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Select item 88385901.

Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1

Miriam R. B. Porzberg, Laust Moesgaard, Catrine Johansson, Udo Oppermann, Jacob Kongsted, Jasmin Mecinović

Molecules. 2022 Feb; 27(3): 983. Published online 2022 Feb 1. doi: 10.3390/molecules27030983

PMCID:: PMC8838590

Abstract Article PDF–2.0M

Select item 81992162.

Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors

Chiara Luise, Dina Robaa, Pierre Regenass, David Maurer, Dmytro Ostrovskyi, Ludwig Seifert, Johannes Bacher, Teresa Burgahn, Tobias Wagner, Johannes Seitz, Holger Greschik, Kwang-Su Park, Yan Xiong, Jian Jin, Roland Schüle, Bernhard Breit, Manfred Jung, Wolfgang Sippl

Int J Mol Sci. 2021 Jun; 22(11): 5910. Published online 2021 May 31. doi: 10.3390/ijms22115910

PMCID:: PMC8199216

Abstract Article PDF–8.3M

Select item 44671143.

The histone code reader SPIN1 controls RET signaling in liposarcoma

Henriette Franz, Holger Greschik, Dominica Willmann, Luka Ozretić, Cordula Annette Jilg, Eva Wardelmann, Manfred Jung, Reinhard Buettner, Roland Schüle

Oncotarget. 2015 Mar 10; 6(7): 4773–4789. Published online 2015 Mar 5. doi: 10.18632/oncotarget.3000

PMCID:: PMC4467114

Abstract Article PDF–6.7M

Select item 88100244.

The microRNA-381(miR-381)/Spindlin1(SPIN1) axis contributes to cell proliferation and invasion of colorectal cancer cells by regulating the Wnt/β-catenin pathway

Ling Zhou, Heng Wang, Zhi Fang, Min Zhong, Yan He, Jianping Zou, Shanshan Huang, Junhe Li, Xiaojun Xiang, Ziling Fang

Bioengineered. 2021; 12(2): 12036–12048. Published online 2021 Dec 27. doi: 10.1080/21655979.2021.2003663

PMCID:: PMC8810024

Abstract Article PDF–3.3M

Select item 75307875.

E2F1‐activated SPIN1 promotes tumor growth via a MDM2‐p21‐E2F1 feedback loop in gastric cancer

Bei‐bei Lv, Ran‐ran Ma, Xu Chen, Guo‐hao Zhang, Lin Song, Su‐xia Wang, Ya‐wen Wang, Hai‐ting Liu, Peng Gao

Mol Oncol. 2020 Oct; 14(10): 2629–2645. Published online 2020 Aug 26. doi: 10.1002/1878-0261.12778

PMCID:: PMC7530787

Abstract Article PDF–15M

Select item 54387046.

Suppressive role exerted by microRNA-29b-1-5p in triple negative breast cancer through SPIN1 regulation

Rosa Drago-Ferrante, Francesca Pentimalli, Daniela Carlisi, Anna De Blasio, Christian Saliba, Shawn Baldacchino, James Degaetano, Joseph Debono, Gordon Caruana-Dingli, Godfrey Grech, Christian Scerri, Giovanni Tesoriere, Antonio Giordano, Renza Vento, Riccardo Di Fiore

Oncotarget. 2017 Apr 25; 8(17): 28939–28958. Published online 2017 Mar 7. doi: 10.18632/oncotarget.15960

PMCID:: PMC5438704

Abstract Article PDF–6.3M

Select item 34977617.

Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1

Na Yang, Weixiang Wang, Yan Wang, Mingzhu Wang, Qiang Zhao, Zihe Rao, Bing Zhu, Rui-Ming Xu

Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44): 17954–17959. Published online 2012 Oct 17. doi: 10.1073/pnas.1208517109

PMCID:: PMC3497761

Abstract Article PDF–1.0M

Select item 74484658.

Long noncoding RNA PSMA3-AS1 functions as a microRNA-409-3p sponge to promote the progression of non-small cell lung carcinoma by targeting spindlin 1

Lingling Wang, Lei Wu, Jinfeng Pang

Oncol Rep. 2020 Oct; 44(4): 1550–1560. Published online 2020 Jul 15. doi: 10.3892/or.2020.7693

PMCID:: PMC7448465

Abstract Article PDF–2.1M

Select item 32071049.

Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes

Weixiang Wang, Zhi Chen, Zhuo Mao, Huihui Zhang, Xiaojun Ding, She Chen, Xiaodong Zhang, Ruiming Xu, Bing Zhu

EMBO Rep. 2011 Nov; 12(11): 1160–1166. Published online 2011 Sep 30. doi: 10.1038/embor.2011.184

PMCID:: PMC3207104

Abstract Article PDF–940K

Select item 396705010.

Molecular basis underlying histone H3 lysine–arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1

Xiaonan Su, Guixin Zhu, Xiaozhe Ding, Shirley Y. Lee, Yali Dou, Bing Zhu, Wei Wu, Haitao Li

Genes Dev. 2014 Mar 15; 28(6): 622–636. doi: 10.1101/gad.233239.113

PMCID:: PMC3967050

Abstract Article PDF–1.9M

Select item 587133411.

SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer

Ziling Fang, Bo Cao, Jun-Ming Liao, Jun Deng, Kevin D Plummer, Peng Liao, Tao Liu, Wensheng Zhang, Kun Zhang, Li Li, David Margolin, Shelya X Zeng, Jianping Xiong, Hua Lu

eLife. 2018; 7: e31275. Published online 2018 Mar 16. doi: 10.7554/eLife.31275

PMCID:: PMC5871334

Abstract Article PDF–2.8M

Select item 574305912.

A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1

Narkhyun Bae, Min Gao, Xu Li, Tolkappiyan Premkumar, Gianluca Sbardella, Junjie Chen, Mark T. Bedford

J Biol Chem. 2017 Dec 22; 292(51): 20808–20817. Published online 2017 Oct 23. doi: 10.1074/jbc.M117.814913

PMCID:: PMC5743059

Abstract Article PDF–2.1M

Select item 577540013.

The histone code reader Spin1 controls skeletal muscle development

Holger Greschik, Delphine Duteil, Nadia Messaddeq, Dominica Willmann, Laura Arrigoni, Manuela Sum, Manfred Jung, Daniel Metzger, Thomas Manke, Thomas Günther, Roland Schüle

Cell Death Dis. 2017 Nov; 8(11): e3173. Published online 2017 Nov 23. doi: 10.1038/cddis.2017.468

PMCID:: PMC5775400

Abstract Article PDF–6.2M

Select item 296775014.

An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Nicholas P Tatonetti, Joel T Dudley, Hersh Sagreiya, Atul J Butte, Russ B Altman

BMC Bioinformatics. 2010; 11(Suppl 9): S9. Published online 2010 Oct 28. doi: 10.1186/1471-2105-11-S9-S9

PMCID:: PMC2967750

Abstract Article PDF–368K

Select item 364025315.

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

Till Bartke, Michiel Vermeulen, Blerta Xhemalce, Samuel C. Robson, Matthias Mann, Tony Kouzarides

Cell. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Cell. 2010 Oct 29; 143(3): 470–484. doi: 10.1016/j.cell.2010.10.012

PMCID:: PMC3640253

Abstract Article PDF–3.9M

Select item 577591416.

A chemical proteomics approach to reveal direct protein-protein interactions in living cells

Ralph E. Kleiner, Lisa E. Hang, Kelly R. Molloy, Brian T. Chait, Tarun M. Kapoor

Cell Chem Biol. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Cell Chem Biol. 2018 Jan 18; 25(1): 110–120.e3. Published online 2017 Nov 5. doi: 10.1016/j.chembiol.2017.10.001

PMCID:: PMC5775914

Abstract Article PDF–2.1M

Select item 772476017.

Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Jonathan P. Davies, Katherine M. Almasy, Eli F. McDonald, Lars Plate

ACS Infect Dis. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: ACS Infect Dis. 2020 Dec 11; 6(12): 3174–3189. Published online 2020 Dec 2. doi: 10.1021/acsinfecdis.0c00500

PMCID:: PMC7724760

Abstract Article PDF–2.1M

Select item 689579318.

Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications

Aida Barreiro-Alonso, María Cámara-Quílez, Martín Salamini-Montemurri, Mónica Lamas-Maceiras, Ángel Vizoso-Vázquez, Esther Rodríguez-Belmonte, María Quindós-Varela, Olaia Martínez-Iglesias, Angélica Figueroa, María-Esperanza Cerdán

Cancers (Basel) 2019 Nov; 11(11): 1729. Published online 2019 Nov 5. doi: 10.3390/cancers11111729

PMCID:: PMC6895793

Abstract Article PDF–3.1M

Select item 544566019.

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras

Tim Wang, Haiyan Yu, Nicholas W. Hughes, Bingxu Liu, Arek Kendirli, Klara Klein, Walter W. Chen, Eric S. Lander, David M. Sabatini

Cell. Author manuscript; available in PMC 2018 Feb 23.

Published in final edited form as: Cell. 2017 Feb 23; 168(5): 890–903.e15. Published online 2017 Feb 2. doi: 10.1016/j.cell.2017.01.013

PMCID:: PMC5445660

Abstract Article PDF–2.2M

Select item 863966820.

TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease

Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko

Neuron. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031

PMCID:: PMC8639668

Abstract Article PDF–2.6M

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