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Select item 109302431.

PGRMC1在多囊卵巢综合征患者中的表达及其调控卵巢颗粒细胞凋亡和糖脂代谢的分子机制

周嘉禾, 陈志静, 李洁明, 邓群娣, 彭秀红, 李荔

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 Apr 28; 48(4): 538–549. Chinese. doi: 10.11817/j.issn.1672-7347.2023.220315

PMCID:: PMC10930243

Abstract Article PDF–2.3M

Select item 108379432.

Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization

Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm

Reprod Biol Endocrinol. 2024; 22: 20. Published online 2024 Feb 3. doi: 10.1186/s12958-024-01188-9

PMCID:: PMC10837943

Abstract Article PDF–2.2M

Select item 106853133.

Progesterone receptor membrane component 1 facilitates Ca²⁺ signal amplification between endosomes and the endoplasmic reticulum

Gihan S. Gunaratne, Sushil Kumar, Yaping Lin-Moshier, James T. Slama, Eugen Brailoiu, Sandip Patel, Timothy F. Walseth, Jonathan S. Marchant

J Biol Chem. 2023 Dec; 299(12): 105378. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105378

PMCID:: PMC10685313

Abstract Article PDF–4.4M

Select item 106049444.

Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma

Claudia Alexandra Dumitru, Hannah Schröder, Frederik Till Alexander Schäfer, Jan Friedrich Aust, Nina Kreße, Carl Ludwig Raven Siebert, Klaus-Peter Stein, Aiden Haghikia, Ludwig Wilkens, Christian Mawrin, Ibrahim Erol Sandalcioglu

Cells. 2023 Oct; 12(20): 2498. Published online 2023 Oct 20. doi: 10.3390/cells12202498

PMCID:: PMC10604944

Abstract Article PDF–2.8M

Select item 92367825.

Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane-Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with Human PGRMC1

Muhammad Tahir Aleem, Asad Khan, Zhaohai Wen, Zhengqing Yu, Kun Li, Aftab Shaukat, Cheng Chen, Tauseef-ur -Rehman, Mingmin Lu, Lixin Xu, Xiaokai Song, Xiangrui Li, Ruofeng Yan

Biomed Res Int. 2022; 2022: 7414198. Published online 2022 Jun 20. doi: 10.1155/2022/7414198

PMCID:: PMC9236782

Abstract Article PDF–1.9M

Select item 87005506.

The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide

Lihua Wang-Eckhardt, Ivonne Becker, Matthias Eckhardt

Cells. 2021 Dec; 10(12): 3520. Published online 2021 Dec 13. doi: 10.3390/cells10123520

PMCID:: PMC8700550

Abstract Article PDF–22M

Select item 85334477.

AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins

Charlotte Thieffry, Marie Van Wynendaele, Asena Aynaci, Mauriane Maja, Caroline Dupuis, Axelle Loriot, Etienne Marbaix, Patrick Henriet

Biomolecules. 2021 Oct; 11(10): 1472. Published online 2021 Oct 6. doi: 10.3390/biom11101472

PMCID:: PMC8533447

Abstract Article PDF–2.7M

Select item 75899598.

PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca²⁺ Entry Via STIM2 in MDA-MB-231 Cells

Carlos Cantonero, Ginés M. Salido, Juan A. Rosado, Pedro C. Redondo

Int J Mol Sci. 2020 Oct; 21(20): 7641. Published online 2020 Oct 15. doi: 10.3390/ijms21207641

PMCID:: PMC7589959

Abstract Article PDF–4.1M

Select item 75539589.

Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling

Diego A. Pedroza, Venkatesh Rajamanickam, Ramadevi Subramani, Alejandra Bencomo, Adriana Galvez, Rajkumar Lakshmanaswamy

Br J Cancer. 2020 Oct 13; 123(8): 1326–1335. Published online 2020 Jul 24. doi: 10.1038/s41416-020-0992-6

PMCID:: PMC7553958

Abstract Article PDF–1.6M

Select item 752031110.

Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis

Hsun‐Yu Huang, Hsiu‐Chuan Chou, Ching‐Hsuan Law, Wan‐Ting Chang, Tzu‐Ning Wen, En‐Chi Liao, Meng‐Wei Lin, Li‐Hsun Lin, Yu‐Shan Wei, Yi‐Ting Tsai, Hsin‐Yi Chen, Kui‐Thong Tan, Wen‐Hung Kuo, Mei‐Lan Ko, Shing‐Jyh Chang, Ying‐Ray Lee, Hong‐Lin Chan

J Cell Mol Med. 2020 Sep; 24(17): 9737–9751. Published online 2020 Jul 16. doi: 10.1111/jcmm.15535

PMCID:: PMC7520311

Abstract Article PDF–1.7M

Select item 735901411.

Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression

Hannah Asperger, Nadia Stamm, Berthold Gierke, Michael Pawlak, Ute Hofmann, Ulrich M. Zanger, Annamaria Marton, Robert L. Katona, Andrea Buhala, Csaba Vizler, Jan-Philipp Cieslik, Eugen Ruckhäberle, Dieter Niederacher, Tanja Fehm, Hans Neubauer, Marina Ludescher

Breast Cancer Res. 2020; 22: 75. Published online 2020 Jul 13. doi: 10.1186/s13058-020-01312-8

Correction in:: Breast Cancer Res. 2021; 23: 13.

PMCID:: PMC7359014

Abstract Article PDF–2.2M

Select item 716096412.

PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease

Bashar M. Thejer, Partho P. Adhikary, Sarah L. Teakel, Johnny Fang, Paul A. Weston, Saliya Gurusinghe, Ayad G. Anwer, Martin Gosnell, Jalal A. Jazayeri, Marina Ludescher, Lesley-Ann Gray, Michael Pawlak, Robyn H. Wallace, Sameer D. Pant, Marie Wong, Tamas Fischer, Elizabeth J. New, Tanja N. Fehm, Hans Neubauer, Ewa M. Goldys, Jane C. Quinn, Leslie A. Weston, Michael A. Cahill

BMC Mol Cell Biol. 2020; 21: 26. Published online 2020 Apr 15. doi: 10.1186/s12860-020-00268-z

PMCID:: PMC7160964

Abstract Article PDF–1.9M

Select item 707603813.

Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells

Ying Lin, Kazuma Higashisaka, Takuya Shintani, Ayaka Maki, Sachiyo Hanamuro, Yuya Haga, Shinichiro Maeda, Hirofumi Tsujino, Kazuya Nagano, Yasushi Fujio, Yasuo Tsutsumi

Sci Rep. 2020; 10: 4748. Published online 2020 Mar 16. doi: 10.1038/s41598-020-61727-3

PMCID:: PMC7076038

Abstract Article PDF–1.6M

Select item 585013414.

Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma

Hung-Wen Tsai, Chung-Liang Ho, Shu-Wen Cheng, Yih-Jyh Lin, Chou-Cheng Chen, Pin-Nan Cheng, Chia-Jui Yen, Ting-Tsung Chang, Po-Min Chiang, Shih-Huang Chan, Cheng-Hsun Ho, Shu-Hui Chen, Yi-Wen Wang, Nan-Haw Chow, Jou-Chun Lin

World J Gastroenterol. 2018 Mar 14; 24(10): 1152–1166. Published online 2018 Mar 14. doi: 10.3748/wjg.v24.i10.1152

PMCID:: PMC5850134

Abstract Article PDF–1.7M

Select item 524910015.

PGRMC1 Is a Novel Potential Tumor Biomarker of Human Renal Cell Carcinoma Based on Quantitative Proteomic and Integrative Biological Assessments

Dan Zhang, Xiangying Xia, Xixi Wang, Peng Zhang, Weiliang Lu, Yamei Yu, Shi Deng, Hanshuo Yang, Hongxia Zhu, Ningzhi Xu, Shufang Liang

PLoS One. 2017; 12(1): e0170453. Published online 2017 Jan 20. doi: 10.1371/journal.pone.0170453

PMCID:: PMC5249100

Abstract Article PDF–1.7M

Select item 474030316.

The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes

Uyen B. Chu, Timur A. Mavlyutov, Ming-Liang Chu, Huan Yang, Amanda Schulman, Christophe Mesangeau, Christopher R. McCurdy, Lian-Wang Guo, Arnold E. Ruoho

EBioMedicine. 2015 Nov; 2(11): 1806–1813. Published online 2015 Oct 19. doi: 10.1016/j.ebiom.2015.10.017