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Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay.
Assay data:1241 Active, 184 Activity ≤ 1 µM, 1545 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against the NCATS MIPE library collection: KMS12BM_JCRB cell viability assay
Assay data:870 Active, 12 Activity ≤ 1 nM, 424 Activity ≤ 1 µM, 1912 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary redox qHTS assay for identification of artifact compounds.
Assay data:19 Active, 16 Activity ≤ 1 µM, 5098 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Primary Nanoluciferase (NLuc) qHTS assay for identification of artifact compounds.
Assay data:37 Active, 2 Activity ≤ 1 µM, 5098 Tested
Primary fluorescence-based thiol-reactive (MSTI) qHTS assay for identification of artifact compounds.
Assay data:494 Active, 184 Activity ≤ 1 µM, 5098 Tested
Primary firefly luciferase (FLuc) qHTS assay for identification of artifact compounds.
Assay data:75 Active, 14 Activity ≤ 1 µM, 5098 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Protac activity at VHL/AKT in human BT-474 cells assessed as inhibition of downstream signalling by measuring reduction in PRAS40 phosphorylation at T246 residue at 1 uM measured after 24 hrs Western blot analysis
Assay data:2 Tested
SummaryPubMed Citation
Protac activity at VHL/AKT in human BT-474 cells assessed as reduction in total AKT protein level at 1 uM measured after 24 hrs by Western blot analysis
Assay data:4 Active, 6 Tested
SummaryCompounds, ActivePubMed Citation
NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration
Assay data:3073 Active, 74254 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration
Assay data:5131 Active, 77082 Tested
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell Lung cell line, single concentration
Assay data:4318 Active, 77515 Tested
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration
Assay data:3653 Active, 76840 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Non-Small Cell Lung cell line, single concentration
Assay data:5608 Active, 76570 Tested
NCI human tumor cell line growth inhibition assay. Data for the T-47D Non-Small Cell Lung cell line, single concentration
Assay data:3353 Active, 74196 Tested
NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Non-Small Cell Lung cell line, single concentration
Assay data:3002 Active, 76488 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Non-Small Cell Lung cell line, single concentration
Assay data:3404 Active, 76205 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-3 Non-Small Cell Lung cell line, single concentration
Assay data:5012 Active, 76370 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-4 Non-Small Cell Lung cell line, single concentration
Assay data:2494 Active, 74525 Tested
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