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Kinase Inhibition SPA Assay from Article 10.1016/s0960-894x(03)00645-0: "6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)."
Assay data:25 Active, 3 Activity ≤ 1 nM, 24 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human GSK3alpha
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of GSK3
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Assay data:77 Active, 7 Activity ≤ 1 nM, 71 Activity ≤ 1 µM, 77 Tested
Inhibition of recombinant GSK3-beta
Assay data:146 Active, 3 Activity ≤ 1 nM, 135 Activity ≤ 1 µM, 151 Tested
Inhibitory concentration against glycogen synthase kinase-3 alpha
Assay data:28 Active, 1 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 38 Tested
Inhibitory activity to human glycogen synthase kinase-3 alpha (GSK-3alpha) was determined
Assay data:23 Active, 3 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 24 Tested
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