PMC Links for Gene (Select 10735) - PMC

Bahga Katamesh, Ahmad Nanaa, Rong He, David Viswanatha, Phuong Nguyen, Patricia Greipp, Kurt Bessonen, Naseema Gangat, Kebede Begna, Abhishek Mangaonkar, Mrinal Patnaik, William J. Hogan, Ayalew Tefferi, Mark Litzow, Mithun Vinod Shah, Cecilia Arana Yi, James Foran, Talha Badar, Hassan B. Alkhateeb, Aref Al-Kali

Blood Adv. 2023 Apr 25; 7(8): 1351–1355. Published online 2022 Dec 9. doi: 10.1182/bloodadvances.2022007937

PMCID:: PMC10139934

Article PDF–301K

Select item 98738114.

Alterations of cohesin complex genes in acute myeloid leukemia: differential co-mutations, clinical presentation and impact on outcome

Jan-Niklas Eckardt, Sebastian Stasik, Christoph Röllig, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Volker Kunzmann, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Regina Herbst, Mathias Hänel, Maher Hanoun, Ulrich Kaiser, Martin Kaufmann, Zdenek Rácil, Jiri Mayer, Tiago Cerqueira, Frank Kroschinsky, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow, Uwe Platzbecker, Claudia D. Baldus, Johannes Schetelig, Timo Siepmann, Martin Bornhäuser, Jan Moritz Middeke, Christian Thiede

Blood Cancer J. 2023 Dec; 13(1): 18. Published online 2023 Jan 24. doi: 10.1038/s41408-023-00790-1

PMCID:: PMC9873811

Abstract Article PDF–2.3M

Select item 97269325.

Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group

David S. Shulman, Sonja Chen, David Hall, Anwesha Nag, Aaron R. Thorner, Stephen L. Lessnick, Kimberly Stegmaier, Katherine A. Janeway, Steven G. DuBois, Mark D. Krailo, Donald A. Barkauskas, Alanna J. Church, Brian D. Crompton

Br J Cancer. 2022 Dec 7; 127(12): 2220–2226. Published online 2022 Oct 11. doi: 10.1038/s41416-022-01977-2

PMCID:: PMC9726932

Abstract Article PDF–470K

Select item 95837566.

STAG2 Expression is Associated with Adverse Survival Outcomes and Regulates Cell Phenotype in Muscle-invasive Bladder Cancer

Sarah R. Athans, Nithya Krishnan, Swathi Ramakrishnan, Eduardo Cortes Gomez, Sofía Lage-Vickers, Monika Rak, Zara I. Kazmierczak, Joyce Ellen Ohm, Kristopher Attwood, Jianmin Wang, Anna Woloszynska

Cancer Res Commun. 2022 Oct; 2(10): 1129–1143. Published online 2022 Oct 6. doi: 10.1158/2767-9764.CRC-22-0155

PMCID:: PMC9583756

Abstract Article PDF–12M

Select item 84083477.

Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2

Melanie L Bailey, David Tieu, Andrea Habsid, Amy Hin Yan Tong, Katherine Chan, Jason Moffat, Philip Hieter

Life Sci Alliance. 2021 Nov; 4(11): e202101083. Published online 2021 Aug 30. doi: 10.26508/lsa.202101083

PMCID:: PMC8408347

Abstract Article PDF–2.2M

Select item 74694208.

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

James S. Smith, Katrina M. Lappin, Stephanie G. Craig, Fabio G. Liberante, Clare M. Crean, Simon S. McDade, Alexander Thompson, Ken I. Mills, Kienan I. Savage

J Transl Med. 2020; 18: 339. Published online 2020 Sep 3. doi: 10.1186/s12967-020-02500-y

PMCID:: PMC7469420

Abstract Article PDF–9.9M

Select item 64599179.

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers

Gourish Mondal, Meredith Stevers, Benjamin Goode, Alan Ashworth, David A. Solomon

Nat Commun. 2019; 10: 1686. Published online 2019 Apr 11. doi: 10.1038/s41467-019-09659-z

PMCID:: PMC6459917

Abstract Article PDF–4.5M

Select item 639555810.

Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies

Bo Yuan, Juanita Neira, Davut Pehlivan, Teresa Santiago-Sim, Xiaofei Song, Jill Rosenfeld, Jennifer E. Posey, Vipulkumar Patel, Weihong Jin, Margaret P. Adam, Emma L. Baple, John Dean, Chin-To Fong, Scott E. Hickey, Louanne Hudgins, Eyby Leon, Suneeta Madan-Khetarpal, Lettie Rawlins, Cecilie F. Rustad, Asbjørg Stray-Pedersen, Kristian Tveten, Olivia Wenger, Jullianne Diaz, Laura Jenkins, Laura Martin, Marianne McGuire, Marguerite Pietryga, Linda Ramsdell, Leah Slattery, DDD Study, Farida Abid, Alison Bertuch, Dorothy Grange, LaDonna Immken, Christian P. Schaaf, Hilde Van Esch, Weimin Bi, Sau Wai Cheung, Amy M. Breman, Janice L. Smith, Chad Shaw, Andrew H. Crosby, Christine Eng, Yaping Yang, James R. Lupski, Rui Xiao, Pengfei Liu

Genet Med. Author manuscript; available in PMC 2019 Mar 7.

Published in final edited form as: Genet Med. 2019 Mar; 21(3): 663–675. Published online 2018 Aug 30. doi: 10.1038/s41436-018-0085-6

PMCID:: PMC6395558

Abstract Article PDF–370K

Select item 612522511.

STAG2 is a Biomarker for Prediction of Recurrence and Progression in Papillary Non-Muscle Invasive Bladder Cancer

Alana Lelo, Frederik Prip, Brent T. Harris, David Solomon, Deborah L. Berry, Krysta Chaldekas, Anagha Kumar, Jeffry Simko, Jørgen Bjerggaard Jensen, Pritish Bhattacharyya, Ciaran Mannion, Jung-Sik Kim, George Philips, Lars Dyrskjøt, Todd Waldman

Clin Cancer Res. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Clin Cancer Res. 2018 Sep 1; 24(17): 4145–4153. Published online 2018 Jun 28. doi: 10.1158/1078-0432.CCR-17-3244

PMCID:: PMC6125225

Abstract Article PDF–1.1M

Select item 564524012.

Loss of tumor suppressor STAG2 promotes telomere recombination and extends the replicative lifespan of normal human cells

Zharko Daniloski, Susan Smith

Cancer Res. Author manuscript; available in PMC 2018 Oct 15.

Published in final edited form as: Cancer Res. 2017 Oct 15; 77(20): 5530–5542. Published online 2017 Aug 17. doi: 10.1158/0008-5472.CAN-17-1260

PMCID:: PMC5645240

Abstract Article PDF–2.6M

Select item 498018013.

Cohesin Mutations in Human Cancer

Victoria K. Hill, Jung-Sik Kim, Todd Waldman

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Aug; 1866(1): 1–11. Published online 2016 May 17. doi: 10.1016/j.bbcan.2016.05.002

PMCID:: PMC4980180

Abstract Article PDF–612K

Select item 417949114.

STAG2 promotes error correction in mitosis by regulating kinetochore–microtubule attachments

Marianna Kleyman, Lilian Kabeche, Duane A. Compton

J Cell Sci. 2014 Oct 1; 127(19): 4225–4233. doi: 10.1242/jcs.151613

PMCID:: PMC4179491

Abstract Article

Select item 409178215.

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation

Andrew S. Brohl, David A. Solomon, Wendy Chang, Jianjun Wang, Young Song, Sivasish Sindiri, Rajesh Patidar, Laura Hurd, Li Chen, Jack F. Shern, Hongling Liao, Xinyu Wen, Julia Gerard, Jung-Sik Kim, Jose Antonio Lopez Guerrero, Isidro Machado, Daniel H. Wai, Piero Picci, Timothy Triche, Andrew E. Horvai, Markku Miettinen, Jun S. Wei, Daniel Catchpool, Antonio Llombart-Bosch, Todd Waldman, Javed Khan

PLoS Genet. 2014 Jul; 10(7): e1004475. Published online 2014 Jul 10. doi: 10.1371/journal.pgen.1004475

Correction in:: PLoS Genet. 2014 Aug; 10(8): e1004629.

PMCID:: PMC4091782

Abstract Article PDF–7.5M

Select item 395981116.

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

Claire F. Taylor, Fiona M. Platt, Carolyn D. Hurst, Helene H. Thygesen, Margaret A. Knowles

Hum Mol Genet. 2014 Apr 15; 23(8): 1964–1974. Published online 2013 Nov 22. doi: 10.1093/hmg/ddt589

PMCID:: PMC3959811

Abstract Article PDF–1.1M

Select item 387513017.

Frequent truncating mutations of STAG2 in bladder cancer

David A. Solomon, Jung-Sik Kim, Jolanta Bondaruk, Shahrokh F. Shariat, Zeng-Feng Wang, Abdel G. Elkahloun, Tomoko Ozawa, Julia Gerard, DaZhong Zhuang, Shizhen Zhang, Neema Navai, Arleen Siefker-Radtker, Joanna J. Phillips, Brian D. Robinson, Mark A. Rubin, Björn Volkmer, Richard Hautmann, Rainer Küfer, Pancras C. W. Hogendoorn, George Netto, Dan Theodorescu, C. David James, Bogdan Czerniak, Markku Miettinen, Todd Waldman

Nat Genet. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Nat Genet. 2013 Dec; 45(12): 1428–1430. Published online 2013 Oct 13. doi: 10.1038/ng.2800

PMCID:: PMC3875130

Abstract Article PDF–875K

Select item 385313518.

Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2 gene

Anna Djos, Susanne Fransson, Per Kogner, Tommy Martinsson

BMC Med Genet. 2013; 14: 102. Published online 2013 Oct 2. doi: 10.1186/1471-2350-14-102

PMCID:: PMC3853135

Abstract Article PDF–1.5M

Select item 384005219.

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy

Cristina Balbás-Martínez, Ana Sagrera, Enrique Carrillo-de-Santa-Pau, Julie Earl, Mirari Márquez, Miguel Vazquez, Eleonora Lapi, Francesc Castro-Giner, Sergi Beltran, Mònica Bayés, Alfredo Carrato, Juan C. Cigudosa, Orlando Domínguez, Marta Gut, Jesús Herranz, Núria Juanpere, Manolis Kogevinas, Xavier Langa, Elena López-Knowles, José A. Lorente, Josep Lloreta, David G. Pisano, Laia Richart, Daniel Rico, Rocío N. Salgado, Adonina Tardón, Stephen Chanock, Simon Heath, Alfonso Valencia, Ana Losada, Ivo Gut, Núria Malats, Francisco X. Real

Nat Genet. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Nat Genet. 2013 Dec; 45(12): 1464–1469. Published online 2013 Oct 13. doi: 10.1038/ng.2799

PMCID:: PMC3840052

Abstract Article PDF–1.4M

Select item 337433520.

Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

David A. Solomon, Taeyeon Kim, Laura A. Diaz-Martinez, Joshlean Fair, Abdel G. Elkahloun, Brent T. Harris, Jeffrey A. Toretsky, Steven A. Rosenberg, Neerav Shukla, Marc Ladanyi, Yardena Samuels, C. David James, Hongtao Yu, Jung-Sik Kim, Todd Waldman

Science. Author manuscript; available in PMC 2012 Jun 13.

Published in final edited form as: Science. 2011 Aug 19; 333(6045): 1039–1043. doi: 10.1126/science.1203619

PMCID:: PMC3374335

Abstract Article PDF–3.3M

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