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Select item 108615791.

SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice

Guohua Chen, Guoli Zhou, Lidong Zhai, Xun Bao, Nivedita Tiwari, Jing Li, Emilio Mottillo, Jian Wang

Commun Biol. 2024; 7: 173. Published online 2024 Feb 12. doi: 10.1038/s42003-024-05861-y

PMCID:: PMC10861579

Abstract Article PDF–4.8M

Select item 68316882.

Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders

Haruna Tani, Takayuki Mito, Vidya Velagapudi, Kaori Ishikawa, Moe Umehara, Kazuto Nakada, Anu Suomalainen, Jun-Ichi Hayashi

Sci Rep. 2019; 9: 16054. Published online 2019 Nov 5. doi: 10.1038/s41598-019-52372-6

PMCID:: PMC6831688

Abstract Article PDF–4.5M

Select item 115084033.

Serine Hydroxymethyltransferase 2 Deficiency in the Hematopoietic System Disrupts Erythropoiesis and Induces Anemia in Murine Models

Jisheng Li, Bowen Zhang, Yunqiao Li, Chuanli Liu, Xuan Tang, Jiahui Zhao, Xuetao Pei, Yanhua Li

Int J Mol Sci. 2024 Oct; 25(20): 11072. Published online 2024 Oct 15. doi: 10.3390/ijms252011072

PMCID:: PMC11508403

Abstract Article PDF–17M

Select item 109535814.

SHMT2 Mediates Small‐Molecule‐Induced Alleviation of Alzheimer Pathology Via the 5′UTR‐dependent ADAM10 Translation Initiation

Li Song, Qiu‐Ling Pan, Gui‐Feng Zhou, Sheng‐Wei Liu, Bing‐Lin Zhu, Pei‐Jia Lin, Xiao‐Tong Hu, Jing‐Si Zha, Yan Long, Biao Luo, Jian Chen, Ying Tang, Jing Tang, Xiao‐Jiao Xiang, Xiao‐Yong Xie, Xiao‐Juan Deng, Guo‐Jun Chen

Adv Sci (Weinh) 2024 Mar; 11(11): 2305260. Published online 2024 Jan 6. doi: 10.1002/advs.202305260

PMCID:: PMC10953581

Abstract Article PDF–11M

Select item 68857905.

Downregulating Serine Hydroxymethyltransferase 2 Deteriorates Hepatic Ischemia-Reperfusion Injury through ROS/JNK/P53 Signaling in Mice

Hao Wu, He Bai, Shigang Duan, Fangchao Yuan

Biomed Res Int. 2019; 2019: 2712185. Published online 2019 Nov 18. doi: 10.1155/2019/2712185

PMCID:: PMC6885790

Abstract Article PDF–5.0M

Select item 58193606.

Serine Catabolism by SHMT2 is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl tRNAs

Denise R. Minton, Minwoo Nam, Daniel J. McLaughlin, Jong Shin, Erol C. Bayraktar, Samantha W. Alvarez, Vladislav O. Sviderskiy, Thales Papagiannakopoulos, David M. Sabatini, Kıvanç Birsoy, Richard Possemato

Mol Cell. Author manuscript; available in PMC 2019 Feb 15.

Published in final edited form as: Mol Cell. 2018 Feb 15; 69(4): 610–621.e5. doi: 10.1016/j.molcel.2018.01.024

PMCID:: PMC5819360

Abstract Article PDF–1.8M

Select item 57651567.

Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal

Haruna Tani, Sakiko Ohnishi, Hiroshi Shitara, Takayuki Mito, Midori Yamaguchi, Hiromichi Yonekawa, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi

Sci Rep. 2018; 8: 425. Published online 2018 Jan 11. doi: 10.1038/s41598-017-18828-3

PMCID:: PMC5765156

Abstract Article PDF–1.5M

Select item 35457948.

Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice

Jessica Momb, Jordan P. Lewandowski, Joshua D. Bryant, Rebecca Fitch, Deborah R. Surman, Steven A. Vokes, Dean R. Appling

Proc Natl Acad Sci U S A. 2013 Jan 8; 110(2): 549–554. Published online 2012 Dec 24. doi: 10.1073/pnas.1211199110

PMCID:: PMC3545794

Abstract Article PDF–872K

Select item 26887539.

SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis

Donald D. Anderson, Patrick J. Stover

PLoS One. 2009; 4(6): e5839. Published online 2009 Jun 9. doi: 10.1371/journal.pone.0005839

PMCID:: PMC2688753

Abstract Article PDF–636K

Select item 854859610.

Liver and brain differential expression of one-carbon metabolism genes during ontogenesis

Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist

Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9

PMCID:: PMC8548596

Abstract Article PDF–1.3M

Select item 524740411.

Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import

Hyo-Jung Choo, Alicia Cutler, Franziska Rother, Michael Bader, Grace K. Pavlath

Stem Cells. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Stem Cells. 2016 Nov; 34(11): 2784–2797. Published online 2016 Aug 1. doi: 10.1002/stem.2467

PMCID:: PMC5247404

Abstract Article PDF–2.2M

Select item 619212112.

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao

Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z

PMCID:: PMC6192121

Abstract Article PDF–12M

Select item 579538813.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

Select item 31111914.

Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method

Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko

Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501

PMCID:: PMC311119

Abstract Article PDF–743K

Select item 629804015.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 277884416.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 948193317.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 18788518.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Abstract Article PDF–287K

Select item 30876319.

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller, Gregor Eichele

Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029

PMCID:: PMC308763

Abstract Article PDF–253K

Select item 1683320.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Abstract Article PDF–847K

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