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Select item 109032441.

TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways

Tingting Ning, Mengran Zhao, Nan Zhang, Zhaoqing Wang, Shutian Zhang, Mo Liu, Shengtao Zhu

Exp Biol Med (Maywood) 2023 Dec; 248(23): 2210–2218. Published online 2023 Dec 6. doi: 10.1177/15353702231211970

PMCID:: PMC10903244

Abstract Article PDF–7.6M

Select item 108195762.

Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation

Keyera Randolph, Usman Hyder, Ashwini Challa, Erick Perez, Iván D’Orso

Viruses. 2024 Jan; 16(1): 116. Published online 2024 Jan 13. doi: 10.3390/v16010116

PMCID:: PMC10819576

Abstract Article PDF–4.4M

Select item 105899703.

E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells

Manman Liang, Zhengui Sun, Xingwu Chen, Lijing Wang, Hanli Wang, Lilong Qin, Wenying Zhao, Biao Geng

J Exp Clin Cancer Res. 2023; 42: 275. Published online 2023 Oct 21. doi: 10.1186/s13046-023-02862-3

PMCID:: PMC10589970

Abstract Article PDF–9.1M

Select item 102980874.

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells

Yao-Jen Chang, Steven Lin, Zhi-Fu Kang, Bin-Jon Shen, Wen-Hai Tsai, Wen-Ching Chen, Hsin-Pin Lu, Yu-Lun Su, Shu-Jen Chou, Shu-Yu Lin, Sheng-Wei Lin, Yin-Jung Huang, Hsin-Hui Wang, Ching-Jin Chang

Int J Mol Sci. 2023 Jun; 24(12): 9830. Published online 2023 Jun 6. doi: 10.3390/ijms24129830

PMCID:: PMC10298087

Abstract Article PDF–4.3M

Select item 102014375.

A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis

Qianhui Du, Emily C Stow, Dawn LaCoste, Benjamin Freeman, Melody Baddoo, Afzaal M Shareef, Kyle M Miller, Victoria P Belancio

Nucleic Acids Res. 2023 May 22; 51(9): 4429–4450. Published online 2023 Apr 18. doi: 10.1093/nar/gkad247

PMCID:: PMC10201437

Abstract Article PDF–6.4M

Select item 98275496.

The bromodomain protein TRIM28 controls the balance between growth and invasiveness in melanoma

William A Nyberg, Diego A Velasquez‐Pulgarin, Tianlin He, Maria Sjöstrand, Lucia Pellé, Ruxandra Covacu, Alexander Espinosa

EMBO Rep. 2023 Jan; 24(1): e54944. Published online 2022 Nov 7. doi: 10.15252/embr.202254944

PMCID:: PMC9827549

Abstract Article PDF–2.1M

Select item 95533397.

Integrated Bioinformatics and Experimental Analysis Identified TRIM28 a Potential Prognostic Biomarker and Correlated with Immune Infiltrates in Liver Hepatocellular Carcinoma

Jiyu Han, Yanhong Wang, Haichao Zhou, Songtao Ai, Daqian Wan

Comput Math Methods Med. 2022; 2022: 6267851. Published online 2022 Oct 4. doi: 10.1155/2022/6267851

PMCID:: PMC9553339

Abstract Article PDF–3.6M

Select item 86700368.

Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas

Peipei Yuan, Jun Yan, Shuang Wang, Yang Guo, Xueyan Xi, Song Han, Jun Yin, Biwen Peng, Xiaohua He, Jochen Bodem, Wanhong Liu

Retrovirology. 2021; 18: 38. Published online 2021 Dec 13. doi: 10.1186/s12977-021-00584-y

PMCID:: PMC8670036

Abstract Article PDF–3.5M

Select item 84342879.

TRIM28 Selective Nanobody Reduces Glioblastoma Stem Cell Invasion

Andrej Porčnik, Metka Novak, Barbara Breznik, Bernarda Majc, Barbara Hrastar, Neja Šamec, Alja Zottel, Ivana Jovčevska, Miloš Vittori, Ana Rotter, Radovan Komel, Tamara Lah Turnšek

Molecules. 2021 Sep; 26(17): 5141. Published online 2021 Aug 25. doi: 10.3390/molecules26175141

PMCID:: PMC8434287

Abstract Article PDF–1.5M

Select item 839452410.

Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs

Sylwia Mazurek, Urszula Oleksiewicz, Patrycja Czerwińska, Joanna Wróblewska, Marta Klimczak, Maciej Wiznerowicz

Cells. 2021 Aug; 10(8): 1933. Published online 2021 Jul 29. doi: 10.3390/cells10081933

PMCID:: PMC8394524

Abstract Article PDF–8.5M

Select item 825263011.

TRIM28 variants and Wilms' tumour predisposition

Janna A Hol, Illja J Diets, Ronald R de Krijger, Marry M van den Heuvel‐Eibrink, Marjolijn CJ Jongmans, Roland P Kuiper

J Pathol. 2021 Jul; 254(4): 494–504. Published online 2021 Mar 15. doi: 10.1002/path.5639

PMCID:: PMC8252630

Abstract Article PDF–14M

Select item 765520612.

TRIM28 is a distinct prognostic biomarker that worsens the tumor immune microenvironment in lung adenocarcinoma

Jie Liu, Xiao Han, Lijuan Chen, Dong Han, Xiaoqian Mu, Xiufeng Hu, Hongbo Wu, Huijuan Wu, Wenjing Liu, Yanqiu Zhao

Aging (Albany NY) 2020 Oct 31; 12(20): 20308–20331. Published online 2020 Oct 22. doi: 10.18632/aging.103804

PMCID:: PMC7655206

Abstract Article PDF–4.9M

Select item 706475413.

Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner

Svenja Siebels, Manja Czech-Sioli, Michael Spohn, Claudia Schmidt, Juliane Theiss, Daniela Indenbirken, Thomas Günther, Adam Grundhoff, Nicole Fischer

mBio. 2020 Mar-Apr; 11(2): e00142-20. Published online 2020 Mar 10. doi: 10.1128/mBio.00142-20

PMCID:: PMC7064754

Abstract Article PDF–6.7M

Select item 681528114.

Expression and Significance of TRIM 28 in Squamous Carcinoma of Esophagus

Bo Liu, Xiujuan Li, Fengxi Liu, Fengyu Li, Shuxia Wei, Junchao Liu, Yang Lv

Pathol Oncol Res. 2019; 25(4): 1645–1652. Published online 2018 Nov 27. doi: 10.1007/s12253-018-0558-6

PMCID:: PMC6815281

Abstract Article PDF–831K

Select item 629260515.

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children’s Oncology Group study

Amy E. Armstrong, Samantha Gadd, Vicki Huff, Daniela S. Gerhard, Jeffrey S. Dome, Elizabeth J. Perlman

PLoS One. 2018; 13(12): e0208936. Published online 2018 Dec 13. doi: 10.1371/journal.pone.0208936

PMCID:: PMC6292605

Abstract Article PDF–909K

Select item 617230316.

Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells

Tim Krischuns, Franziska Günl, Lea Henschel, Marco Binder, Joschka Willemsen, Sebastian Schloer, Ursula Rescher, Vanessa Gerlt, Gert Zimmer, Carolin Nordhoff, Stephan Ludwig, Linda Brunotte

Front Immunol. 2018; 9: 2229. Published online 2018 Sep 28. doi: 10.3389/fimmu.2018.02229

PMCID:: PMC6172303

Abstract Article PDF–6.9M

Select item 600545917.

Germline mutations and somatic inactivation of TRIM28 in Wilms tumour

Benjamin J. Halliday, Ryuji Fukuzawa, David M. Markie, Richard G. Grundy, Jackie L. Ludgate, Michael A. Black, Jane E. Skeen, Robert J. Weeks, Daniel R. Catchpoole, Aedan G. K. Roberts, Anthony E. Reeve, Ian M. Morison

PLoS Genet. 2018 Jun; 14(6): e1007399. Published online 2018 Jun 18. doi: 10.1371/journal.pgen.1007399

PMCID:: PMC6005459

Abstract Article PDF–4.9M

Select item 589188618.

Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment

Seán Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O’Grady, Robert Cummins, Richard O’Kennedy, Elaine W. Kay, Gregor S. Kijanka

J Transl Med. 2018; 16: 89. Published online 2018 Apr 10. doi: 10.1186/s12967-018-1465-z

PMCID:: PMC5891886

Abstract Article PDF–1.6M

Select item 578575819.

TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes

Urszula Oleksiewicz, Marta Gładych, Ayush T. Raman, Holger Heyn, Elisabetta Mereu, Paula Chlebanowska, Anastazja Andrzejewska, Barbara Sozańska, Neha Samant, Katarzyna Fąk, Paulina Auguścik, Marcin Kosiński, Joanna P. Wróblewska, Katarzyna Tomczak, Katarzyna Kulcenty, Rafał Płoski, Przemysław Biecek, Manel Esteller, Parantu K. Shah, Kunal Rai, Maciej Wiznerowicz

Stem Cell Reports. 2017 Dec 12; 9(6): 2065–2080. Published online 2017 Nov 30. doi: 10.1016/j.stemcr.2017.10.031

PMCID:: PMC5785758

Abstract Article PDF–4.8M

Select item 576898720.

TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency

Yu Tao, Ming-Ren Yen, Tsotne Chitiashvili, Haruko Nakano, Rachel Kim, Linzi Hosohama, Yao Chang Tan, Atsushi Nakano, Pao-Yang Chen, Amander T. Clark

Stem Cell Reports. 2018 Jan 9; 10(1): 243–256. Published online 2017 Dec 28. doi: 10.1016/j.stemcr.2017.11.020

PMCID:: PMC5768987

Abstract Article PDF–3.6M

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