BioAssays, activity concentration at/below 1 uM for PubChem Compound ( - PubChem BioAssay - NCBI

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Select item 19632941.

Antiproliferative activity against human taxol-resistant MCF7/ADR cells

Source:: ChEMBL

Assay data:1 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1963294

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 19616492.

Antiproliferative activity against human MDA-MB-435 cells assessed as inhibition of cell growth by SRB assay

Source:: ChEMBL

Assay data:18 Active, 16 Activity ≤ 1 µM, 21 Tested

AID:: 1961649

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19616433.

Antiproliferative activity against wild type human HeLa cells assessed as inhibition of cell growth by SRB assay

Source:: ChEMBL

Assay data:16 Active, 15 Activity ≤ 1 µM, 20 Tested

AID:: 1961643

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19616424.

Antiproliferative activity against human HeLa cells overexpressing betaIII-tubulin assessed as inhibition of cell growth by SRB assay

Source:: ChEMBL

Assay data:16 Active, 15 Activity ≤ 1 µM, 20 Tested

AID:: 1961642

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19616405.

Antiproliferative activity against wild type human SK-OV-3 cells assessed as inhibition of cell growth by SRB assay

Source:: ChEMBL

Assay data:16 Active, 14 Activity ≤ 1 µM, 20 Tested

AID:: 1961640

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19543226.

Cytotoxicity against human MDA-MB-435 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 6 Tested

AID:: 1954322

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19543217.

Cytotoxicity against human OVCAR-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:3 Active, 2 Activity ≤ 1 µM, 6 Tested

AID:: 1954321

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19543208.

Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:6 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 6 Tested

AID:: 1954320

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19535719.

Antiproliferative activity against human SK-MEL cells assessed as reduction in cell growth inhibition

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1953571

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195355810.

Antiproliferative activity against human YD-10B cells assessed as cell growth inhibition measured after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1953558

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195355711.

Antiproliferative activity against mouse EL4 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 7 Tested

AID:: 1953557

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195355612.

Antiproliferative activity against mouse P388 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 8 Tested

AID:: 1953556

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195355513.

Antiproliferative activity against human BeWo cells assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 8 Tested

AID:: 1953555

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195355414.

Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay

Source:: ChEMBL

Assay data:15 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 16 Tested

AID:: 1953554

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195354315.

Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 4 Tested

AID:: 1953543

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195354216.

Antiproliferative activity against human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1953542

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195354117.

Antiproliferative activity against human KB cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay

Source:: ChEMBL

Assay data:9 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 10 Tested

AID:: 1953541

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195353218.

Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay

Source:: ChEMBL

Assay data:9 Active, 1 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 11 Tested

AID:: 1953532

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195352019.

Cytotoxicity against African green monkey Vero cells

Source:: ChEMBL

Assay data:8 Active, 1 Activity ≤ 1 µM, 13 Tested

AID:: 1953520

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 195103920.

Antitumor activity against human MCF7 cells assessed as cell viability incubated for 48 hrs by CCK8 assay

Source:: ChEMBL

Assay data:16 Active, 2 Activity ≤ 1 µM, 29 Tested

AID:: 1951039

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (998)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (149)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,000)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (1,000)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (984)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (14)
BioAssays deposited by other experimentalists

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