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Late stage results for the probe development effort to identify inhibitors of Plasmodium falciparum gametocytes: Luminescence-based cell-based high throughput dose response assay to identify inhibitors of viability of late stage Plasmodium falciparum gametocytes
Assay data:13 Tested
SummaryPubMed Citation
Luminescence-based cell-based high throughput dose response assay to identify inhibitors of viability of late stage Plasmodium falciparum gametocytes
Assay data:2 Active, 244 Tested
SummaryCompounds, ActivePubMed Citation
Dose response counterscreen for inhibitors of viability of late stage Plasmodium falciparum gametocytes: Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to Jurkat human T lymphocyte cells.
Assay data:7 Active, 1 Activity ≤ 1 µM, 244 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (M17LAP): radiolabel-based cell-based dose response assay to identify compounds that inhibit P. falciparum growth in RBCs Set 2
Assay data:7 Active, 17 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based dose response assay to identify compounds that inhibit P. falciparum growth in RBCs, Set 2.
Assay data:32 Active, 9 Activity ≤ 1 µM, 35 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen
Assay data:738 Active, 2 Activity ≤ 1 nM, 2507 Activity ≤ 1 µM, 364447 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_DryPowder_Activity
Assay data:5 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity
Assay data:222 Active, 23 Activity ≤ 1 µM, 278 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_CherryPick_Activity
Assay data:5 Active, 20 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with Dd2 at 96hr using Flow Cytometry
Assay data:36 Active, 9 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with Dd2 at 48 hr using Flow Cytometry
Assay data:27 Active, 1 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with 3D7 at 96 hr using Flow Cytometry
Assay data:42 Active, 10 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation at 96 hr
Assay data:37 Active, 13 Activity ≤ 1 µM, 44 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with 3D7 at 48 hr using Flow Cytometry
Assay data:24 Active, 1 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation at 48 hr
Assay data:17 Active, 4 Activity ≤ 1 µM, 44 Tested
In vivo-based yeast HTS counterscreen to detect compounds rescuing yeast growth/survival of Saccharomyces cerevisiae SKN7-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-02_Inhibitor_Dose_CherryPick_Activity
Assay data:351 Active, 54 Activity ≤ 1 µM, 828 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) (3)
Assay data:17 Active, 46 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (2)
Assay data:20 Active, 46 Tested
Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3)
Counterscreen for inhibitors of PFM1 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) (3)
Assay data:30 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same Project
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