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Items: 1 to 20 of 136

1.
Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function
Kreetta Hämäläinen, Päivi Hirvensalo, Mikko Neuvonen, Aleksi Tornio, Janne T. Backman, Marko Lehtonen, Mikko Niemi
Clin Transl Sci. 2024 Mar; 17(3): e13773. Published online 2024 Mar 22. doi: 10.1111/cts.13773
PMCID:
PMC10958181
AbstractArticlePDF–1010K
2.
The impact of SLCO1B1 rs4149056 on LDL-C target achievement after lipid lowering therapy optimization in men and women with familial hypercholesterolemia
Giosiana Bosco, Francesco Di Giacomo Barbagallo, Maurizio Di Marco, Nicoletta Miano, Sabrina Scilletta, Salvatore Spampinato, Alessio Vitale, Federica Di Bella, Maria Montalbano, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Agostino Milluzzo, Antonino Di Pino, Lucia Frittitta, Francesco Purrello, Salvatore Piro, Roberto Scicali
Front Endocrinol (Lausanne) 2024; 15: 1346152. Published online 2024 Feb 8. doi: 10.3389/fendo.2024.1346152
PMCID:
PMC10885347
AbstractArticlePDF–640K
3.
Cryo-EM structures of human organic anion transporting polypeptide OATP1B1
Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang
Cell Res. 2023 Dec; 33(12): 940–951. Published online 2023 Sep 6. doi: 10.1038/s41422-023-00870-8
PMCID:
PMC10709409
AbstractArticlePDF–6.3M
4.
Association between SLCO1B1 genetic polymorphisms and bleeding risk in patients treated with edoxaban
Ji Min Han, Eun Jeong Jang, Jeong Yee, Tae-Jin Song, Dong-Hyeok Kim, Junbeom Park, Hye Sun Gwak
Sci Rep. 2023; 13: 15967. Published online 2023 Sep 25. doi: 10.1038/s41598-023-43179-7
PMCID:
PMC10520058
AbstractArticlePDF–1.0M
5.
SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort
Emma F. Magavern, David A. van Heel, Genes & Health Research Team, Damian Smedley, Mark J. Caulfield
Pharmacogenomics J. 2023; 23(5): 134–139. Published online 2023 May 23. doi: 10.1038/s41397-023-00307-w
PMCID:
PMC10506906
AbstractArticlePDF–834K
6.
Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder
Katja Häkkinen, Wilma Kiander, Heidi Kidron, Markku Lähteenvuo, Lea Urpa, Jonne Lintunen, Kati-Sisko Vellonen, Seppo Auriola, Minna Holm, Kaisla Lahdensuo, Olli Kampman, Erkki Isometsä, Tuula Kieseppä, Jouko Lönnqvist, Jaana Suvisaari, Jarmo Hietala, Jari Tiihonen, Aarno Palotie, Ari V. Ahola-Olli, Mikko Niemi
Mol Pharm. 2023 Mar 6; 20(3): 1500–1508. Published online 2023 Feb 13. doi: 10.1021/acs.molpharmaceut.2c00715
PMCID:
PMC9996821
AbstractArticlePDF–3.3M
7.
Effects of the SLCO1B1 A388G single nucleotide polymorphism on the development, clinical parameters, treatment, and survival of multiple myeloma cases in a Polish population
Katarzyna Michalska, Ewa Balcerczak, Agnieszka Jeleń, Lias Saed, Jacek Pietrzak, Marta Żebrowska-Nawrocka
Mol Biol Rep. 2023; 50(2): 1447–1458. Published online 2022 Dec 7. doi: 10.1007/s11033-022-08162-x
PMCID:
PMC9889417
AbstractArticlePDF–956K
8.
Association between single nucleotide polymorphism SLCO1B1 gene and simvastatin pleiotropic effects measured through flow-mediated dilation endothelial function parameters
Andrianto, Mia Puspitasari, Meity Ardiana, Ivana Purnama Dewi, Khubay Alvia Shonafi, Louisa Fadjri Kusuma Wardhani, Ricardo Adrian Nugraha
Ther Adv Cardiovasc Dis. 2022; 16: 17539447221132367. Published online 2022 Oct 31. doi: 10.1177/17539447221132367
PMCID:
PMC9629567
AbstractArticlePDF–509K
9.
SLCO1B1*5 Allele Is Associated With Atorvastatin Discontinuation and Adverse Muscle Symptoms in the Context of Routine Care
Deepak Voora, Jordan Baye, Adam McDermaid, Smitha Narayana Gowda, Russell A. Wilke, Anna Nicole Myrmoe, Catherine Hajek, Eric A. Larson
Clin Pharmacol Ther. 2022 May; 111(5): 1075–1083. Published online 2022 Feb 5. doi: 10.1002/cpt.2527
PMCID:
PMC9303592
AbstractArticlePDF–380K
10.
Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans
Mikko Neuvonen, Aleksi Tornio, Päivi Hirvensalo, Janne T. Backman, Mikko Niemi
Clin Pharmacol Ther. 2021 Dec; 110(6): 1622–1632. Published online 2021 Oct 15. doi: 10.1002/cpt.2429
PMCID:
PMC9292572
AbstractArticlePDF–708K
11.
SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease
Rishi S. Mehta, Zachary L. Taylor, Lisa J. Martin, Michael J. Rosen, Laura B. Ramsey
Clin Transl Sci. 2022 Jan; 15(1): 63–69. Published online 2021 Aug 23. doi: 10.1111/cts.13130
PMCID:
PMC8742639
AbstractArticlePDF–343K
12.
The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality
Wilma Kiander, Kati-Sisko Vellonen, Melina M. Malinen, Mikko Gynther, Marja Hagström, Madhushree Bhattacharya, Seppo Auriola, Jan B. Koenderink, Heidi Kidron
Pharm Res. 2021; 38(10): 1663–1675. Published online 2021 Oct 13. doi: 10.1007/s11095-021-03107-8
PMCID:
PMC8602229
AbstractArticlePDF–1.9M
13.
OATP1B1 Plays an Important Role in the Transport and Treatment Efficacy of Sorafenib in Hepatocellular Carcinoma
Jinhua Wen, Menghua Zhao
Dis Markers. 2021; 2021: 9711179. Published online 2021 Sep 26. doi: 10.1155/2021/9711179
PMCID:
PMC8550862
AbstractArticlePDF–2.3M
14.
Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant
Melissa Merkel, Christina Schneider, Robin Greinert, Alexander Zipprich, Cristina Ripoll, Frank Lammert, Matthias C. Reichert
Hepatol Commun. 2021 Oct; 5(10): 1755–1766. Published online 2021 Aug 28. doi: 10.1002/hep4.1753
PMCID:
PMC8485882
AbstractArticlePDF–266K
15.
Characterization of plasma membrane localization and phosphorylation status of organic anion transporting polypeptide (OATP) 1B1 c.521 T>C nonsynonymous single-nucleotide polymorphism
Alexandra Crowe, Wei Zheng, Jonathan Miller, Sonia Pahwa, Khondoker Alam, Kar-Ming Fung, Erin Rubin, Feng Yin, Kai Ding, Wei Yue
Pharm Res. Author manuscript; available in PMC 2021 Sep 22.
Published in final edited form as: Pharm Res. 2019 May 15; 36(7): 101. Published online 2019 May 15. doi: 10.1007/s11095-019-2634-3
PMCID:
PMC8456979
AbstractArticlePDF–1.5M
16.
Effect of SLCO1B1 T521C on Statin-related Myotoxicity with Use of Lovastatin and Atorvastatin
Brian Lu, Laura Sun, Manuel Seraydarian, Thomas J. Hoffmann, Marisa W. Medina, Carlos Iribarren, Ronald M. Krauss, Neil Risch, Akinyemi Oni-Orisan
Clin Pharmacol Ther. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Sep; 110(3): 733–740. Published online 2021 Jul 23. doi: 10.1002/cpt.2337
Correction in:
Clin Pharmacol Ther. 2023 Feb 25
PMCID:
PMC8376784
AbstractArticlePDF–421K
17.
A systematic review and meta-analysis of genotype-based and individualized data analysis of SLCO1B1 gene and statin-induced myopathy
Saowalak Turongkaravee, Jiraphun Jittikoon, Thitiya Lukkunaprasit, Sermsiri Sangroongruangsri, Usa Chaikledkaew, Ammarin Thakkinstian
Pharmacogenomics J. 2021; 21(3): 296–307. Published online 2021 Feb 19. doi: 10.1038/s41397-021-00208-w
PMCID:
PMC8159730
AbstractArticlePDF–707K
18.
Association of SLCO1B1 c.521T>C (rs4149056) with Discontinuation of Atorvastatin Due to Statin-Associated Muscle Symptoms
DEREK W. LINSKEY, JOSEPH D. ENGLISH, DANIEL A. PERRY, HEATHER M. OCHS-BALCOM, CHANGXING MA, PAUL J. ISACKSON, GEORGIRENE D. VLADUTIU, JASMINE A. LUZUM
Pharmacogenet Genomics. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Pharmacogenet Genomics. 2020 Dec; 30(9): 208–211. doi: 10.1097/FPC.0000000000000412
PMCID:
PMC8062056
AbstractArticlePDF–93K
19.
SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function
Lingxin Zhang, Vivekananda Sarangi, Ming-Fen Ho, Irene Moon, Krishna R. Kalari, Liewei Wang, Richard M. Weinshilboum
Drug Metab Dispos. 2021 May; 49(5): 395–404. Published online 2021 May. doi: 10.1124/dmd.120.000264
PMCID:
PMC8042483
AbstractArticlePDF–1.0M
20.
Intestinal P-gp and Putative Hepatic OATP1B Induction: ITC Perspective on Drug Development Implications
Maciej J. Zamek-Gliszczynski, Mitesh Patel, Xinning Yang, Justin D. Lutz, Xiaoyan Chu, Kim L. R. Brouwer, Yurong Lai, Caroline A. Lee, Sibylle Neuhoff, Mary F. Paine, Yuichi Sugiyama, Kunal S. Taskar, Aleksandra Galetin
Clin Pharmacol Ther. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Jan; 109(1): 55–64. Published online 2020 Jul 9. doi: 10.1002/cpt.1916
PMCID:
PMC8020731
AbstractArticlePDF–387K

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