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Select item 99792151.

Role of a novel mouse mutant of the Galnt2^{tm1Lat/tm1Lat} gene in otitis media

Weijun Ma, Heng Li, Juan Hu, Ying Gao, Hui Lv, Xiaotong Zhang, Qing Zhang, Min Xu, Ying Cheng

Front Neurol. 2022; 13: 1054704. Published online 2023 Feb 16. doi: 10.3389/fneur.2022.1054704

Correction in:: Front Neurol. 2023; 14: 1287032.

PMCID:: PMC9979215

Abstract Article PDF–3.5M

Select item 94408662.

The O-glycosylating enzyme GALNT2 acts as an oncogenic driver in non-small cell lung cancer

Qing Hu, Tian Tian, Yahui Leng, Yuanhui Tang, Shuang Chen, Yueyao Lv, Jingyin Liang, Yanni Liu, Tianhui Liu, Li Shen, Xiaoxia Dong

Cell Mol Biol Lett. 2022; 27: 71. Published online 2022 Sep 4. doi: 10.1186/s11658-022-00378-w

PMCID:: PMC9440866

Abstract Article PDF–5.5M

Select item 90193983.

A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis

Cristy R.C. Verzijl, Federico Oldoni, Natalia Loaiza, Justina C. Wolters, Antoine Rimbert, E. Tian, Weiming Yang, Dicky Struik, Marieke Smit, Niels J. Kloosterhuis, Amy J. Fernandez, Nadine L. Samara, Kelly G. Ten Hagen, Kruti Dalal, Aliona Chernish, Peggy McCluggage, Lawrence A. Tabak, Johan W. Jonker, Jan Albert Kuivenhoven

Mol Metab. 2022 Jun; 60: 101472. Published online 2022 Mar 15. doi: 10.1016/j.molmet.2022.101472

PMCID:: PMC9019398

Abstract Article PDF–3.8M

Select item 75279964.

GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice

Xuedan Li, Yiliang Zhang, Minzhu Zhang, Yan Wang

Sci Rep. 2020; 10: 16168. Published online 2020 Sep 30. doi: 10.1038/s41598-020-73388-3

PMCID:: PMC7527996

Abstract Article PDF–1.8M

Select item 46643665.

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

Christoffer K. Goth, Adnan Halim, Sumeet A. Khetarpal, Daniel J. Rader, Henrik Clausen, Katrine T.-B. G. Schjoldager

Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47): 14623–14628. Published online 2015 Nov 9. doi: 10.1073/pnas.1511175112

PMCID:: PMC4664366

Abstract Article PDF–1.3M

Select item 75341486.

Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function

Monica Zilmer, Andrew C Edmondson, Sumeet A Khetarpal, Viola Alesi, Maha S Zaki, Kevin Rostasy, Camilla G Madsen, Francesca R Lepri, Lorenzo Sinibaldi, Raffaella Cusmai, Antonio Novelli, Mahmoud Y Issa, Christina D Fenger, Rami Abou Jamra, Heiko Reutter, Silvana Briuglia, Emanuele Agolini, Lars Hansen, Ulla E Petäjä-Repo, John Hintze, Kimiyo M Raymond, Kristen Liedtke, Valentina Stanley, Damir Musaev, Joseph G Gleeson, Cecilia Vitali, W Timothy O’Brien, Elena Gardella, Guido Rubboli, Daniel J Rader, Katrine T Schjoldager, Rikke S Møller

Brain. 2020 Apr; 143(4): 1114–1126. Published online 2020 Apr 15. doi: 10.1093/brain/awaa063

PMCID:: PMC7534148

Abstract Article PDF–1.0M

Select item 22260027.

The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele

Jill M. Johnsen, Gallia G. Levy, Randal J. Westrick, Priscilla K. Tucker, David Ginsburg

Mamm Genome. 2008 Jan; 19(1): 32–40. Published online 2008 Jan 11. doi: 10.1007/s00335-007-9079-4

PMCID:: PMC2226002

Abstract Article PDF–502K

Select item 56631928.

Loss of function of GALNT2 lowers high density lipoproteins in humans, nonhuman primates, and rodents

Sumeet A. Khetarpal, Katrine T. Schjoldager, Christina Christoffersen, Avanthi Raghavan, Andrew C. Edmondson, Heiko M. Reutter, Bouhouche Ahmed, R Ouzzani, Gina M. Peloso, Cecilia Vitali, Wei Zhao, Amritha Varshini Hanasoge Somasundara, John S. Millar, YoSon Park, Gayani Fernando, Valentin Livanov, Seungbum Choi, Eric Noé, Pritesh Patel, Siew Peng Ho, Myocardial Infarction Exome Sequencing Study, Todd G. Kirchgessner, Hans H. Wandall, Lars Hansen, Eric P. Bennett, Sergey Y. Vakhrushev, Danish Saleheen, Sekar Kathiresan, Christopher D. Brown, Rami Abou Jamra, Eric LeGuern, Henrik Clausen, Daniel J. Rader

Cell Metab. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Cell Metab. 2016 Aug 9; 24(2): 234–245. doi: 10.1016/j.cmet.2016.07.012

PMCID:: PMC5663192

Abstract Article PDF–2.2M

Select item 41762299.

Overexpression of Galnt3 in Chondrocytes Resulted in Dwarfism Due to the Increase of Mucin-type O-Glycans and Reduction of Glycosaminoglycans

Carolina Andrea Yoshida, Tetsuya Kawane, Takeshi Moriishi, Anurag Purushothaman, Toshihiro Miyazaki, Hisato Komori, Masako Mori, Xin Qin, Ayako Hashimoto, Kazuyuki Sugahara, Kei Yamana, Kenji Takada, Toshihisa Komori

J Biol Chem. 2014 Sep 19; 289(38): 26584–26596. Published online 2014 Aug 8. doi: 10.1074/jbc.M114.555987

PMCID:: PMC4176229

Abstract Article PDF–4.8M

Select item 691120410.

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding

E. Tian, Shengjun Wang, Liping Zhang, Ying Zhang, May C. Malicdan, Yang Mao, Christina Christoffersen, Lawrence A. Tabak, Katrine T. Schjoldager, Kelly G. Ten Hagen

Proc Natl Acad Sci U S A. 2019 Dec 10; 116(50): 25196–25202. Published online 2019 Nov 18. doi: 10.1073/pnas.1909573116

PMCID:: PMC6911204

Abstract Article PDF–1.7M

Select item 699689511.

Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome

Gabriella Peluso, E Tian, Loreto Abusleme, Takashi Munemasa, Taro Mukaibo, Kelly G. Ten Hagen

J Biol Chem. 2020 Jan 31; 295(5): 1411–1425. Published online 2019 Dec 27. doi: 10.1074/jbc.RA119.009807

PMCID:: PMC6996895

Abstract Article PDF–6.5M

Select item 430478912.

Galnt1 Is Required for Normal Heart Valve Development and Cardiac Function

E Tian, Sharon R. Stevens, Yu Guan, Danielle A. Springer, Stasia A. Anderson, Matthew F. Starost, Vyomesh Patel, Kelly G. Ten Hagen, Lawrence A. Tabak

PLoS One. 2015; 10(1): e0115861. Published online 2015 Jan 23. doi: 10.1371/journal.pone.0115861

PMCID:: PMC4304789

Abstract Article PDF–4.1M

Select item 353324713.

O-glycosylation modulates integrin and FGF signaling by influencing the secretion of basement membrane components

E Tian, Matthew P. Hoffman, Kelly G. Ten Hagen

Nat Commun. Author manuscript; available in PMC 2012 Dec 31.

Published in final edited form as: Nat Commun. 2012 May 29; 3: 869. Published online 2012 May 29. doi: 10.1038/ncomms1874

PMCID:: PMC3533247

Abstract Article PDF–6.2M

Select item 629804014.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 18788515.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Abstract Article PDF–287K

Select item 16551116.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Abstract Article PDF–217K

Select item 141356817.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 1683319.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Abstract Article PDF–847K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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