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The drug is tested on Bacteroides fragilis strain: ATCC43859 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:202 Tested
Summary
The drug is tested on Bacteroides fragilis strain: HMW615 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:205 Tested
The drug is tested on Bacteroides fragilis strain: HMW610 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:216 Tested
The drug is tested on Bacteroides fragilis strain: DS-208 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:235 Tested
The drug is tested on Bacteroides fragilis strain: T(B)9 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:217 Tested
The drug is tested on Bacteroides fragilis strain: 3397 (T10) for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:229 Tested
The drug is tested on Bacteroides fragilis strain: NCTC 9343 for biotransformation. The drug concentrations were measured before and after a 12-h incubation by liquid-chromatography-coupled mass spectrometry (LC?MS)
Assay data:234 Tested
Antibacterial activity against metronidazole-resistant Bacteroides fragilis MMX 3387
Assay data:4 Tested
SummaryPubMed Citation
Antibacterial activity against Bacteroides fragilis ATCC 25285
Antibacterial activity against Bacteroides fragilis ATCC 25285 assessed as inhibition of bacterial growth by CLSI based agar dilution susceptibility analysis
Assay data:7 Tested
Antibacterial activity against Bacteroides fragilis PA-2-II incubated for 18 hrs by microbroth dilution method
Assay data:1 Tested
Substrate activity at recombinant His-tagged Bacteroides fragilis alpha L-fucosidase expressed in Escherichia coli BL21(DE3) assessed as de-fucosylation of N-glycan at 5 mg/ml measured after 21 hrs by LC/MS analysis
Substrate activity at recombinant His-tagged Bacteroides fragilis alpha L-fucosidase expressed in Escherichia coli BL21(DE3) assessed as de-fucosylation of N-glycan at 5 mg/ml measured after 7 hrs by LC/MS analysis
Substrate activity at recombinant His-tagged Bacteroides fragilis alpha L-fucosidase expressed in Escherichia coli BL21(DE3) assessed as compound hydrolysis at 5 mg/ml measured after 60 mins by LC/MS analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Substrate activity at recombinant His-tagged Bacteroides fragilis alpha L-fucosidase expressed in Escherichia coli BL21(DE3) assessed as formation of p-nitrophenyl products at 5 mM measured by UV spectrometer assay
Antibacterial activity against gut Bacteroides fragilis HM-709 assessed as reduction in bacterial growth measured after 48 hrs by CLSI based broth microdilution method
Antimicrobial activity against Bacteroides fragilis ATCC 25285 assessed as reduction in bacterial growth at 0.195 to 100 ug/ml by disk diffusion method
Antibacterial activity against Bacteroides fragilis HM-709 assessed as reduction in microbial growth after 48 hrs by broth microdilution method
Assay data:1 Active, 4 Tested
Antibacterial activity against Bacteroides fragilis HM-711 assessed as reduction in microbial growth after 48 hrs by broth microdilution method
Assay data:2 Active, 4 Tested
Antibacterial activity against Bacteroides fragilis ATCC 25285 by CLSI method
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