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Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay
Assay data:11 Active, 2 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of PPAR-alpha (unknown origin) by SPA assay
Assay data:8 Active, 2 Activity ≤ 1 µM, 9 Tested
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway
Assay data:589 Active, 14 Activity ≤ 1 nM, 591 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Binding affinity to L-FABP low binding affinity site by titration calorimetry method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to L-FABP high binding affinity site by titration calorimetry method
Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by competitive fluorescence displacement assay
Assay data:13 Active, 6 Activity ≤ 1 µM, 20 Tested
Displacement of 1,8-ANS from eFABP by fluorescence based-assay
Assay data:9 Active, 9 Activity ≤ 1 µM, 20 Tested
Displacement of 1,8-ANS from aFABP by fluorescence based-assay
Assay data:19 Active, 19 Activity ≤ 1 µM, 20 Tested
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