txid33630[Organism:exp] AND (pcassay_pcassay_otherexperimentalists[fil - PubChem BioAssay - NCBI

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Select item 19631151.

Re-testing in dose-response curve in Dd2 pLDH assay, at 72h

Source:: ChEMBL

Assay data:15 Active, 4 Activity ≤ 1 µM, 15 Tested

AID:: 1963115

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 17861162.

Re-testing in dose-response curve in 3D7 pLDH assay, at 72h

Source:: ChEMBL

Assay data:74 Active, 47 Activity ≤ 1 µM, 84 Tested

AID:: 1786116

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 17861143.

Hit confirmation in dose-response curve in NF54 nanoGlo assay, at 12h

Source:: ChEMBL

Assay data:415 Active, 46 Activity ≤ 1 µM, 647 Tested

AID:: 1786114

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 17861134.

Hit confirmation in dose-response curve in Dd2 pLDH assay, at 72h

Source:: ChEMBL

Assay data:532 Active, 72 Activity ≤ 1 µM, 647 Tested

AID:: 1786113

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 17861125.

Hit confirmation in dose-response curve in NF54 pLDH assay, at 72h

Source:: ChEMBL

Assay data:548 Active, 70 Activity ≤ 1 µM, 647 Tested

AID:: 1786112

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 17861116.

Hit confirmation in dose-response curve in NF54 nanoGlo assay, at 72h

Source:: ChEMBL

Assay data:633 Active, 123 Activity ≤ 1 µM, 647 Tested

AID:: 1786111

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 17861107.

Confirmatory screen in NF54 pLDH assay, in single point, at 2uM, 72h

Source:: ChEMBL

Assay data:4815 Tested

AID:: 1786110

Select item 17861098.

Confirmatory screen in NF54 nanoGlo assay, in single point, at 2uM, 72h

Source:: ChEMBL

Assay data:4815 Tested

AID:: 1786109

Select item 17861089.

Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h

Source:: ChEMBL

Assay data:147432 Tested

AID:: 1786108

Select item 167116810.

In vitro enzyme assay to detect hydrolysis of chlorophenol red-beta-D-galactopyranosidase directly proportional to the number of Toxoplasma stably expressing beta-galactosidase

Source:: ChEMBL

Assay data:102 Active, 8 Activity ≤ 1 µM, 84955 Tested

AID:: 1671168

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134062911.

Antiparasitic activity against chloroquine-resistant/verapamil-sensitive Plasmodium falciparum Dd2 assessed as growth inhibition in presence of chloroquine

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1340629

Summary Compounds, Active

Select item 134062812.

Potentiation of chloroquine-induced anitiparasitic activity in chloroquine-resistant/verapamil-sensitive Plasmodium falciparum Dd2 assessed as decrease in chloroquine IC50 relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1340628

Select item 134062613.

Potentiation of chloroquine-induced anitiparasitic activity in chloroquine-resistant/verapamil-sensitive Plasmodium falciparum Dd2 assessed as chloroquine IC50 (Rvb = 150 nM)

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1340626

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134062414.

Antiparasitic activity against chloroquine-resistant/verapamil-sensitive Plasmodium falciparum VS/1

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1340624

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134062115.

Antiparasitic activity against chloroquine-sensitive Plasmodium falciparum HB3

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 4 Tested

AID:: 1340621

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134062016.

Antiparasitic activity against chloroquine-sensitive Plasmodium falciparum 3D7

Source:: ChEMBL

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1340620

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134061917.

Antiparasitic activity against chloroquine-resistant/verapamil-sensitive Plasmodium falciparum FCR-3/Gambia

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1340619

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134061818.

Antiparasitic activity against chloroquine-resistant/verapamil-sensitive Plasmodium falciparum Dd2

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1340618

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134061719.

Antiparasitic activity against chloroquine-resistant/verapamil-insensitive Plasmodium falciparum 7G8

Source:: ChEMBL

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1340617

Summary Compounds, Active Compounds, activity ≤ 1 µM

Select item 134061620.

Antiparasitic activity against Plasmodium falciparum 3D7 assessed as growth inhibition after 56 hrs

Source:: ChEMBL

Assay data:3 Active, 3 Tested

AID:: 1340616

Summary Compounds, Active

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Proteins (17)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (112)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (29)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (114)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (121)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (3)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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