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Select item 102183541.

nc886, an RNA Polymerase III-Transcribed Noncoding RNA Whose Expression Is Dynamic and Regulated by Intriguing Mechanisms

Yeon-Su Lee, Yong Sun Lee

Int J Mol Sci. 2023 May; 24(10): 8533. Published online 2023 May 10. doi: 10.3390/ijms24108533

PMCID:: PMC10218354

Abstract Article PDF–1.3M

Select item 87056762.

nc886, a Non-Coding RNA, Is a New Biomarker and Epigenetic Mediator of Cellular Senescence in Fibroblasts

Yuna Kim, Hyanggi Ji, Eunae Cho, Nok-Hyun Park, Kyeonghwan Hwang, Wonseok Park, Kwang-Soo Lee, Deokhoon Park, Eunsun Jung

Int J Mol Sci. 2021 Dec; 22(24): 13673. Published online 2021 Dec 20. doi: 10.3390/ijms222413673

PMCID:: PMC8705676

Abstract Article PDF–1.9M

Select item 82723123.

Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Young-Ah You, Eun Jin Kwon, Han-Sung Hwang, Suk-Joo Choi, Sae Kyung Choi, Young Ju Kim

BMC Genomics. 2021; 22: 528. Published online 2021 Jul 10. doi: 10.1186/s12864-021-07865-y

PMCID:: PMC8272312

Abstract Article PDF–770K

Select item 79615044.

VTRNA2-1: Genetic Variation, Heritable Methylation and Disease Association

Pierre-Antoine Dugué, Chenglong Yu, Timothy McKay, Ee Ming Wong, Jihoon Eric Joo, Helen Tsimiklis, Fleur Hammet, Maryam Mahmoodi, Derrick Theys, kConFab, John L. Hopper, Graham G. Giles, Roger L. Milne, Jason A. Steen, James G. Dowty, Tu Nguyen-Dumont, Melissa C. Southey

Int J Mol Sci. 2021 Mar; 22(5): 2535. Published online 2021 Mar 3. doi: 10.3390/ijms22052535

PMCID:: PMC7961504

Abstract Article PDF–1.8M

Select item 79223795.

Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion

Yeon-Su Lee, Xiaoyong Bao, Hwi-Ho Lee, Jiyoung Joan Jang, Enkhjin Saruuldalai, Gaeul Park, Wonkyun Ronny Im, Jong-Lyul Park, Seon-Young Kim, Sooyong Shin, Sung Ho Jeon, Sangmin Kang, Hyun-Sung Lee, Ju-Seog Lee, Ke Zhang, Eun Jung Park, In-Hoo Kim, Yong Sun Lee

Int J Mol Sci. 2021 Feb; 22(4): 2003. Published online 2021 Feb 18. doi: 10.3390/ijms22042003

PMCID:: PMC7922379

Abstract Article PDF–1.7M

Select item 64867566.

Mechanism mediated by a noncoding RNA, nc886, in the cytotoxicity of a DNA-reactive compound

Nawapol Kunkeaw, Yeon-Su Lee, Wonkyun Ronny Im, Jiyoung Joan Jang, Min-Ji Song, Bobae Yang, Jong-Lyul Park, Seon-Young Kim, Yongsuk Ku, Yoosik Kim, Sangmin Kang, Hye-ram Jo, Jae-Hoon Jeong, Hyun-Sung Lee, Ju-Seog Lee, Hyoung-Pyo Kim, Betty H. Johnson, In-Hoo Kim, Yong Sun Lee

Proc Natl Acad Sci U S A. 2019 Apr 23; 116(17): 8289–8294. Published online 2019 Apr 4. doi: 10.1073/pnas.1814510116

PMCID:: PMC6486756

Abstract Article PDF–1.3M

Select item 63018087.

MicroRNA-886-3P functions as a tumor suppressor in small cell lung cancer

Jie Shen, Wei Zhou, Nan Bi, Yong-Mei Song, Fu-Quan Zhang, Qi-Min Zhan, Lv-Hua Wang

Cancer Biol Ther. 2018; 19(12): 1185–1192. Published online 2018 Sep 19. doi: 10.1080/15384047.2018.1491505

PMCID:: PMC6301808

Abstract Article PDF–1.5M

Select item 57973908.

Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth

Rafael Sebastián Fort, Cecilia Mathó, Murilo Vieira Geraldo, María Carolina Ottati, Alex Shimura Yamashita, Kelly Cristina Saito, Katia Ramos Moreira Leite, Manuel Méndez, Noemí Maedo, Laura Méndez, Beatriz Garat, Edna Teruko Kimura, José Roberto Sotelo-Silveira, María Ana Duhagon

BMC Cancer. 2018; 18: 127. Published online 2018 Feb 2. doi: 10.1186/s12885-018-4049-7

PMCID:: PMC5797390

Abstract Article PDF–1.4M

Select item 53650499.

Silencing nc886, a Non-Coding RNA, Induces Apoptosis of Human Endometrial Cancer Cells-1A In Vitro

Zhuoying Hu, Hongyu Zhang, Liangdan Tang, Meng Lou, Yanqing Geng

Med Sci Monit. 2017; 23: 1317–1324. Published online 2017 Mar 16. doi: 10.12659/MSM.900320

PMCID:: PMC5365049

Abstract Article PDF–1.7M

Select item 450079510.

A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression

Yong Sun Lee

Genomics Inform. 2015 Jun; 13(2): 26–30. Published online 2015 Jun 30. doi: 10.5808/GI.2015.13.2.26

PMCID:: PMC4500795

Abstract Article PDF–1.1M

Select item 446462911.

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

Matt J Silver, Noah J Kessler, Branwen J Hennig, Paula Dominguez-Salas, Eleonora Laritsky, Maria S Baker, Cristian Coarfa, Hector Hernandez-Vargas, Jovita M Castelino, Michael N Routledge, Yun Yun Gong, Zdenko Herceg, Yong Sun Lee, Kwanbok Lee, Sophie E Moore, Anthony J Fulford, Andrew M Prentice, Robert A Waterland

Genome Biol. 2015; 16(1): 118. Published online 2015 Jun 11. doi: 10.1186/s13059-015-0660-y

PMCID:: PMC4464629

Abstract Article PDF–2.8M

Select item 411653312.

nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer

Kwang-Soo Lee, Jong-Lyul Park, Kwanbok Lee, Lauren E. Richardson, Betty H. Johnson, Hyun-Sung Lee, Ju-Seog Lee, Sang-Bae Kim, Oh-Hyung Kwon, Kyu Sang Song, Yong Sung Kim, Hassan Ashktorab, Duane T. Smoot, Sung Ho Jeon, Seon-Young Kim, Yong Sun Lee

Oncotarget. 2014 Jun; 5(11): 3944–3955. Published online 2014 May 31. doi: 10.18632/oncotarget.2047

PMCID:: PMC4116533

Abstract Article PDF–1.5M

Select item 411649613.

Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis

Hyun-Sung Lee, Kwanbok Lee, Hee-Jin Jang, Geon Kook Lee, Jong-Lyul Park, Seon-Young Kim, Sang-Bae Kim, Betty H. Johnson, Jae Ill Zo, Ju-Seog Lee, Yong Sun Lee

Oncotarget. 2014 Jun; 5(11): 3472–3481. Published online 2014 Apr 27. doi: 10.18632/oncotarget.1927

PMCID:: PMC4116496

Abstract Article PDF–4.3M

Select item 406383714.

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer

Valeria Romanelli, Kazuhiko Nakabayashi, Miguel Vizoso, Sebastián Moran, Isabel Iglesias-Platas, Naoko Sugahara, Naoko Sugahara, Carlos Simón, Carlos Simón, Kenichiro Hata, Kenichiro Hata, Manel Esteller, Manel Esteller, Franck Court, Franck Court, David Monk, David Monk

Epigenetics. 2014 May 1; 9(5): 783–790. Published online 2014 Mar 3. doi: 10.4161/epi.28323

PMCID:: PMC4063837

Abstract Article PDF–3.8M

Select item 386979615.

Cell death/proliferation roles for nc886, a non-coding RNA, in the Protein Kinase R pathway in cholangiocarcinoma

Nawapol Kunkeaw, Sung Ho Jeon, Kwanbok Lee, Betty H. Johnson, Suebpong Tanasanvimon, Milind Javle, Chawalit Pairojkul, Yaovalux Chamgramol, Wipaporn Wongfieng, Bin Gong, Chanvit Leelayuwat, Yong Sun Lee

Oncogene. Author manuscript; available in PMC 2013 Dec 20.

Published in final edited form as: Oncogene. 2013 Aug 8; 32(32): 10.1038/onc.2012.382. Published online 2012 Aug 27. doi: 10.1038/onc.2012.382

PMCID:: PMC3869796

Abstract Article PDF–5.2M

Select item 384915716.

Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction

Elena Miñones-Moyano, Marc R. Friedländer, Joan Pallares, Birgit Kagerbauer, Sílvia Porta, Georgia Escaramís, Isidre Ferrer, Xavier Estivill, Eulàlia Martí

RNA Biol. 2013 Jul 1; 10(7): 1093–1106. Published online 2013 May 1. doi: 10.4161/rna.24813

PMCID:: PMC3849157

Abstract Article PDF–2.2M

Select item 375705017.

Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation

Anupam Paliwal, Alexis M. Temkin, Kristi Kerkel, Alexander Yale, Iveta Yotova, Natalia Drost, Simon Lax, Chia-Ling Nhan-Chang, Charles Powell, Alain Borczuk, Abraham Aviv, Ronald Wapner, Xiaowei Chen, Peter L. Nagy, Nicholas Schork, Catherine Do, Ali Torkamani, Benjamin Tycko

PLoS Genet. 2013 Aug; 9(8): e1003622. Published online 2013 Aug 29. doi: 10.1371/journal.pgen.1003622

PMCID:: PMC3757050

Abstract Article PDF–6.2M

Select item 349731618.

A Tumor Surveillance Model: A Non-Coding RNA Senses Neoplastic Cells and Its Protein Partner Signals Cell Death

Sung Ho Jeon, Betty H. Johnson, Yong Sun Lee

Int J Mol Sci. 2012; 13(10): 13134–13139. Published online 2012 Oct 12. doi: 10.3390/ijms131013134

PMCID:: PMC3497316

Abstract Article PDF–363K

Select item 325122919.

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

Marianne Bach Treppendahl, Xiangning Qiu, Alexandra Søgaard, Xiaojing Yang, Cecilie Nandrup-Bus, Christoffer Hother, Mette Klarskov Andersen, Lars Kjeldsen, Lars Möllgaard, Eva Hellström-Lindberg, Johan Jendholm, Bo T. Porse, Peter A. Jones, Gangning Liang, Kirsten Grønbæk

Blood. 2012 Jan 5; 119(1): 206–216. Prepublished online 2011 Nov 4. doi: 10.1182/blood-2011-06-362541