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Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an RCH-ACV wild type WT cells (2C)
Assay data:2970 Active, 9 Activity ≤ 1 nM, 1016 Activity ≤ 1 µM, 10037 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an isogenic RCH-ACV NSD2 p.E1099K mutant (9B)
Assay data:2826 Active, 4 Activity ≤ 1 nM, 946 Activity ≤ 1 µM, 10037 Tested
Primary qHTS for inhibitors of La Crosse Virus (LACV) - induced cell death in SH-SY5Y cells
Assay data:30 Active, 282 Activity ≤ 1 µM, 3830 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway
Assay data:1356 Active, 2 Activity ≤ 1 nM, 487 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Increased HeLa cells with 4N DNA content-IC50
Assay data:19 Active, 19 Activity ≤ 1 µM, 184 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Increased chromatin condensation in HeLa cells-IC50
Assay data:31 Active, 23 Activity ≤ 1 µM, 184 Tested
Increased HeLa cells with 2N DNA content-IC50
Assay data:30 Active, 25 Activity ≤ 1 µM, 182 Tested
Decreased HeLa cell count-IC50
Assay data:74 Active, 1 Activity ≤ 1 nM, 56 Activity ≤ 1 µM, 181 Tested
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50
Assay data:138 Active, 2 Activity ≤ 1 nM, 64 Activity ≤ 1 µM, 369 Tested
alkaline phosphatase stimulation in WNT3A conditioned C2C12 cells-IC50
Assay data:48 Active, 1 Activity ≤ 1 nM, 35 Activity ≤ 1 µM, 97 Tested
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-IC50
Assay data:47 Active, 33 Activity ≤ 1 µM, 98 Tested
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