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Select item 92265321.

Phosphorylation-dependent association of human chromatin protein PC4 to linker histone H1 regulates genome organization and transcription

Pallabi Mustafi, Mingli Hu, Sujata Kumari, Chandrima Das, Guohong Li, Tapas K Kundu

Nucleic Acids Res. 2022 Jun 24; 50(11): 6116–6136. Published online 2022 Jun 7. doi: 10.1093/nar/gkac450

PMCID:: PMC9226532

Abstract Article PDF–5.4M

Select item 64690382.

Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect

Peng Luo, Chi Zhang, Fengying Liao, Long Chen, Zhenyu Liu, Lei Long, Zhongyong Jiang, Yawei Wang, Ziwen Wang, Zujuan Liu, Hongming Miao, Chunmeng Shi

Cell Commun Signal. 2019; 17: 36. Published online 2019 Apr 16. doi: 10.1186/s12964-019-0348-0

PMCID:: PMC6469038

Abstract Article PDF–11M

Select item 60629813.

Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression

Aleksandra Brzek, Marlena Cichocka, Jakub Dolata, Wojciech Juzwa, Daniel Schümperli, Katarzyna Dorota Raczynska

BMC Mol Biol. 2018; 19: 9. Published online 2018 Jul 27. doi: 10.1186/s12867-018-0110-y

PMCID:: PMC6062981

Abstract Article PDF–1.5M

Select item 57918124.

Sub1 and RNAPII, until termination does them part

Olga Calvo

Transcription. 2018; 9(1): 52–60. Published online 2017 Aug 30. doi: 10.1080/21541264.2017.1333558

PMCID:: PMC5791812

Abstract Article PDF–654K

Select item 54654835.

A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4

Wezley C. Griffin, Jun Gao, Alicia K. Byrd, Shubeena Chib, Kevin D. Raney

J Biol Chem. 2017 Jun 9; 292(23): 9567–9582. Published online 2017 Apr 17. doi: 10.1074/jbc.M117.776211

PMCID:: PMC5465483

Abstract Article PDF–3.5M

Select item 51407776.

MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer

B V S K Chakravarthi, M T Goswami, S S Pathi, A D Robinson, M Cieślik, D S Chandrashekar, S Agarwal, J Siddiqui, S Daignault, S L Carskadon, X Jing, A M Chinnaiyan, L P Kunju, N Palanisamy, S Varambally

Oncogene. 2016 Dec 8; 35(49): 6330–6340. Published online 2016 Jun 6. doi: 10.1038/onc.2016.164

PMCID:: PMC5140777

Abstract Article PDF–1.2M

Select item 3505667.

General Transcriptional Coactivator PC4 Activates p53 Function

Sourav Banerjee, B. R. Prashanth Kumar, Tapas K. Kundu

Mol Cell Biol. 2004 Mar; 24(5): 2052–2062. doi: 10.1128/MCB.24.5.2052-2062.2004

PMCID:: PMC350566

Abstract Article PDF–817K

Select item 1038308.

The Adeno-Associated Virus Type 2 Regulatory Proteins Rep78 and Rep68 Interact with the Transcriptional Coactivator PC4

Stefan Weger, Meike Wendland, Jürgen A. Kleinschmidt, Regine Heilbronn

J Virol. 1999 Jan; 73(1): 260–269. doi: 10.1128/jvi.73.1.260-269.1999

PMCID:: PMC103830

Abstract Article PDF–781K

Select item 108641109.

Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle

Qimei Pan, Peng Luo, Kaishun Hu, Yuntan Qiu, Gaoyu Liu, Shijie Dai, Bokang Cui, Dong Yin, Chunmeng Shi

J Cell Biol. 2024 Mar 4; 223(3): e202308066. Published online 2024 Feb 13. doi: 10.1083/jcb.202308066

PMCID:: PMC10864110

Abstract Article PDF–8.9M

Select item 591159410.

Inhibition of PC4 radiosensitizes non‐small cell lung cancer by transcriptionally suppressing XLF

Tian Zhang, Xiaojie Liu, Xiuli Chen, Jing Wang, Yuwen Wang, Dong Qian, Qingsong Pang, Ping Wang

Cancer Med. 2018 Apr; 7(4): 1326–1337. Published online 2018 Mar 9. doi: 10.1002/cam4.1332

PMCID:: PMC5911594

Abstract Article PDF–1.1M

Select item 464952011.

Inhibition of human positive cofactor 4 radiosensitizes human esophageal squmaous cell carcinoma cells by suppressing XLF-mediated nonhomologous end joining

D Qian, B Zhang, X-L Zeng, J M Le Blanc, Y-H Guo, C Xue, C Jiang, H-H Wang, T-S Zhao, M-B Meng, L-J Zhao, J-H Hao, P Wang, D Xie, B Lu, Z-Y Yuan

Cell Death Dis. 2014 Oct; 5(10): e1461. Published online 2014 Oct 16. doi: 10.1038/cddis.2014.416

PMCID:: PMC4649520

Abstract Article PDF–3.7M

Select item 460531812.

Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells

Jin-Man Kim, Kyunghwan Kim, Thomas Schmidt, Vasu Punj, Haley Tucker, Judd C. Rice, Tobias S. Ulmer, Woojin An

Nucleic Acids Res. 2015 Oct 15; 43(18): 8868–8883. Published online 2015 Oct 10. doi: 10.1093/nar/gkv874

PMCID:: PMC4605318

Abstract Article PDF–7.1M

Select item 446534913.

Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA

Jun Gao, Boris L. Zybailov, Alicia K. Byrd, Wezley C. Griffin, Shubeena Chib, Samuel G. Mackintosh, Alan J. Tackett, Kevin D. Raney

Chem Commun (Camb) Author manuscript; available in PMC 2016 Apr 28.

Published in final edited form as: Chem Commun (Camb). 2015 Apr 28; 51(33): 7242–7244. doi: 10.1039/c5cc00742a

PMCID:: PMC4465349

Abstract Article PDF–1.0M

Select item 313708114.

Peptide-Protein Interactions Suggest That Acetylation of Lysines 381 and 382 of p53 Is Important for Positive Coactivator 4-p53 Interaction

Subrata Debnath, Snehajyoti Chatterjee, Mohammed Arif, Tapas K. Kundu, Siddhartha Roy

J Biol Chem. 2011 Jul 15; 286(28): 25076–25087. Published online 2011 May 17. doi: 10.1074/jbc.M110.205328

PMCID:: PMC3137081

Abstract Article PDF–3.1M

Select item 278203815.

Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin

Kodihalli C. Ravindra, B. Ruthrotha Selvi, Mohammed Arif, B. A. Ashok Reddy, Gali R. Thanuja, Shipra Agrawal, Suman Kalyan Pradhan, Natesh Nagashayana, Dipak Dasgupta, Tapas K. Kundu

J Biol Chem. 2009 Sep 4; 284(36): 24453–24464. Published online 2009 Jul 1. doi: 10.1074/jbc.M109.023861

PMCID:: PMC2782038

Abstract Article PDF–2.4M

Select item 275589516.

Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

Sridharan Rajagopalan, Antonina Andreeva, Daniel P. Teufel, Stefan M. Freund, Alan R. Fersht

J Biol Chem. 2009 Aug 7; 284(32): 21728–21737. Published online 2009 Jun 12. doi: 10.1074/jbc.M109.006429

PMCID:: PMC2755895

Abstract Article PDF–2.4M

Select item 259282417.

Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites

Oliver Mortusewicz, Wera Roth, Na Li, M. Cristina Cardoso, Michael Meisterernst, Heinrich Leonhardt

J Cell Biol. 2008 Dec 1; 183(5): 769–776. doi: 10.1083/jcb.200808097

PMCID:: PMC2592824

Abstract Article PDF–2.0M

Select item 216906918.

Activation of p53 Function by Human Transcriptional Coactivator PC4: Role of Protein-Protein Interaction, DNA Bending, and Posttranslational Modifications

Kiran Batta, Tapas K. Kundu

Mol Cell Biol. 2007 Nov; 27(21): 7603–7614. Published online 2007 Sep 4. doi: 10.1128/MCB.01064-07

Correction in:: Mol Cell Biol. 2020 Oct; 40(19): e00364-20.

PMCID:: PMC2169069

Abstract Article PDF–686K

Select item 163676919.

Transcriptional Coactivator PC4, a Chromatin-Associated Protein, Induces Chromatin Condensation

Chandrima Das, Kohji Hizume, Kiran Batta, B. R. Prashanth Kumar, Shrikanth S. Gadad, Semanti Ganguly, Stephanie Lorain, Alain Verreault, Parag P. Sadhale, Kunio Takeyasu, Tapas K. Kundu

Mol Cell Biol. 2006 Nov; 26(22): 8303–8315. Published online 2006 Sep 18. doi: 10.1128/MCB.00887-06