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Select item 74842381.

TRAF3IP2 mediates obesity-associated vascular insulin resistance and dysfunction in male mice

Zachary I. Grunewald, Francisco I. Ramirez-Perez, Makenzie L. Woodford, Mariana Morales-Quinones, Salvador Mejia, Camila Manrique-Acevedo, Ulrich Siebenlist, Luis A. Martinez-Lemus, Bysani Chandrasekar, Jaume Padilla

Hypertension. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Hypertension. 2020 Oct; 76(4): 1319–1329. Published online 2020 Aug 24. doi: 10.1161/HYPERTENSIONAHA.120.15262

PMCID:: PMC7484238

Abstract Article PDF–2.0M

Select item 53131052.

Targeting TRAF3IP2 by Genetic and Interventional Approaches Inhibits Ischemia/Reperfusion-induced Myocardial Injury and Adverse Remodeling

John M. Erikson, Anthony J. Valente, Srinivas Mummidi, Hemanth Kumar Kandikattu, Vincent G. DeMarco, Shawn B. Bender, William P. Fay, Ulrich Siebenlist, Bysani Chandrasekar

J Biol Chem. 2017 Feb 10; 292(6): 2345–2358. Published online 2017 Jan 4. doi: 10.1074/jbc.M116.764522

PMCID:: PMC5313105

Abstract Article PDF–2.8M

Select item 50355783.

TRAF3IP2 mediates atherosclerotic plaque development and vulnerability in ApoE⁻^/⁻ mice

Sakamuri Siva Sankara Vara Prasad, Yusuke Higashi, Sergiy Sukhanov, Jalahalli M Siddesha, Patrice Delafontaine, Ulrich Siebenlist, Bysani Chandrasekar

Atherosclerosis. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Atherosclerosis. 2016 Sep; 252: 153–160. Published online 2016 May 19. doi: 10.1016/j.atherosclerosis.2016.05.029

PMCID:: PMC5035578

Abstract Article PDF–863K

Select item 50166814.

Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction

Manjunath Yariswamy, Tadashi Yoshida, Anthony J. Valente, Hemanth Kumar Kandikattu, Siva S. V. P. Sakamuri, Jalahalli M. Siddesha, Sergiy Sukhanov, Zubaida Saifudeen, Lixin Ma, Ulrich Siebenlist, Jason D. Gardner, Bysani Chandrasekar

J Biol Chem. 2016 Sep 9; 291(37): 19425–19436. Published online 2016 Jul 27. doi: 10.1074/jbc.M116.724138

PMCID:: PMC5016681

Abstract Article PDF–2.3M

Select item 48616975.

TRAF3IP2 Mediates Aldosterone/Salt-Induced Cardiac Hypertrophy and Fibrosis

Siva S.V.P Sakamuri, Anthony J. Valente, Jalahalli M. Siddesha, Patrice Delafontaine, Ulrich Siebenlist, Jason D. Gardner, Bysani Chandrasekar

Mol Cell Endocrinol. Author manuscript; available in PMC 2017 Jul 5.

Published in final edited form as: Mol Cell Endocrinol. 2016 Jul 5; 429: 84–92. Published online 2016 Apr 1. doi: 10.1016/j.mce.2016.03.038

PMCID:: PMC4861697

Abstract Article PDF–4.2M

Select item 38939336.

Spontaneous loss of tolerance of autoreative B cell in Act1-deficient AM14 Tg rheumatoid factor (RF) mice

Natalia V. Giltiay, Yi Lu, Jaime L. Cullen, Trine N. Jørgensen, Mark J. Shlomchik, Xiaoxia Li

J Immunol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Immunol. 2013 Sep 1; 191(5): 2155–2163. Published online 2013 Jul 31. doi: 10.4049/jimmunol.1300152

PMCID:: PMC3893933

Abstract Article PDF–2.0M

Select item 37932477.

TRAF3IP2 mediates interleukin-18-induced cardiac fibroblast migration and differentiation

Anthony J. Valente, Siva S.V.P. Sakamuri, Jalahalli M. Siddesha, Tadashi Yoshida, Jason D. Gardner, Ramesh Prabhu, Ulrich Siebenlist, Bysani Chandrasekar

Cell Signal. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Cell Signal. 2013 Nov; 25(11): 2176–2184. Published online 2013 Jul 18. doi: 10.1016/j.cellsig.2013.07.013

PMCID:: PMC3793247

Abstract Article PDF–3.5M

Select item 36403048.

IL-17 Mediates Estrogen-deficient Osteoporosis in an Act1-dependent Manner

Carl J. DeSelm, Yoshifumi Takahata, Julia Warren, Jean C. Chappel, Taimur Khan, Xiaoxia Li, Caini Liu, Yongwon Choi, Youngmi Faith Kim, Wei Zou, Steven L. Teitelbaum

J Cell Biochem. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: J Cell Biochem. 2012 Sep; 113(9): 2895–2902. doi: 10.1002/jcb.24165

PMCID:: PMC3640304

Abstract Article PDF–1.7M

Select item 36068099.

CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction

Balachandar Venkatesan, Anthony J. Valente, Nitin A. Das, Andrea J. Carpenter, Tadashi Yoshida, Jean-Luc Delafontaine, Ulrich Siebenlist, Bysani Chandrasekar

Cell Signal. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Cell Signal. 2013 Jan; 25(1): 359–371. Published online 2012 Oct 17. doi: 10.1016/j.cellsig.2012.10.009

PMCID:: PMC3606809

Abstract Article PDF–5.3M

Select item 307563510.

IL-17-induced NF-κB Activation via CIKS/Act1: PHYSIOLOGIC SIGNIFICANCE AND SIGNALING MECHANISMS

Søren Ulrik Sønder, Sun Saret, Wanhu Tang, Dan E. Sturdevant, Stephen F. Porcella, Ulrich Siebenlist

J Biol Chem. 2011 Apr 15; 286(15): 12881–12890. Published online 2011 Feb 18. doi: 10.1074/jbc.M110.199547

PMCID:: PMC3075635

Abstract Article PDF–1.5M

Select item 840428111.

The m⁶A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis

Rami Bechara, Nilesh Amatya, Rachel D. Bailey, Yang Li, Felix EY Aggor, De-Dong Li, Chetan V. Jawale, Bianca M. Coleman, Ning Dai, Nandan S. Gokhale, Tiffany C. Taylor, Stacy M. Horner, Amanda C. Poholek, Anita Bansal, Partha S. Biswas, Sarah L. Gaffen

Sci Immunol. Author manuscript; available in PMC 2022 Jan 2.

Published in final edited form as: Sci Immunol. 2021 Jul 2; 6(61): eabd1287. doi: 10.1126/sciimmunol.abd1287

PMCID:: PMC8404281

Abstract Article PDF–2.5M

Select item 784014912.

IL-10 Dampens an IL-17–Mediated Periodontitis-Associated Inflammatory Network

Lu Sun, Mustafa Girnary, Lufei Wang, Yizu Jiao, Erliang Zeng, Kyle Mercer, Jinmei Zhang, Julie T. Marchesan, Ning Yu, Kevin Moss, Yu L. Lei, Steven Offenbacher, Shaoping Zhang

J Immunol. Author manuscript; available in PMC 2021 Apr 15.

Published in final edited form as: J Immunol. 2020 Apr 15; 204(8): 2177–2191. Published online 2020 Mar 13. doi: 10.4049/jimmunol.1900532

PMCID:: PMC7840149

Abstract Article PDF–1.3M

Select item 637980913.

IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility

Katarzyna Bulek, Xing Chen, Vandy Parron, Aparna Sundaram, Tomasz Herjan, Suidong Ouyang, Caini Liu, Alana Majors, Jarod Zepp, Ji Gao, Ashok Dongre, Malgorzata Bodaszewska-Lubas, Arnaud Echard, Mark Aronica, Julie Carman, Stavros Garantziotis, Dean Sheppard, Xiaoxia Li

J Immunol. 2019 Mar 1; 202(5): 1540–1548. Published online 2019 Jan 25. doi: 10.4049/jimmunol.1801025

PMCID:: PMC6379809

Abstract Article PDF–2.0M

Select item 542010214.

Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice

Annayya R. Aroor, Javad Habibi, Hemanth Kumar Kandikattu, Mona Garro-Kacher, Brady Barron, Dongqing Chen, Melvin R. Hayden, Adam Whaley-Connell, Shawn B. Bender, Thomas Klein, Jaume Padilla, James R. Sowers, Bysani Chandrasekar, Vincent G. DeMarco

Cardiovasc Diabetol. 2017; 16: 61. Published online 2017 May 5. doi: 10.1186/s12933-017-0544-4

PMCID:: PMC5420102

Abstract Article PDF–4.2M

Select item 414300715.

IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms

Hye-Lin Ha, Hongshan Wang, Prapaporn Pisitkun, Jin-Chul Kim, Ilaria Tassi, Wanhu Tang, Maria I. Morasso, Mark C. Udey, Ulrich Siebenlist

Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33): E3422–E3431. Published online 2014 Aug 4. doi: 10.1073/pnas.1400513111

PMCID:: PMC4143007

Abstract Article PDF–2.2M

Select item 366617516.

T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation

Shadi Swaidani, Katarzyna Bulek, Zizhen Kang, Muhammet Fatih Gulen, Caini Liu, Weiguo Yin, Amina Abbadi, Mark Aronica, Xiaoxia Li

J Immunol. Author manuscript; available in PMC 2013 May 29.

Published in final edited form as: J Immunol. 2011 Sep 15; 187(6): 3155–3164. Published online 2011 Aug 19. doi: 10.4049/jimmunol.1002790

PMCID:: PMC3666175

Abstract Article PDF–3.3M

Select item 328258517.

A CC′ Loop Decoy Peptide Blocks the Interaction Between Act1 and IL-17RA to Attenuate IL-17- and IL-25-Induced Inflammation

Caini Liu, Shadi Swaidani, Wen Qian, Zizhen Kang, Paige Sun, Yue Han, Chenhui Wang, Muhammet Fatih Gulen, Weiguo Yin, Chunjiang Zhang, Paul L Fox, Mark Aronica, Thomas A Hamilton, Saurav Misra, Junpeng Deng, Xiaoxia Li

Sci Signal. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Sci Signal. 2011 Nov 1; 4(197): ra72. Published online 2011 Nov 1. doi: 10.1126/scisignal.2001843

PMCID:: PMC3282585

Abstract Article PDF–4.2M

Select item 322525518.

The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation

Natalia V. Giltiay, Yi Lu, David Allman, Trine N. Jørgensen, Xiaoxia Li

J Immunol. Author manuscript; available in PMC 2011 Nov 28.

Published in final edited form as: J Immunol. 2010 Jul 1; 185(1): 99–109. Published online 2010 Jun 11. doi: 10.4049/jimmunol.0903312

PMCID:: PMC3225255

Abstract Article PDF–2.9M

Select item 307361819.

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

Zizhen Kang, Cengiz Zubeyir Altuntas, Muhammet Fatih Gulen, Caini Liu, Natalia Giltiay, Hongwei Qin, Liping Liu, Wen Qian, Richard M. Ransohoff, Cornelia Bergmann, Stephen Stohlman, Vincent K Tuohy, Xiaoxia Li

Immunity. Author manuscript; available in PMC 2011 Apr 11.

Published in final edited form as: Immunity. 2010 Mar 26; 32(3): 414–425. Published online 2010 Mar 18. doi: 10.1016/j.immuni.2010.03.004