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Inhibition of SARS-CoV-2-induced cytopathy was measured 4 days after infection of EGFP-labeled Green monkey Vero cells by fluorescence imaging.
Assay data:19 Active, 7 Activity ≤ 1 µM, 134 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
High-throughput screening primary assay to identify small molecule activators of human guanylyl cyclase B (GC-B) receptor activity
Assay data:399 Active, 370620 Tested
SummaryCompounds, Active
SARS-CoV PLpro Inhibition Assay from Article 10.3109/14756366.2012.753591: "Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia."
Assay data:4 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
NCATS anti-infectives library activity on HEK293 viability as a counter-qHTS vs the C. elegans viability qHTS
Assay data:25 Active, 678 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
High-throughput screening primary assay to identify small molecule activators of human GC-A enzyme activity
Assay data:519 Active, 370620 Tested
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2
Assay data:6069 Active, 5332 Activity ≤ 1 µM, 575118 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
Cell-based high-throughput assay to identify small molecules that inhibit phospholipid biosynthesis in animal cells 2: screen of the Analyticon library.
Assay data:3 Active, 495 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
qHTS Assay for Foot and Mouth Disease Virus Antivirals: Primary Screen against the MLPCN compound library
Assay data:1964 Active, 408697 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS for Suppressors of FUS Proteinopathy: Primary screen using FUS-linked yeast assay
Assay data:932 Active, 388864 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal
Assay data:316 Active, 7162 Tested
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): Viability assay - alamar blue signal for LCMV Primary Screen
Assay data:468 Active, 7162 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen
Assay data:588 Active, 7162 Tested
qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal
Assay data:239 Active, 7162 Tested
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1
Assay data:13449 Active, 399619 Tested
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the parental adenocarcinoma cell KB-3-1
Assay data:5540 Active, 399561 Tested
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