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Items: 1 to 20 of 68

1.
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein–enhanced Expression of Endothelial PAI-1
Mingming Han, Deepesh Pandey
Am J Respir Cell Mol Biol. 2021 Sep; 65(3): 300–308. Published online 2021 Mar 30. doi: 10.1165/rcmb.2020-0544OC
PMCID:
PMC8485999
AbstractArticlePDF–993K
2.
ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA
Moritz Messner, Santhosh Kumar Ghadge, Thomas Maurer, Michael Graber, Simon Staggl, Sarah Christine Maier, Gerhard Pölzl, Marc-Michael Zaruba
Cells. 2020 Sep; 9(9): 1981. Published online 2020 Aug 28. doi: 10.3390/cells9091981
PMCID:
PMC7563344
AbstractArticlePDF–1.6M
3.
Ste24: An Integral Membrane Protein Zinc Metalloprotease with Provocative Structure and Emergent Biology
Brandon R. Goblirsch, Michael C. Wiener
J Mol Biol. 2020 Aug 21; 432(18): 5079–5090. Published online 2020 Mar 19. doi: 10.1016/j.jmb.2020.03.016
PMCID:
PMC7172729
AbstractArticlePDF–1.8M
4.
Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors
Kathleen M. Clark, Jermaine L. Jenkins, Nadia Fedoriw, Mark E. Dumont
Protein Sci. 2017 Feb; 26(2): 242–257. Published online 2016 Nov 11. doi: 10.1002/pro.3074
PMCID:
PMC5275749
AbstractArticlePDF–3.2M
5.
New ZMPSTE24 (FACE1) mutations in patients affected with restrictive dermopathy or related progeroid syndromes and mutation update
Claire Laure Navarro, Vera Esteves-Vieira, Sébastien Courrier, Amandine Boyer, Thuy Duong Nguyen, Le Thi Thanh Huong, Peter Meinke, Winnie Schröder, Valérie Cormier-Daire, Yves Sznajer, David J Amor, Kristina Lagerstedt, Martine Biervliet, Peter C van den Akker, Pierre Cau, Patrice Roll, Nicolas Lévy, Catherine Badens, Manfred Wehnert, Annachiara De Sandre-Giovannoli
Eur J Hum Genet. 2014 Aug; 22(8): 1002–1011. Published online 2013 Oct 30. doi: 10.1038/ejhg.2013.258
PMCID:
PMC4350588
AbstractArticlePDF–1.8M
6.
Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity
Jemima Barrowman, Patricia A. Wiley, Sarah E. Hudon-Miller, Christine A. Hrycyna, Susan Michaelis
Hum Mol Genet. 2012 Sep 15; 21(18): 4084–4093. Published online 2012 Jun 19. doi: 10.1093/hmg/dds233
PMCID:
PMC3428156
AbstractArticlePDF–368K
7.
Homozygous null mutations in ZMPSTE24 in restrictive dermopathy: evidence of genetic heterogeneity
Zahid Ahmad, Shubha R Phadke, Ellen Arch, Jonathan Glass, Anil K. Agarwal, Abhimanyu Garg
Clin Genet. Author manuscript; available in PMC 2013 Feb 1.
Published in final edited form as: Clin Genet. 2012 Feb; 81(2): 158–164. Published online 2010 Nov 25. doi: 10.1111/j.1399-0004.2010.01580.x
PMCID:
PMC3117019
AbstractArticlePDF–403K
8.
Early Onset Mandibuloacral Dysplasia due to Compound Heterozygous Mutations in ZMPSTE24
Zahid Ahmad, Elaine Zackai, Livija Medne, Abhimanyu Garg
Am J Med Genet A. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Am J Med Genet A. 2010 Nov; 152A(11): 2703–2710. doi: 10.1002/ajmg.a.33664
PMCID:
PMC2965306
AbstractArticlePDF–906K
9.
Severe mandibuloacral dysplasia caused by novel compound heterozygous ZMPSTE24 mutations in two Japanese siblings
Y Miyoshi, M Akagi, AK Agarwal, N Namba, K Kato-Nishimura, I Mohri, M Yamagata, S Nakajima, S Mushiake, M Shima, RJ Auchus, M Taniike, A Garg, K Ozono
Clin Genet. Author manuscript; available in PMC 2009 Aug 26.
Published in final edited form as: Clin Genet. 2008 Jun; 73(6): 535–544. Published online 2008 Apr 22. doi: 10.1111/j.1399-0004.2008.00992.x
PMCID:
PMC2732118
AbstractArticlePDF–2.3M
10.
Prelamin A and ZMPSTE24 in premature and physiological aging
Howard J. Worman, Susan Michaelis
Nucleus. 2023; 14(1): 2270345. Published online 2023 Oct 26. doi: 10.1080/19491034.2023.2270345
PMCID:
PMC10730219
AbstractArticlePDF–2.3M
11.
Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24
Timothy D. Babatz, Eric D. Spear, Wenxin Xu, Olivia L. Sun, Laiyin Nie, Elisabeth P. Carpenter, Susan Michaelis
J Biol Chem. 2021 Jan-Jun; 296: 100165. Published online 2020 Dec 11. doi: 10.1074/jbc.RA120.015792
PMCID:
PMC7948416
AbstractArticlePDF–1.6M
12.
OMA1—an integral membrane protease?
Marcel V. Alavi
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2021 Feb; 1869(2): 140558. Published online 2020 Oct 29. doi: 10.1016/j.bbapap.2020.140558
PMCID:
PMC7770061
AbstractArticlePDF–1.1M
13.
The tripartite architecture of the eukaryotic integral membrane protein zinc metalloprotease Ste24
Brandon R. Goblirsch, Edward E. Pryor, Jr, Michael C. Wiener
Proteins. 2020 Apr; 88(4): 604–615. Published online 2019 Nov 5. doi: 10.1002/prot.25841
PMCID:
PMC7168092
AbstractArticlePDF–3.3M
14.
A Humanized Yeast System to Analyze Cleavage of Prelamin A by ZMPSTE24
Eric D. Spear, Rebecca F. Alford, Tim D. Babatz, Kaitlin M. Wood, Otto W. Mossberg, Kamsi Odinammadu, Khurts Shilagardi, Jeffrey J. Gray, Susan Michaelis
Methods. Author manuscript; available in PMC 2020 Mar 15.
Published in final edited form as: Methods. 2019 Mar 15; 157: 47–55. Published online 2019 Jan 6. doi: 10.1016/j.ymeth.2019.01.001
PMCID:
PMC6401292
AbstractArticlePDF–1.5M
15.
ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability
Eric D. Spear, Erh-Ting Hsu, Laiyin Nie, Elisabeth P. Carpenter, Christine A. Hrycyna, Susan Michaelis
Dis Model Mech. 2018 Jul 1; 11(7): dmm033670. Published online 2018 Jul 13. doi: 10.1242/dmm.033670
PMCID:
PMC6078402
AbstractArticle
16.
A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder
Yuexia Wang, Uta Lichter-Konecki, Kwame Anyane-Yeboa, Jessica E. Shaw, Jonathan T. Lu, Cecilia Östlund, Ji-Yeon Shin, Lorraine N. Clark, Gregg G. Gundersen, Peter L. Nagy, Howard J. Worman
J Cell Sci. 2016 May 15; 129(10): 1975–1980. doi: 10.1242/jcs.187302
PMCID:
PMC4878994
AbstractArticle
17.
A Potent HIV Protease Inhibitor, Darunavir, Does Not Inhibit ZMPSTE24 or Lead to an Accumulation of Farnesyl-prelamin A in Cells
Catherine Coffinier, Sarah E. Hudon, Roger Lee, Emily A. Farber, Chika Nobumori, Jeffrey H. Miner, Douglas A. Andres, H. Peter Spielmann, Christine A. Hrycyna, Loren G. Fong, Stephen G. Young
J Biol Chem. 2008 Apr 11; 283(15): 9797–9804. doi: 10.1074/jbc.M709629200
PMCID:
PMC2442292
AbstractArticlePDF–483K
18.
Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy
Casey L. Moulson, Gloriosa Go, Allard C. van der Wal, J. Henk Sillevis Smitt, Johanna M. van Hagen, Jeffrey H. Miner
J Invest Dermatol. Author manuscript; available in PMC 2006 May 1.
Published in final edited form as: J Invest Dermatol. 2005 Nov; 125(5): 913–919. doi: 10.1111/j.0022-202X.2005.23846.x
PMCID:
PMC1360172
AbstractArticlePDF–508K
19.
The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation
Khurts Shilagardi, Eric D. Spear, Rachy Abraham, Diane E. Griffin, Susan Michaelis
mBio. 2022 Sep-Oct; 13(5): e02543-22. Published online 2022 Oct 5. doi: 10.1128/mbio.02543-22
PMCID:
PMC9601121
AbstractArticlePDF–1.4M
20.
Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides
Emily R. Hildebrandt, Buenafe T. Arachea, Michael C. Wiener, Walter K. Schmidt
J Biol Chem. 2016 Jul 1; 291(27): 14185–14198. Published online 2016 Apr 29. doi: 10.1074/jbc.M116.718197
PMCID:
PMC4933176
AbstractArticlePDF–2.6M

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