PMC Links for Gene (Select 108071) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 202

<< First< Prev

Page of 11

Select item 108448901.

Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk

Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B. Fall, Danielle M. Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S. Lee

Cell Rep. Author manuscript; available in PMC 2024 Feb 6.

Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113595. Published online 2023 Dec 19. doi: 10.1016/j.celrep.2023.113595

PMCID:: PMC10844890

Abstract Article PDF–2.5M

Select item 107662402.

Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity

Jakob Hakon, Miriana J Quattromani, Carin Sjölund, Daniela Talhada, Byungchan Kim, Slavianka Moyanova, Federica Mastroiacovo, Luisa Di Menna, Roger Olsson, Elisabet Englund, Ferdinando Nicoletti, Karsten Ruscher, Adam Q Bauer, Tadeusz Wieloch

Brain. 2024 Jan; 147(1): 186–200. Published online 2023 Sep 1. doi: 10.1093/brain/awad293

PMCID:: PMC10766240

Abstract Article PDF–1.0M

Select item 106946563.

Amyloid-β_1-42 oligomers enhance mGlu₅R-dependent synaptic weakening via NMDAR activation and complement C5aR1 signaling

Ai Na Ng, Eric W. Salter, John Georgiou, Zuner A. Bortolotto, Graham L. Collingridge

iScience. 2023 Dec 15; 26(12): 108412. Published online 2023 Nov 7. doi: 10.1016/j.isci.2023.108412

PMCID:: PMC10694656

Abstract Article PDF–3.3M

Select item 104168524.

Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes

Carola Torazza, Francesca Provenzano, Elena Gallia, Maria Cerminara, Matilde Balbi, Tiziana Bonifacino, Sara Tessitore, Silvia Ravera, Cesare Usai, Ilaria Musante, Aldamaria Puliti, Ludo Van Den Bosch, Paymaan Jafar-nejad, Frank Rigo, Marco Milanese, Giambattista Bonanno

Cells. 2023 Aug; 12(15): 1952. Published online 2023 Jul 27. doi: 10.3390/cells12151952

PMCID:: PMC10416852

Abstract Article PDF–5.3M

Select item 103882125.

Striatal mGlu₅-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways

Yuh-Jiin I. Jong, Yukitoshi Izumi, Steven K. Harmon, Charles F. Zorumski, Karen L. ÓMalley

J Biol Chem. 2023 Aug; 299(8): 104949. Published online 2023 Jun 22. doi: 10.1016/j.jbc.2023.104949

PMCID:: PMC10388212

Abstract Article PDF–4.2M

Select item 102671786.

mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior

Xin Li, Zhuo-Jun Du, Jun-Nan Xu, Zhi-Man Liang, Song Lin, Hao Chen, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Gao

Neuropsychopharmacology. 2023 Jul; 48(8): 1164–1174. Published online 2023 Feb 16. doi: 10.1038/s41386-023-01548-w

PMCID:: PMC10267178

Abstract Article PDF–4.1M

Select item 91483107.

mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington’s disease phenotype

Jessica M. de Souza, Talita H. Ferreira-Vieira, Esther M. A. Maciel, Nathalia C. Silva, Izabella B. Quirino Lima, Juliana G. Doria, Isabella G. Olmo, Fabiola M. Ribeiro

Sci Rep. 2022; 12: 8982. Published online 2022 May 28. doi: 10.1038/s41598-022-13029-z

PMCID:: PMC9148310

Abstract Article PDF–5.6M

Select item 89800638.

Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington’s disease

Rebeca P. M. Santos, Roberta Ribeiro, Talita H. Ferreira-Vieira, Rosaria D. Aires, Jessica M. de Souza, Bruna S. Oliveira, Anna Luiza D. Lima, Antônio Carlos P. de Oliveira, Helton J. Reis, Aline S. de Miranda, Erica M. L. Vieira, Fabiola M. Ribeiro, Luciene B. Vieira

Sci Rep. 2022; 12: 5621. Published online 2022 Apr 4. doi: 10.1038/s41598-022-08924-4

PMCID:: PMC8980063

Abstract Article PDF–3.5M

Select item 83460579.

Loss of mGluR5 in D1 Receptor-Expressing Neurons Improves Stress Coping

Luca Zangrandi, Claudia Schmuckermair, Hussein Ghareh, Federico Castaldi, Regine Heilbronn, Gerald Zernig, Francesco Ferraguti, Arnau Ramos-Prats

Int J Mol Sci. 2021 Aug; 22(15): 7826. Published online 2021 Jul 22. doi: 10.3390/ijms22157826

PMCID:: PMC8346057

Abstract Article PDF–2.5M

Select item 823889410.

Genetic disruption of Grm5 causes complex alterations in motor activity, anxiety and social behaviors

Jian Xu, John J. Marshall, Stephen Kraniotis, Toshihiro Nomura, Yongling Zhu, Anis Contractor

Behav Brain Res. Author manuscript; available in PMC 2022 Aug 6.

Published in final edited form as: Behav Brain Res. 2021 Aug 6; 411: 113378. Published online 2021 May 21. doi: 10.1016/j.bbr.2021.113378

PMCID:: PMC8238894

Abstract Article PDF–1.7M

Select item 822832511.

Reduced mGluR5 Activity Modulates Mitochondrial Function

Miguel A. Gonzalez-Lozano, Joke Wortel, Rolinka J. van der Loo, Jan R. T. van Weering, August B. Smit, Ka Wan Li

Cells. 2021 Jun; 10(6): 1375. Published online 2021 Jun 2. doi: 10.3390/cells10061375

PMCID:: PMC8228325

Abstract Article PDF–3.9M

Select item 819901812.

The Density of Group I mGlu₅ Receptors Is Reduced along the Neuronal Surface of Hippocampal Cells in a Mouse Model of Alzheimer’s Disease

Alejandro Martín-Belmonte, Carolina Aguado, Rocío Alfaro-Ruiz, José Luis Albasanz, Mairena Martín, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Luján

Int J Mol Sci. 2021 Jun; 22(11): 5867. Published online 2021 May 30. doi: 10.3390/ijms22115867

PMCID:: PMC8199018

Abstract Article PDF–4.5M

Select item 810621213.

Developmental up-regulation of NMDA receptors in the prefrontal cortex and hippocampus of mGlu5 receptor knock-out mice

Tiziana Imbriglio, Remy Verhaeghe, Nico Antenucci, Stefania Maccari, Giuseppe Battaglia, Ferdinando Nicoletti, Milena Cannella

Mol Brain. 2021; 14: 77. Published online 2021 May 7. doi: 10.1186/s13041-021-00784-9

Correction in:: Mol Brain. 2021; 14: 114.

PMCID:: PMC8106212

Abstract Article PDF–2.0M

Select item 796993314.

BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress

Chelsea R. Kasten, Eleanor B. Holmgren, Mollie R. Lerner, Tiffany A. Wills

Transl Psychiatry. 2021; 11: 178. Published online 2021 Mar 17. doi: 10.1038/s41398-021-01285-y

PMCID:: PMC7969933

Abstract Article PDF–1.2M

Select item 786725115.

ERK-Directed Phosphorylation of mGlu5 Gates Methamphetamine Reward and Reinforcement in Mouse

Elissa K. Fultz, Sema G. Quadir, Douglas Martin, Daniel M. Flaherty, Paul F. Worley, Tod E. Kippin, Karen K. Szumlinski

Int J Mol Sci. 2021 Feb; 22(3): 1473. Published online 2021 Feb 2. doi: 10.3390/ijms22031473

PMCID:: PMC7867251

Abstract Article PDF–2.0M

Select item 765861016.

Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia

Carolina Gubert, Geraldine Kong, Volkan Uzungil, Ariel M. Zeleznikow-Johnston, Emma L. Burrows, Thibault Renoir, Anthony J. Hannan

Front Cell Dev Biol. 2020; 8: 582320. Published online 2020 Oct 29. doi: 10.3389/fcell.2020.582320

PMCID:: PMC7658610

Abstract Article PDF–2.6M

Select item 670571817.

Amplification of mGlu₅-Endocannabinoid Signaling Rescues Behavioral and Synaptic Deficits in a Mouse Model of Adolescent and Adult Dietary Polyunsaturated Fatty Acid Imbalance

Antonia Manduca, Anissa Bara, Thomas Larrieu, Olivier Lassalle, Corinne Joffre, Sophie Layé, Olivier J. Manzoni

J Neurosci. 2017 Jul 19; 37(29): 6851–6868. doi: 10.1523/JNEUROSCI.3516-16.2017

PMCID:: PMC6705718

Abstract Article PDF–4.1M

Select item 660812918.

Mechanisms of Dopamine D1 Receptor-Mediated ERK1/2 Activation in the Parkinsonian Striatum and Their Modulation by Metabotropic Glutamate Receptor Type 5

Tim Fieblinger, Irene Sebastianutto, Cristina Alcacer, Zisis Bimpisidis, Natallia Maslava, Sabina Sandberg, David Engblom, M. Angela Cenci

J Neurosci. 2014 Mar 26; 34(13): 4728–4740. doi: 10.1523/JNEUROSCI.2702-13.2014

PMCID:: PMC6608129

Abstract Article PDF–4.4M

Select item 645884019.

Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses

Jisoo Lim, Eosu Kim, Hyun Jong Noh, Shinwon Kang, Benjamin U. Phillips, Dong Goo Kim, Timothy J. Bussey, Lisa Saksida, Christopher J. Heath, Chul Hoon Kim

Mol Brain. 2019; 12: 37. Published online 2019 Apr 11. doi: 10.1186/s13041-019-0441-8