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Select item 94925411.

Divergent genomic trajectories predate the origin of animals and fungi

Eduard Ocaña-Pallarès, Tom A. Williams, David López-Escardó, Alicia S. Arroyo, Jananan S. Pathmanathan, Eric Bapteste, Denis V. Tikhonenkov, Patrick J. Keeling, Gergely J. Szöllősi, Iñaki Ruiz-Trillo

Nature. 2022; 609(7928): 747–753. Published online 2022 Aug 24. doi: 10.1038/s41586-022-05110-4

PMCID:: PMC9492541

Abstract Article PDF–33M

Select item 58764022.

Src signaling in a low-complexity unicellular kinome

Hiroshi Suga, W. Todd Miller

Sci Rep. 2018; 8: 5362. Published online 2018 Mar 29. doi: 10.1038/s41598-018-23721-8

PMCID:: PMC5876402

Abstract Article PDF–3.1M

Select item 56829623.

Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase

Barbara Taskinen, Evandro Ferrada, Douglas M. Fowler

J Biol Chem. 2017 Nov 10; 292(45): 18518–18529. Published online 2017 Sep 22. doi: 10.1074/jbc.M117.811174

PMCID:: PMC5682962

Abstract Article PDF–3.0M

Select item 47397634.

Complex transcriptional regulation and independent evolution of fungal-like traits in a relative of animals

Alex de Mendoza, Hiroshi Suga, Jon Permanyer, Manuel Irimia, Iñaki Ruiz-Trillo

eLife. 2015; 4: e08904. Published online 2015 Oct 14. doi: 10.7554/eLife.08904

PMCID:: PMC4739763

Abstract Article PDF–3.9M

Select item 45388235.

The ancestor of modern Holozoa acquired the CCA-adding enzyme from Alphaproteobacteria by horizontal gene transfer

Heike Betat, Tobias Mede, Sandy Tretbar, Lydia Steiner, Peter F. Stadler, Mario Mörl, Sonja J. Prohaska

Nucleic Acids Res. 2015 Aug 18; 43(14): 6739–6746. Published online 2015 Jun 27. doi: 10.1093/nar/gkv631

PMCID:: PMC4538823

Abstract Article PDF–237K

Select item 45008356.

Diversity and distribution of unicellular opisthokonts along the European coast analyzed using high-throughput sequencing

Javier del Campo, Diego Mallo, Ramon Massana, Colomban de Vargas, Thomas A. Richards, Iñaki Ruiz-Trillo

Environ Microbiol. Author manuscript; available in PMC 2015 Sep 10.

Published in final edited form as: Environ Microbiol. 2015 Sep; 17(9): 3195–3207. Published online 2015 Feb 14. doi: 10.1111/1462-2920.12759

PMCID:: PMC4500835

Abstract Article PDF–1.5M

Select item 43271567.

The Eukaryotic Ancestor Had a Complex Ubiquitin Signaling System of Archaeal Origin

Xavier Grau-Bové, Arnau Sebé-Pedrós, Iñaki Ruiz-Trillo

Mol Biol Evol. 2015 Mar; 32(3): 726–739. Published online 2014 Dec 17. doi: 10.1093/molbev/msu334

PMCID:: PMC4327156

Abstract Article PDF–1.1M

Select item 39715898.

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity

Alex de Mendoza, Arnau Sebé-Pedrós, Iñaki Ruiz-Trillo

Genome Biol Evol. 2014 Mar; 6(3): 606–619. Published online 2014 Feb 23. doi: 10.1093/gbe/evu038

PMCID:: PMC3971589

Abstract Article PDF–736K

Select item 39420369.

Evolution and Classification of Myosins, a Paneukaryotic Whole-Genome Approach

Arnau Sebé-Pedrós, Xavier Grau-Bové, Thomas A. Richards, Iñaki Ruiz-Trillo

Genome Biol Evol. 2014 Feb; 6(2): 290–305. Published online 2014 Jan 18. doi: 10.1093/gbe/evu013

PMCID:: PMC3942036

Abstract Article PDF–581K

Select item 999803510.

Increased Sampling and Intracomplex Homologies Favor Vertical Over Horizontal Inheritance of the Dam1 Complex

Laura E van Rooijen, Eelco C Tromer, Jolien J E van Hooff, Geert J P L Kops, Berend Snel

Genome Biol Evol. 2023 Mar; 15(3): evad017. Published online 2023 Feb 15. doi: 10.1093/gbe/evad017

Correction in:: Genome Biol Evol. 2024 Apr; 16(4): evae072.

PMCID:: PMC9998035

Abstract Article PDF–5.9M

Select item 984832011.

Structural and evolutionary insights into astacin metallopeptidases

F. Xavier Gomis-Rüth, Walter Stöcker

Front Mol Biosci. 2022; 9: 1080836. Published online 2023 Jan 4. doi: 10.3389/fmolb.2022.1080836

PMCID:: PMC9848320

Abstract Article PDF–5.0M

Select item 685584112.

A unicellular relative of animals generates a layer of polarized cells by actomyosin-dependent cellularization

Omaya Dudin, Andrej Ondracka, Xavier Grau-Bové, Arthur AB Haraldsen, Atsushi Toyoda, Hiroshi Suga, Jon Bråte, Iñaki Ruiz-Trillo

eLife. 2019; 8: e49801. Published online 2019 Oct 28. doi: 10.7554/eLife.49801

Correction in:: eLife. 2020; 9: e60055.

PMCID:: PMC6855841

Abstract Article PDF–4.3M

Select item 620697613.

Unicellular Origin of the Animal MicroRNA Machinery

Jon Bråte, Ralf S. Neumann, Bastian Fromm, Arthur A.B. Haraldsen, James E. Tarver, Hiroshi Suga, Philip C.J. Donoghue, Kevin J. Peterson, Iñaki Ruiz-Trillo, Paul E. Grini, Kamran Shalchian-Tabrizi

Curr Biol. 2018 Oct 22; 28(20): 3288–3295.e5. doi: 10.1016/j.cub.2018.08.018