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Select item 101544221.

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification

Ozge Saatci, Ozge Akbulut, Metin Cetin, Vitali Sikirzhytski, Meral Uner, Deniz Lengerli, Elizabeth C. O’Quinn, Martin J. Romeo, Burcu Caliskan, Erden Banoglu, Sercan Aksoy, Aysegul Uner, Ozgur Sahin

Cell Death Differ. 2023 May; 30(5): 1305–1319. Published online 2023 Mar 2. doi: 10.1038/s41418-023-01140-1

PMCID:: PMC10154422

Abstract Article PDF–7.4M

Select item 92883352.

High Expression of TACC3 Is Associated with the Poor Prognosis and Immune Infiltration in Lung Adenocarcinoma Patients

Yan Chen, Min Zhou, Xuyu Gu, Longfei Wang, Cailian Wang

Dis Markers. 2022; 2022: 8789515. Published online 2022 Jul 9. doi: 10.1155/2022/8789515

PMCID:: PMC9288335

Abstract Article PDF–4.7M

Select item 82103873.

Transforming acidic coiled-coil protein-3: a novel marker for differential diagnosis and prognosis prediction in endocervical adenocarcinoma

Yan-Lin Wen, Shu-Mei Yan, Wei Wei, Xia Yang, Shi-Wen Zhang, Jing-Ping Yun, Li-Li Liu, Rong-Zhen Luo

Mol Med. 2021; 27: 60. Published online 2021 Jun 10. doi: 10.1186/s10020-021-00298-z

PMCID:: PMC8210387

Abstract Article PDF–3.8M

Select item 80349114.

TACC3 is a prognostic biomarker for kidney renal clear cell carcinoma and correlates with immune cell infiltration and T cell exhaustion

Xiaoyan Fan, Boyi Liu, Zhiyu Wang, Dongwei He

Aging (Albany NY) 2021 Mar 31; 13(6): 8541–8562. Published online 2021 Mar 10. doi: 10.18632/aging.202668

PMCID:: PMC8034911

Abstract Article PDF–2.0M

Select item 78445985.

Knockdown of TACC3 Inhibits the Proliferation and Invasion of Human Renal Cell Carcinoma Cells

Feng Guo, Yaquan Liu

Oncol Res. 2018; 26(2): 183–189. Published online 2018 Mar 5. doi: 10.3727/096504017X14837020772250

PMCID:: PMC7844598

Abstract Article PDF–1.4M

Select item 77319836.

Investigating the impact of the phosphorylation status of tyrosine residues within the TACC domain of TACC3 on microtubule behavior during axon growth and guidance

Burcu Erdogan, Riley M. St. Clair, Garrett M. Cammarata, Timothy Zaccaro, Bryan A. Ballif, Laura Anne Lowery

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2021 Jul 6.

Published in final edited form as: Cytoskeleton (Hoboken). 2020 Jul; 77(7): 277–291. Published online 2020 Jul 6. doi: 10.1002/cm.21622

PMCID:: PMC7731983

Abstract Article PDF–2.5M

Select item 69808317.

TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells

Colleen Furey, Vladimir Jovasevic, Derek Walsh

Cell Rep. Author manuscript; available in PMC 2020 Jan 24.

Published in final edited form as: Cell Rep. 2020 Jan 7; 30(1): 269–283.e6. doi: 10.1016/j.celrep.2019.12.025

PMCID:: PMC6980831

Abstract Article PDF–2.5M

Select item 62598068.

Elevated Expression of Transforming Acidic Coiled-Coil Containing Protein 3 (TACC3) Is Associated With a Poor Prognosis in Osteosarcoma

Kotaro Matsuda, Hiroaki Miyoshi, Koji Hiraoka, Tetsuya Hamada, Kazutaka Nakashima, Naoto Shiba, Koichi Ohshima

Clin Orthop Relat Res. 2018 Sep; 476(9): 1848–1855. Published online 2018 Jul 20. doi: 10.1097/CORR.0000000000000379

PMCID:: PMC6259806

Abstract Article PDF–564K

Select item 58977749.

Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix

Selena G Burgess, Manjeet Mukherjee, Sarah Sabir, Nimesh Joseph, Cristina Gutiérrez‐Caballero, Mark W Richards, Nicolas Huguenin‐Dezot, Jason W Chin, Eileen J Kennedy, Mark Pfuhl, Stephen J Royle, Fanni Gergely, Richard Bayliss

EMBO J. 2018 Apr 13; 37(8): e97902. Published online 2018 Mar 6. doi: 10.15252/embj.201797902

PMCID:: PMC5897774

Abstract Article PDF–3.3M

Select item 568559910.

Clinicopathological and prognostic value of transforming acidic coiled-coil-containing protein 3 (TACC3) expression in soft tissue sarcomas

Kotaro Matsuda, Hiroaki Miyoshi, Koji Hiraoka, Shintaro Yokoyama, Toshiaki Haraguchi, Toshihiro Hashiguchi, Tetsuya Hamada, Naoto Shiba, Koichi Ohshima

PLoS One. 2017; 12(11): e0188096. Published online 2017 Nov 14. doi: 10.1371/journal.pone.0188096

PMCID:: PMC5685599

Abstract Article PDF–11M

Select item 557744611.

FGFR3–TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindle

Sourav Sarkar, Ellis L. Ryan, Stephen J. Royle

Open Biol. 2017 Aug; 7(8): 170080. Published online 2017 Aug 30. doi: 10.1098/rsob.170080

PMCID:: PMC5577446

Abstract Article PDF–1.1M

Select item 547453812.

Association between the TACC3 rs798766 Polymorphism and Risk of Urinary Bladder Cancer: A Synthesis Based on Current Evidence

Xiang-Yu Meng, Ming-Jun Shi, Jia-Feng Chen, Yi Liao, Bang-Wang Hu, Ahmed Hireche

Dis Markers. 2017; 2017: 7850708. Published online 2017 Jun 5. doi: 10.1155/2017/7850708

PMCID:: PMC5474538

Abstract Article PDF–759K

Select item 544862613.

SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib

Nobumichi Ohoka, Katsunori Nagai, Norihito Shibata, Takayuki Hattori, Hiroshi Nara, Nobuo Cho, Mikihiko Naito

Cancer Sci. 2017 May; 108(5): 1032–1041. Published online 2017 Apr 26. doi: 10.1111/cas.13198

PMCID:: PMC5448626

Abstract Article PDF–2.6M

Select item 537248714.

Overexpression of Transforming Acidic Coiled Coil‑Containing Protein 3 Reflects Malignant Characteristics and Poor Prognosis of Glioma

Ying Sun, Yu Tian, Guang-Zhi Wang, Shi-Hong Zhao, Bo Han, Yong-Li Li, Chuan-Lu Jiang

Int J Mol Sci. 2017 Mar; 18(3): 235. Published online 2017 Mar 4. doi: 10.3390/ijms18030235

PMCID:: PMC5372487

Abstract Article PDF–8.5M

Select item 534275115.

TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anti-cancer molecular drug target for HDAC inhibitors

Jun-chuang He, Wei Yao, Jian-ming Wang, Peter Schemmer, Yan Yang, Yan Liu, Ya-wei Qian, Wei-peng Qi, Jian Zhang, Qi Shen, Tao Yang

Oncotarget. 2016 Nov 15; 7(46): 75441–75456. Published online 2016 Sep 26. doi: 10.18632/oncotarget.12254

PMCID:: PMC5342751

Abstract Article PDF–9.8M

Select item 517310316.

TACC3 promotes colorectal cancer tumourigenesis and correlates with poor prognosis

Yong Du, Lili Liu, Chenliang Wang, Bohua Kuang, Shumei Yan, Aijun Zhou, Chuangyu Wen, Junxiong Chen, Yue Wu, Xiangling Yang, Guokai Feng, Bin Liu, Aikichi Iwamoto, Musheng Zeng, Jianping Wang, Xing Zhang, Huanliang Liu

Oncotarget. 2016 Jul 5; 7(27): 41885–41897. Published online 2016 May 26. doi: 10.18632/oncotarget.9628