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Effect on response rate in squirrel monkey at 0.001 mg/kg, im
Assay data:1 Tested
SummaryPubMed Citation
Effect on response rate in squirrel monkey at 0.003 mg/kg, im
Induction of CB1-related discriminative stimulus effect in squirrel monkey assessed as time required for 50% loss of full effect at 0.001 mg/kg, im
Induction of CB1-related discriminative stimulus effect in squirrel monkey at 0.003 mg/kg, im measured at 36 hrs
Induction of CB1-related discriminative stimulus effect in squirrel monkey at 0.001 mg/kg, im after 4 to 16 hrs
Induction of CB1-related discriminative stimulus effect in squirrel monkey at 0.003 mg/kg, im measured after 24 hrs
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Induction of CB1-related discriminative stimulus effect in squirrel monkey assessed as time required for 50% loss of full effect at 0.003 mg/kg, im
Induction of CB1-related discriminative stimulus effect in squirrel monkey at 0.003 mg/kg, im measured within 15 mins
Induction of CB1-related discriminative stimulus effect in squirrel monkey at 0.001 mg/kg, im after 1 hr
Toxicity in normotensive squirrel monkey model assessed as emesis at 100 mg/kg, po qd measured on day 2
Toxicity in normotensive squirrel monkey model assessed as emesis at 30 mg/kg, po qd measured on day 1
Toxicity in normotensive squirrel monkey model at 100 mg/kg, po qd measured on day 3
Toxicity in normotensive squirrel monkey model assessed as change in heart rate at 100 mg/kg, po qd measured on day 4
Toxicity in normotensive squirrel monkey model assessed as change in heart rate at 100 mg/kg, po qd measured on day 3
Assay data:2 Tested
Toxicity in normotensive squirrel monkey model assessed as change in heart rate at 100 mg/kg, po qd measured on day 1
Toxicity in normotensive squirrel monkey model assessed as change in heart rate at 100 mg/kg, po qd measured on day 2
Assay data:3 Tested
Toxicity in normotensive squirrel monkey model assessed as change in heart rate at 30 mg/kg, po qd measured on day 1
Antihypertensive activity in normotensive squirrel monkey model assessed as decrease in systolic blood pressure at 100 mg/kg, po qd measured on day 4 by sphygmomanometry
Antihypertensive activity in normotensive squirrel monkey model assessed as decrease in systolic blood pressure at 100 mg/kg, po qd measured on day 3 by sphygmomanometry
Antihypertensive activity in normotensive squirrel monkey model assessed as decrease in systolic blood pressure at 100 mg/kg, po qd measured on day 1 by sphygmomanometry
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