PubChem BioAssay Links for Taxonomy (Select 9913) - PubChem BioAssay - NCBI

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Items: 1 to 20 of 7646

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Select item 19624601.

3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE6)

Source:: ChEMBL

Protein Targets:: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'; ...
Total:: 6

Assay data:1 Tested

AID:: 1962460

Summary Related BioAssays by Target

Select item 19624552.

3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE1)

Source:: ChEMBL

Protein Targets:: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; ...
Total:: 3

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1962455

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19616463.

Inhibition of bovine brain tubulin assembly

Source:: ChEMBL

Protein Targets:: Similar to alpha-tubulin isoform 1; ...
Total:: 3

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1961646

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19572684.

Inhibition of bovine lens ALR2

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1957268

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19496525.

Binding affinity to bovine 5-HT1B

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949652

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19495636.

Inhibition of calf thymus PARP-2

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949563

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19495627.

Inhibition of calf thymus PARP-1

Source:: ChEMBL

Protein Target:: Poly [ADP-ribose] polymerase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949562

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19469178.

Inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycoside as substrate by spectrometric method

Source:: ChEMBL

Assay data:1 Tested

AID:: 1946917

Summary PubMed Citation

Select item 19469149.

Inhibition of bovine liver beta-glucosidase using p-nitrophenyl glycoside as substrate by spectrometric method

Source:: ChEMBL

Assay data:1 Tested

AID:: 1946914

Summary PubMed Citation

Select item 194371310.

Antagonist activity at bovine lung membrane adrenergic beta-2 receptor

Source:: ChEMBL

Protein Target:: Beta-2 adrenergic receptor

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1943713

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194371111.

Binding affinity to bovine lung membrane adrenergic beta-2 receptor

Source:: ChEMBL

Protein Target:: Beta-2 adrenergic receptor

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1943711

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194294312.

Inhibition of chymotrypsin in bovine pancreas using Suc-AAPF-AMC as substrate by fluorescence based analysis

Source:: ChEMBL

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1942943

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194278813.

Inhibition of ALR2 in calf lens using D,L-glyceraldehyde as substrate in presence of NADPH by spectrophotometric assay

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 1942788

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194260014.

Inhibition of bovine brain tubulin polymerization incubated for 20 mins in presence of GTP

Source:: ChEMBL

Protein Targets:: Similar to alpha-tubulin isoform 1; ...
Total:: 3

Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested

AID:: 1942600

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194162715.

Antitubulin activity against bovine brain tubulin polymerization by spectrophotometric method

Source:: ChEMBL

Protein Targets:: Similar to alpha-tubulin isoform 1; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941627

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194111116.

Inhibition of bovine brain farnesyltransferase

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941111

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194103217.

Inhibition of Calf ALR2 in presence of NADPH by UV spectrophotometric analysis

Source:: ChEMBL

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1941032

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194103118.

Inhibition of bovine kidney ALR1 in presence of NADPH by UV spectrophotometric analysis

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1941031

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194103019.

Inhibition of calf lens ALR2 using glyceraldehyde as substrate incubated for 5 mins in presence of NADPH by UV-spectrophotometric analysis

Source:: ChEMBL

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1941030

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 193958520.

Inhibition of bovine serum albumin denaturation incubated for 15 mins

Source:: ChEMBL

Protein Target:: Albumin

Assay data:1 Tested

AID:: 1939585

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (373)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (2,836)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (217)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,299)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (3)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (2,443)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (18)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (7,569)
BioAssays extracted from the literature
NIH MLP (19)
BioAssays deposited by the NIH Molecular Libraries Program
Other (58)
BioAssays deposited by other experimentalists

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