence polarization assay
Assay data:109 Active, 97 Activity ≤ 1 µM, 113 Tested
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