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Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an RCH-ACV wild type WT cells (2C)
Assay data:2970 Active, 9 Activity ≤ 1 nM, 1016 Activity ≤ 1 µM, 10037 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Growth inhibition of human NCI-H226 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Growth inhibition of human MCF7 cells
Growth inhibition of human UACC62 cells
Growth inhibition of human LOXIMVI cells
Growth inhibition of human HCC2998 cells
Growth inhibition of human MDA-MB-231 cells
Growth inhibition of human DU145 cells
Growth inhibition of human A498 cells
Inhibition of KLF5 promoter activity in human DLD1 cells by luciferase reporter gene assay
Assay data:5 Active, 3 Activity ≤ 1 µM, 34 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Growth inhibition of rat IEC-6 cells
Growth inhibition of human SW620 cells
Growth inhibition of human HT-29 cells
Growth inhibition of human HCT116 cells
Growth inhibition of human DLD1 cells
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
Late stage counterscreen results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): Absorbance-based cell-based assay to identify modulators of cancer cell viability
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
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