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Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured after 24 hrs by luciferase reporter gene assay based Schild plot analysis
Assay data:4 Active, 4 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase reporter gene assay
Assay data:6 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 7 Tested
Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells incubated for 1 hr by liquid scintillation counting method
Assay data:7 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 7 Tested
Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells incubated for 1 hr by liquid scintillation counting method
qHTS assay to identify small molecule antagonists of the estrogen receptor beta (ER-beta) signaling pathway
Assay data:464 Active, 1 Activity ≤ 1 nM, 65 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule antagonists of the constitutive androstane receptor (CAR) signaling pathway: Summary
Assay data:196 Active, 134 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the constitutive androstane receptor (CAR) signaling pathway
Assay data:575 Active, 6 Activity ≤ 1 nM, 184 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary
Assay data:589 Active, 16 Activity ≤ 1 nM, 99 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway
Assay data:146 Active, 1 Activity ≤ 1 nM, 175 Activity ≤ 1 µM, 9305 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line
Assay data:1084 Active, 8 Activity ≤ 1 nM, 330 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway
Assay data:589 Active, 14 Activity ≤ 1 nM, 591 Activity ≤ 1 µM, 10486 Tested
qHTS assay for small molecule agonists of estrogen receptor alpha signaling
Assay data:88 Active, 2 Activity ≤ 1 nM, 43 Activity ≤ 1 µM, 2858 Tested
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