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Select item 86714981.

The distinct effects of P18 overexpression on different stages of hematopoiesis involve TGF-β and NF-κB signaling

Danying Yi, Lijiao Zhu, Yuanling Liu, Jiahui Zeng, Jing Chang, Wencui Sun, Jiawen Teng, Yonggang Zhang, Yong Dong, Xu Pan, Yijin Chen, Ya Zhou, Mowen Lai, Qiongxiu Zhou, Jiaxin Liu, Bo Chen, Feng Ma

Sci Rep. 2021; 11: 24014. Published online 2021 Dec 14. doi: 10.1038/s41598-021-03263-2

PMCID:: PMC8671498

Abstract Article PDF–1.8M

Select item 72642732.

A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor

Carla Eller, Laura Heydmann, Che C. Colpitts, Houssein El Saghire, Federica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S. Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E. Root, Eloi R. Verrier, Thomas F. Baumert

Nat Commun. 2020; 11: 2707. Published online 2020 Jun 1. doi: 10.1038/s41467-020-16517-w

PMCID:: PMC7264273

Abstract Article PDF–3.0M

Select item 64534973.

Role of CDKN2C Copy Number in Sporadic Medullary Thyroid Carcinoma

Elizabeth G. Grubbs, Michelle D. Williams, Paul Scheet, Selina Vattathil, Nancy D. Perrier, Jeffrey E. Lee, Robert F. Gagel, Tao Hai, Lei Feng, Maria E. Cabanillas, Gilbert J. Cote

Thyroid. 2016 Nov 1; 26(11): 1553–1562. Published online 2016 Nov 1. doi: 10.1089/thy.2016.0224

PMCID:: PMC6453497

Abstract Article PDF–308K

Select item 25817924.

Deletions of CDKN2C in Multiple Myeloma: Biological and Clinical Implications

Paola E. Leone, Brian A. Walker, Matthew W. Jenner, Laura Chiecchio, GianPaolo Dagrada, Rebecca K.M. Protheroe, David C. Johnson, Nicholas J. Dickens, Jose Luis Brito, Monica Else, David Gonzalez, Fiona M. Ross, Selina Chen-Kiang, Faith E. Davies, Gareth J. Morgan

Clin Cancer Res. Author manuscript; available in PMC 2009 Apr 1.

Published in final edited form as: Clin Cancer Res. 2008 Oct 1; 14(19): 6033–6041. doi: 10.1158/1078-0432.CCR-08-0347

PMCID:: PMC2581792

Abstract Article PDF–839K

Select item 100237685.

Novel germline variants of CDKN1B and CDKN2C identified during screening for familial primary hyperparathyroidism

I. Mazarico-Altisent, I. Capel, N. Baena, M. R. Bella-Cueto, S. Barcons, X. Guirao, L. Albert, A. Cano, R. Pareja, A. Caixàs, M. Rigla

J Endocrinol Invest. 2023; 46(4): 829–840. Published online 2022 Nov 5. doi: 10.1007/s40618-022-01948-7

PMCID:: PMC10023768

Abstract Article PDF–1.0M

Select item 74535116.

PRMT6 serves an oncogenic role in lung adenocarcinoma via regulating p18

Jie Tang, Qinge Meng, Ruirui Shi, Youqi Xu

Mol Med Rep. 2020 Oct; 22(4): 3161–3172. Published online 2020 Aug 3. doi: 10.3892/mmr.2020.11402

PMCID:: PMC7453511

Abstract Article PDF–1.8M

Select item 71931687.

miR‐21‐5p promotes cell proliferation and G1/S transition in melanoma by targeting CDKN2C

Zhaohui Yang, Bo Liao, Xiaoyan Xiang, Sha Ke

FEBS Open Bio. 2020 May; 10(5): 752–760. Published online 2020 Mar 24. doi: 10.1002/2211-5463.12819

PMCID:: PMC7193168

Abstract Article PDF–2.2M

Select item 70487878.

MCL1 binding to the reverse BH3 motif of P18INK4C couples cell survival to cell proliferation

Robert H. Whitaker, William J. Placzek

Cell Death Dis. 2020 Feb; 11(2): 156. Published online 2020 Feb 28. doi: 10.1038/s41419-020-2351-1

PMCID:: PMC7048787

Abstract Article PDF–1.4M

Select item 57518839.

Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being Genes in Regions Associated with Adverse Survival

Kevin D. Boyd, Fiona M. Ross, Brian A. Walker, Christopher P. Wardell, William J. Tapper, Laura Chiecchio, GianPaolo Dagrada, Zoe J Konn, Walter M. Gregory, Graham H Jackson, J Anthony Child, Faith E. Davies, Gareth J. Morgan

Clin Cancer Res. Author manuscript; available in PMC 2018 Jan 3.

Published in final edited form as: Clin Cancer Res. 2011 Dec 15; 17(24): 7776–7784. Published online 2011 Oct 12. doi: 10.1158/1078-0432.CCR-11-1791

PMCID:: PMC5751883

Abstract Article PDF–1.5M

Select item 488930910.

CDKIs p18^INK4c and p57^Kip2 are involved in quiescence of CML leukemic stem cells after treatment with TKI

Dafne Moreno-Lorenzana, Sócrates Avilés-Vazquez, Miguel Angel Sandoval Esquivel, Antonio Alvarado-Moreno, Vianney Ortiz-Navarrete, Héctor Torres-Martínez, Manuel Ayala-Sánchez, Héctor Mayani, Antonieta Chavez-Gonzalez

Cell Cycle. 2016; 15(9): 1276–1287. Published online 2016 Mar 17. doi: 10.1080/15384101.2016.1160976

PMCID:: PMC4889309

Abstract Article PDF–1.1M

Select item 481348511.

High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation

Karine Robitaille, Jillian L. Rourke, Joanne E. McBane, Accalia Fu, Stephen Baird, Qiujiang Du, Tatsuya Kin, A. M. James Shapiro, Robert A. Screaton

J Biol Chem. 2016 Feb 26; 291(9): 4614–4625. Published online 2016 Jan 6. doi: 10.1074/jbc.M115.683912

PMCID:: PMC4813485

Abstract Article PDF–2.9M

Select item 456336912.

DNA methyltransferase 3A promotes cell proliferation by silencing CDK inhibitor p18^INK4C in gastric carcinogenesis

He Cui, Chengcheng Zhao, Pihai Gong, Ling Wang, Huazhang Wu, Kun Zhang, Rongping Zhou, Li Wang, Ting Zhang, Sheng Zhong, Hong Fan

Sci Rep. 2015; 5: 13781. Published online 2015 Sep 9. doi: 10.1038/srep13781

PMCID:: PMC4563369

Abstract Article PDF–1.6M

Select item 424823113.

Contrasting behavior of the p18^INK4c and p16^INK4a tumor suppressors in both replicative and oncogene-induced senescence

Sladjana Gagrica, Sharon Brookes, Emma Anderton, Janice Rowe, Gordon Peters

Cancer Res. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Cancer Res. 2012 Jan 1; 72(1): 165–175. Published online 2011 Nov 11. doi: 10.1158/0008-5472.CAN-11-2552

PMCID:: PMC4248231

Abstract Article PDF–1.5M

Select item 340671414.

Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18

Yumei Du, Guangyao Kong, Xiaona You, Shuai Zhang, Tao Zhang, Yuen Gao, Lihong Ye, Xiaodong Zhang

J Biol Chem. 2012 Jul 27; 287(31): 26302–26311. Published online 2012 Jun 8. doi: 10.1074/jbc.M112.342113

PMCID:: PMC3406714

Abstract Article PDF–3.0M

Select item 193992715.

Mutational Analysis of p27 (CDKN1B) and p18 (CDKN2C) in Sporadic Pancreatic Endocrine Tumors Argues against Tumor-Suppressor Function

Daniel Lindberg, Göran Åkerström, Gunnar Westin

Neoplasia. 2007 Jul; 9(7): 533–535. doi: 10.1593/neo.07328

PMCID:: PMC1939927

Abstract Article PDF–51K

Select item 31714416.

Structural basis of inhibition of CDK–cyclin complexes by INK4 inhibitors

Philip D. Jeffrey, Lily Tong, Nikola P. Pavletich

Genes Dev. 2000 Dec 15; 14(24): 3115–3125. doi: 10.1101/gad.851100

PMCID:: PMC317144

Abstract Article PDF–8.4M

Select item 792567917.

Stabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replication

Yueshuo Li, Feng Shi, Jianmin Hu, Longlong Xie, Lin Zhao, Min Tang, Xiangjian Luo, Mao Ye, Hui Zheng, Min Zhou, Na Liu, Ann M. Bode, Jia Fan, Jian Zhou, Qiang Gao, Shuangjian Qiu, Weizhong Wu, Xin Zhang, Weihua Liao, Ya Cao

NPJ Precis Oncol. 2021; 5: 14. Published online 2021 Mar 2. doi: 10.1038/s41698-021-00153-8