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Select item 106672391.

ACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype

Michelle Shen, Shiqin Liu, Angus Toland, En-Chi Hsu, Alifiani B. Hartono, Busola R. Alabi, Merve Aslan, Holly M. Nguyen, Conner J. Sessions, Rosalie Nolley, Chanjuan Shi, Jiaoti Huang, James D. Brooks, Eva Corey, Tanya Stoyanova

Br J Cancer. 2023 Nov 23; 129(11): 1818–1828. Published online 2023 Oct 5. doi: 10.1038/s41416-023-02448-y

PMCID:: PMC10667239

Abstract Article PDF–5.3M

Select item 105204782.

Negative correlation between acetyl-CoA acyltransferase 2 and cetuximab resistance in colorectal cancer: Correlation between ACAA2 and cetuximab resistance in CRC

Yitao Yuan, Xun Sun, Mengling Liu, Suyao Li, Yu Dong, Keshu Hu, Jiayu Zhang, Bei Xu, Sining Ma, Hesheng Jiang, Pengcong Hou, Yufu Lin, Lu Gan, Tianshu Liu

Acta Biochim Biophys Sin (Shanghai) 2023 Sep 25; 55(9): 1467–1478. Published online 2023 Jun 13. doi: 10.3724/abbs.2023111

PMCID:: PMC10520478

Abstract Article PDF–3.1M

Select item 95117113.

LncRNA RPL34-AS1 suppresses the proliferation, migration and invasion of esophageal squamous cell carcinoma via targeting miR-575/ACAA2 axis

Hu Zhang, Enchun Pan, Ying Zhang, Chao Zhao, Qiwei Liu, Yuepu Pu, Lihong Yin

BMC Cancer. 2022; 22: 1017. Published online 2022 Sep 26. doi: 10.1186/s12885-022-10104-6

PMCID:: PMC9511711

Abstract Article PDF–7.9M

Select item 37534224.

HIV-1 Vpr Enhances PPARβ/δ-Mediated Transcription, Increases PDK4 Expression, and Reduces PDC Activity

Shashi Shrivastav, Liyan Zhang, Koji Okamoto, Hewang Lee, Claudia Lagranha, Yoshifusa Abe, Ashok Balasubramanyam, Gary D. Lopaschuk, Tomoshige Kino, Jeffrey B. Kopp

Mol Endocrinol. 2013 Sep; 27(9): 1564–1576. Published online 2013 Jul 10. doi: 10.1210/me.2012-1370

PMCID:: PMC3753422

Abstract Article

Select item 98036785.

DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release

Ye Hyung Lee, Bo Kyoung Suh, Unghwi Lee, Seung Hyun Ryu, Sung Ryong Shin, Sunghoe Chang, Sang Ki Park, Kwang Chul Chung

Cell Death Discov. 2022; 8: 503. Published online 2022 Dec 30. doi: 10.1038/s41420-022-01290-0

PMCID:: PMC9803678

Abstract Article PDF–3.4M

Select item 36694156.

Inhibition of UBE2D3 Expression Attenuates Radiosensitivity of MCF-7 Human Breast Cancer Cells by Increasing hTERT Expression and Activity

Wenbo Wang, Lei Yang, Liu Hu, Fen Li, Li Ren, Haijun Yu, Yu Liu, Ling Xia, Han Lei, Zhengkai Liao, Fuxiang Zhou, Conghua Xie, Yunfeng Zhou

PLoS One. 2013; 8(5): e64660. Published online 2013 May 31. doi: 10.1371/journal.pone.0064660

PMCID:: PMC3669415

Abstract Article PDF–353K

Select item 11340647.

Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes

Nabila Aboulaich, Julia P. Vainonen, Peter Strålfors, Alexander V. Vener

Biochem J. 2004 Oct 15; 383(Pt 2): 237–248. Prepublished online 2004 Jul 9. Published online 2004 Oct 8. doi: 10.1042/BJ20040647

PMCID:: PMC1134064

Abstract Article PDF–712K

Select item 26824938.

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Sekar Kathiresan, Olle Melander, Candace Guiducci, Aarti Surti, Noël P Burtt, Mark J Rieder, Gregory M Cooper, Charlotta Roos, Benjamin F Voight, Aki S Havulinna, Björn Wahlstrand, Thomas Hedner, Dolores Corella, E Shyong Tai, Jose M Ordovas, Göran Berglund, Erkki Vartiainen, Pekka Jousilahti, Bo Hedblad, Marja-Riitta Taskinen, Christopher Newton-Cheh, Veikko Salomaa, Leena Peltonen, Leif Groop, David M Altshuler, Marju Orho-Melander

Nat Genet. Author manuscript; available in PMC 2009 May 14.

Published in final edited form as: Nat Genet. 2008 Feb; 40(2): 189–197. Published online 2008 Jan 13. doi: 10.1038/ng.75

Correction in:: volume 40 on page 1384

PMCID:: PMC2682493

Abstract Article PDF–312K

Select item 93459699.

Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth

Rossella Delle Donne, Rosa Iannucci, Laura Rinaldi, Luca Roberto, Maria A. Oliva, Emanuela Senatore, Domenica Borzacchiello, Luca Lignitto, Giorgio Giurato, Francesca Rizzo, Assunta Sellitto, Francesco Chiuso, Salvatore Castaldo, Giovanni Scala, Virginia Campani, Valeria Nele, Giuseppe De Rosa, Chiara D’Ambrosio, Corrado Garbi, Andrea Scaloni, Alessandro Weisz, Concetta Ambrosino, Antonella Arcella, Antonio Feliciello

Commun Biol. 2022; 5: 780. Published online 2022 Aug 2. doi: 10.1038/s42003-022-03639-8

Correction in:: Commun Biol. 2024; 7: 1411.

PMCID:: PMC9345969

Abstract Article PDF–2.3M

Select item 629714110.

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage

Ryotaro Nishi, Paul W. G. Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Tom L. Blundell, Benedikt M. Kessler

Sci Rep. 2018; 8: 17891. Published online 2018 Dec 17. doi: 10.1038/s41598-018-36235-0

PMCID:: PMC6297141

Abstract Article PDF–2.6M

Select item 838674011.

Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy

Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda

Autophagy. 2021; 17(8): 2011–2036. Published online 2021 Jan 26. doi: 10.1080/15548627.2021.1874133

PMCID:: PMC8386740

Abstract Article PDF–13M

Select item 293164512.

Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population

B. Fontaine-Bisson, F. Renström, O. Rolandsson, The MAGIC investigators, F. Payne, G. Hallmans, I. Barroso, P. W. Franks

Diabetologia. 2010; 53(10): 2155–2162. Published online 2010 Jun 23. doi: 10.1007/s00125-010-1792-y

PMCID:: PMC2931645

Abstract Article PDF–688K

Select item 460561013.

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome

Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin

PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994

PMCID:: PMC4605610

Abstract Article PDF–6.8M

Select item 662002814.

Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality

Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St-Germain, Lauren E. Heese, Grace Egan, Vivian R. Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, John Man Chun Ma, Andrew B. Leber, Mark D. Minden, Walid Houry, Hagop Kantarjian, Martin Stogniew, Brian Raught, Emil F. Pai, Aaron D. Schimmer, Michael Andreeff

Cancer Cell. Author manuscript; available in PMC 2020 May 13.

Published in final edited form as: Cancer Cell. 2019 May 13; 35(5): 721–737.e9. Published online 2019 May 2. doi: 10.1016/j.ccell.2019.03.014

PMCID:: PMC6620028

Abstract Article PDF–2.9M

Select item 729517915.

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome

Gerald Dayebgadoh, Mihaela E. Sardiu, Laurence Florens, Michael P. Washburn

J Proteome Res. Author manuscript; available in PMC 2020 Jun 15.

Published in final edited form as: J Proteome Res. 2019 Sep 6; 18(9): 3479–3491. Published online 2019 Aug 9. doi: 10.1021/acs.jproteome.9b00373

PMCID:: PMC7295179

Abstract Article PDF–2.6M

Select item 764586316.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 764232717.

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner

Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0

PMCID:: PMC7642327

Abstract Article PDF–12M

Select item 302349418.

RioK1, a New Interactor of Protein Arginine Methyltransferase 5 (PRMT5), Competes with pICln for Binding and Modulates PRMT5 Complex Composition and Substrate Specificity

Gernot Guderian, Christoph Peter, Julia Wiesner, Albert Sickmann, Klaus Schulze-Osthoff, Utz Fischer, Matthias Grimmler

J Biol Chem. 2011 Jan 21; 286(3): 1976–1986. Published online 2010 Nov 16. doi: 10.1074/jbc.M110.148486

PMCID:: PMC3023494

Abstract Article PDF–4.1M

Select item 361021419.

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

Gaëlle Blandin, Sylvie Marchand, Karine Charton, Nathalie Danièle, Evelyne Gicquel, Jean-Baptiste Boucheteil, Azéddine Bentaib, Laetitia Barrault, Daniel Stockholm, Marc Bartoli, Isabelle Richard

Skelet Muscle. 2013; 3: 3. Published online 2013 Feb 15. doi: 10.1186/2044-5040-3-3

PMCID:: PMC3610214

Abstract Article PDF–1.7M

Select item 985197320.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

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