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Select item 110410181.

KHDRBS1 as a novel prognostic signaling biomarker influencing hepatocellular carcinoma cell proliferation, migration, immune microenvironment, and drug sensitivity

Rui Fan, Fahui Liu, Qiming Gong, Donghua Liu, Shihang Tang, Dongyan Shen

Front Immunol. 2024; 15: 1393801. Published online 2024 Apr 10. doi: 10.3389/fimmu.2024.1393801

PMCID:: PMC11041018

Abstract Article PDF–29M

Select item 110161292.

Sam68 is a druggable vulnerability point in cancer stem cells

Amanda Mendes da Silva, Veronika Yevdokimova, Yannick D. Benoit

Cancer Metastasis Rev. 2024; 43(1): 441–456. Published online 2023 Oct 4. doi: 10.1007/s10555-023-10145-8

PMCID:: PMC11016129

Abstract Article PDF–1.6M

Select item 98251553.

Cdk1-mediated threonine phosphorylation of Sam68 modulates its RNA binding, alternative splicing activity and cellular functions

Idir Malki, Inara Liepina, Nora Kogelnik, Hollie Watmuff, Sue Robinson, Adam Lightfoot, Oksana Gonchar, Andrew Bottrill, Andrew M Fry, Cyril Dominguez

Nucleic Acids Res. 2022 Dec 9; 50(22): 13045–13062. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1181

PMCID:: PMC9825155

Abstract Article PDF–2.6M

Select item 94969174.

Decreased Expression of Sam68 Is Associated with Insulin Resistance in Granulosa Cells from PCOS Patients

Teresa Vilariño-García, Pilar Guadix, Mónica Dorado-Silva, Pascual Sánchez-Martín, Antonio Pérez-Pérez, Víctor Sánchez-Margalet

Cells. 2022 Sep; 11(18): 2821. Published online 2022 Sep 9. doi: 10.3390/cells11182821

PMCID:: PMC9496917

Abstract Article PDF–1.8M

Select item 66686495.

A comprehensive study on genome-wide coexpression network of KHDRBS1/Sam68 reveals its cancer and patient-specific association

B. Sumithra, Urmila Saxena, Asim Bikas Das

Sci Rep. 2019; 9: 11083. Published online 2019 Jul 31. doi: 10.1038/s41598-019-47558-x

PMCID:: PMC6668649

Abstract Article PDF–2.4M

Select item 66001836.

Sam68 Promotes Hepatitis C Virus Replication by Interaction with Stem-Loop 2 of Viral 5′ Untranslated Region

Yuwen Qin, Zhen Xun, Yanxia Guo, Shengwen Chen, Haizhen Zhu

J Virol. 2019 Jul 15; 93(14): e00693-19. Prepublished online 2019 May 8. Published online 2019 Jun 28. doi: 10.1128/JVI.00693-19

PMCID:: PMC6600183

Abstract Article PDF–1.9M

Select item 50311687.

Sam68 is Overexpressed in Epithelial Ovarian Cancer and Promotes Tumor Cell Proliferation

Lijuan Dong, Hailuo Che, Mingmei Li, Xuepeng Li

Med Sci Monit. 2016; 22: 3248–3750. Published online 2016 Sep 13. doi: 10.12659/MSM.899980

PMCID:: PMC5031168

Abstract Article PDF–1.4M

Select item 49667778.

Sam68 reduces cisplatin-induced apoptosis in tongue carcinoma

Shuwei Chen, Huan Li, Shimin Zhuang, Ji Zhang, Fan Gao, Xidi Wang, WenKuan Chen, Ming Song

J Exp Clin Cancer Res. 2016; 35: 123. Published online 2016 Jul 29. doi: 10.1186/s13046-016-0390-3

PMCID:: PMC4966777

Abstract Article PDF–3.5M

Select item 46890639.

Analysis of the interaction between host factor Sam68 and viral elements during foot-and-mouth disease virus infections

Devendra K. Rai, Paul Lawrence, Anna Kloc, Elizabeth Schafer, Elizabeth Rieder

Virol J. 2015; 12: 224. Published online 2015 Dec 23. doi: 10.1186/s12985-015-0452-8

PMCID:: PMC4689063

Abstract Article PDF–2.0M

Select item 457788310.

Nuclear Protein Sam68 Interacts with the Enterovirus 71 Internal Ribosome Entry Site and Positively Regulates Viral Protein Translation

Hua Zhang, Lei Song, Haolong Cong, Po Tien

J Virol. 2015 Oct 1; 89(19): 10031–10043. Published online 2015 Jul 22. doi: 10.1128/JVI.01677-15

PMCID:: PMC4577883

Abstract Article PDF–2.3M

Select item 452992511.

SAM68: Signal Transduction and RNA Metabolism in Human Cancer

Paola Frisone, Davide Pradella, Anna Di Matteo, Elisa Belloni, Claudia Ghigna, Maria Paola Paronetto

Biomed Res Int. 2015; 2015: 528954. Published online 2015 Jul 26. doi: 10.1155/2015/528954

PMCID:: PMC4529925

Abstract Article PDF–1.2M

Select item 442587312.

Utility of SAM68 in the progression and prognosis for bladder cancer

Zhiling Zhang, Chunping Yu, Yonghong Li, Lijuan Jiang, Fangjian Zhou

BMC Cancer. 2015; 15: 364. Published online 2015 May 6. doi: 10.1186/s12885-015-1367-x

PMCID:: PMC4425873

Abstract Article PDF–3.0M

Select item 438005813.

Sam68 is cleaved by caspases under apoptotic cell death induced by ionizing radiation

Seong-Jun Cho, Moo Hyun Choi, Seon Young Nam, Ji Young Kim, Cha Soon Kim, Suhkneung Pyo, Kwang Hee Yang

J Radiat Res. 2015 Mar; 56(2): 287–293. Published online 2015 Feb 8. doi: 10.1093/jrr/rru113

PMCID:: PMC4380058

Abstract Article PDF–340K

Select item 397199414.

Mechanisms of HGF/Met Signaling to Brk and Sam68 in Breast Cancer Progression

Alessia Locatelli, Kristopher A. Lofgren, Andrea R. Daniel, Nancy E. Castro, Carol A. Lange

Horm Cancer. 2012 Apr; 3(1-2): 14–25. Published online 2011 Nov 29. doi: 10.1007/s12672-011-0097-z

PMCID:: PMC3971994

Abstract Article PDF–458K

Select item 387605315.

Role of Sam68 in Post-Transcriptional Gene Regulation

Flora Sánchez-Jiménez, Víctor Sánchez-Margalet

Int J Mol Sci. 2013 Dec; 14(12): 23402–23419. Published online 2013 Nov 28. doi: 10.3390/ijms141223402

PMCID:: PMC3876053

Abstract Article PDF–192K

Select item 295344216.

Sam68 regulates EMT through alternative splicing–activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene

Cristina Valacca, Serena Bonomi, Emanuele Buratti, Simona Pedrotti, Francisco Ernesto Baralle, Claudio Sette, Claudia Ghigna, Giuseppe Biamonti

J Cell Biol. 2010 Oct 4; 191(1): 87–99. doi: 10.1083/jcb.201001073

PMCID:: PMC2953442

Abstract Article PDF–2.5M

Select item 293791617.

Structural Basis for Homodimerization of the Src-associated during Mitosis, 68-kDa Protein (Sam68) Qua1 Domain

N. Helge Meyer, Konstantinos Tripsianes, Michelle Vincendeau, Tobias Madl, Fatiha Kateb, Ruth Brack-Werner, Michael Sattler

J Biol Chem. 2010 Sep 10; 285(37): 28893–28901. Published online 2010 Jul 6. doi: 10.1074/jbc.M110.126185

PMCID:: PMC2937916

Abstract Article PDF–2.2M

Select item 285746418.

Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

Chantal Sellier, Frédérique Rau, Yilei Liu, Flora Tassone, Renate K Hukema, Renata Gattoni, Anne Schneider, Stéphane Richard, Rob Willemsen, David J Elliott, Paul J Hagerman, Nicolas Charlet-Berguerand

EMBO J. 2010 Apr 7; 29(7): 1248–1261. Published online 2010 Feb 25. doi: 10.1038/emboj.2010.21

PMCID:: PMC2857464

Abstract Article PDF–1.5M

Select item 987255319.

The transcriptional terminator XRN2 and the RNA-binding protein Sam68 link alternative polyadenylation to cell cycle progression in prostate cancer

Marco Pieraccioli, Cinzia Caggiano, Luca Mignini, Chuwei Zhong, Gabriele Babini, Rossano Lattanzio, Savino Di Stasi, Bin Tian, Claudio Sette, Pamela Bielli

Nat Struct Mol Biol. Author manuscript; available in PMC 2023 Jan 24.

Published in final edited form as: Nat Struct Mol Biol. 2022 Nov; 29(11): 1101–1112. Published online 2022 Nov 7. doi: 10.1038/s41594-022-00853-0

PMCID:: PMC9872553

Abstract Article PDF–5.1M

Select item 947895320.

High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma

Takuya Komiyama, Takeshi Kuroshima, Takehito Sugasawa, Shin-Ichiro Fujita, Yuta Ikami, Hideaki Hirai, Fumihiko Tsushima, Yasuyuki Michi, Kou Kayamori, Fumihiro Higashino, Hiroyuki Harada

Oncol Rep. 2022 Oct; 48(4): 183. Published online 2022 Sep 7. doi: 10.3892/or.2022.8398