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Cytotoxicity against human MES-SA cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
Cytotoxicity against human NCI-H661 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an RCH-ACV wild type WT cells (2C)
Assay data:2970 Active, 9 Activity ≤ 1 nM, 1016 Activity ≤ 1 µM, 10037 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an isogenic RCH-ACV NSD2 p.E1099K mutant (9B)
Assay data:2826 Active, 4 Activity ≤ 1 nM, 946 Activity ≤ 1 µM, 10037 Tested
Antiproliferative activity against human Hep293TT cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Assay data:11 Active, 9 Activity ≤ 1 µM, 11 Tested
Antiproliferative activity against human D283 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Assay data:11 Active, 8 Activity ≤ 1 µM, 11 Tested
Antiproliferative activity against human SJCRH30 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A673 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Assay data:11 Active, 5 Activity ≤ 1 µM, 11 Tested
Inhibition of Ebolavirus glycoprotein/matrix protein VP40 entry in human HeLa cells after 4.5 hrs beta-lactamase reporter assay
Assay data:28 Active, 6 Activity ≤ 1 µM, 28 Tested
Growth inhibition of human OVCAR8 cells after 96 hrs by trypan blue exclusion assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Cytotoxicity against doxorubicin-resistant human K562R cells incubated for 72 hrs by CellTiter 96 aqueous one solution reagent based assay
Assay data:11 Active, 2 Activity ≤ 1 µM, 15 Tested
Cytotoxicity against human K562 cells incubated for 72 hrs by CellTiter 96 aqueous one solution reagent based assay
Assay data:15 Active, 14 Activity ≤ 1 µM, 15 Tested
Cytotoxicity against human OVCAR8 cells assessed as growth inhibition after 48 hrs by SRB assay
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Cytotoxicity against human K562 cells after 72 hrs by resazurin-based fluorimetric assay
Cytotoxicity against human HCT116 cells after 72 hrs by resazurin-based fluorimetric assay
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