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Dose response counterscreen for inhibitors of viability of late stage Plasmodium falciparum gametocytes: Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to Jurkat human T lymphocyte cells.
Assay data:7 Active, 1 Activity ≤ 1 µM, 244 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based dose response assay to identify compounds that inhibit P. falciparum growth in RBCs, Set 2.
Assay data:32 Active, 9 Activity ≤ 1 µM, 35 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen
Assay data:738 Active, 2 Activity ≤ 1 nM, 2507 Activity ≤ 1 µM, 364447 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_DryPowder_Activity
Assay data:5 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity
Assay data:222 Active, 23 Activity ≤ 1 µM, 278 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with Dd2 at 96hr using Flow Cytometry
Assay data:36 Active, 9 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with Dd2 at 48 hr using Flow Cytometry
Assay data:27 Active, 1 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with 3D7 at 96 hr using Flow Cytometry
Assay data:42 Active, 10 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation at 96 hr
Assay data:37 Active, 13 Activity ≤ 1 µM, 44 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation with 3D7 at 48 hr using Flow Cytometry
Assay data:24 Active, 1 Activity ≤ 1 µM, 42 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid: Hit Validation at 48 hr
Assay data:17 Active, 4 Activity ≤ 1 µM, 44 Tested
In vivo-based yeast HTS counterscreen to detect compounds rescuing yeast growth/survival of Saccharomyces cerevisiae SKN7-mediated toxicity Measured in Whole Organism System Using Plate Reader - 2120-02_Inhibitor_Dose_CherryPick_Activity
Assay data:351 Active, 54 Activity ≤ 1 µM, 828 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH - Set 3
Assay data:12 Active, 1 Activity ≤ 1 µM, 17 Tested
SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 4
Assay data:4 Active, 1 Activity ≤ 1 µM, 17 Tested
SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 3
Assay data:13 Active, 1 Activity ≤ 1 µM, 24 Tested
Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) (3)
Assay data:4 Active, 1 Activity ≤ 1 µM, 14 Tested
A cell-based HTS for delayed death inhibitors of the malarial parasite plastid Measured in Microorganism System Using Plate Reader - 2126-02_Inhibitor_Dose_DryPowder_Activity
Assay data:9 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 10 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation.
Assay data:53 Active, 35 Activity ≤ 1 µM, 54 Tested
Quantitative high throughput screen to test activity of anti-malarial compounds in the Dd2 strain of Plasmodium Falciparum
Assay data:53 Active, 26 Activity ≤ 1 µM, 54 Tested
Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation.
Assay data:53 Active, 2 Activity ≤ 1 nM, 41 Activity ≤ 1 µM, 54 Tested
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