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Induction of apoptosis in human MCF7 cells upto 100 uM by microplate reader analysis
Assay data:1 Tested
SummaryPubMed Citation
Induction of apoptosis in human HCT-116 cells upto 100 uM by microplate reader analysis
Immunostimulatory activity in mouse C57 spleen B cells in assessed as fold increase at 0.1 to 10 uM incubated for 48 hrs by flow cytometry analysis
Immunostimulatory activity in mouse C57 spleen CD3+ T cells in assessed as fold increase at 0.1 to 10 uM incubated for 48 hrs by flow cytometry analysis
Activation of NF-kappaB signalling in HEK-Blue hTLR2 cells at 10 uM in presence of triptolide
SummaryPubMed CitationRelated BioAssays by Target
Induction of nitric oxide release in mouse RAW264.7 cells at 0.01 to 10 uM incubated for 24 hrs by Griess reagent based assay
Induction of IL-6 secretion in wild-type C57BL/6 mouse peritoneal macrophages at 0.01 to 10 uM incubated for 24 hrs by ELISA method
Induction of TNFalpha secretion in wild-type C57BL/6 mouse peritoneal macrophages at 0.01 to 10 uM incubated for 24 hrs by ELISA method
Induction of IL-6 secretion in TLR2-/- C57BL/6 mouse peritoneal macrophages at 0.01 to 10 uM incubated for 24 hrs by ELISA method
Induction of TNFalpha secretion in TLR2-/- C57BL/6 mouse peritoneal macrophages at 0.01 to 10 uM incubated for 24 hrs by ELISA method
Induction of JNK phosphorylation in human PMA-differentiated THP-1 cells at 10 uM incubated for 2 hrs by Western blot analysis
Induction of ERK phosphorylation in human PMA-differentiated THP-1 cells at 10 uM incubated for 2 hrs by Western blot analysis
Upregulation of MyD88 expression in human PMA-differentiated THP-1 cells in presence of T6167923 at 10 uM incubated for 2 hrs by western blot analysis
Upregulation of TLR6 expression in human THP-1 cells at 20 uM by immunoprecipitation method
Induction of TNFalpha secretion in TLR2 knock down human THP-1 cells at 20 to 40 uM incubated for 24 hrs by ELISA method
Assay data:2 Tested
Agonist activity at TLR6 in HEK-Blue hTLR2 cells at 0.2 uM incubated for 24 hrs in presence of anti-hTLR6-IgA antibodies measured by Quanti-Blue based SEAP assay
Agonist activity at TLR8 in HEK-Blue hTLR8 cells at 0.1 to 100 uM incubated for 24 hrs by Quanti-Blue based SEAP assay
Agonist activity at TLR7 in HEK-Blue hTLR7 cells at 0.1 to 100 uM incubated for 24 hrs by Quanti-Blue based SEAP assay
Agonist activity at TLR5 in HEK-Blue hTLR5 cells at 0.1 to 100 uM incubated for 24 hrs by Quanti-Blue based SEAP assay
Agonist activity at TLR4 in HEK-Blue hTLR4 cells at 0.1 to 100 uM incubated for 24 hrs by Quanti-Blue based SEAP assay
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