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Select item 97314931.

Alzheimer’s risk factor FERMT2 promotes the progression of colorectal carcinoma via Wnt/β-catenin signaling pathway and contributes to the negative correlation between Alzheimer and cancer

Wenzhen Xia, Zhaoyu Gao, Xia Jiang, Lei Jiang, Yushi Qin, Di Zhang, Pei Tian, Wanchang Wang, Qi Zhang, Rui Zhang, Nan Zhang, Shunjiang Xu

PLoS One. 2022; 17(12): e0278774. Published online 2022 Dec 8. doi: 10.1371/journal.pone.0278774

PMCID:: PMC9731493

Abstract Article PDF–3.4M

Select item 90181822.

Kindlin-2 Promotes Chondrogenesis and Ameliorates IL-1beta-Induced Inflammation in Chondrocytes Cocultured with BMSCs in the Direct Contact Coculture System

Zhefeng Chen, Kai Shen, Ziyang Zheng, Jinchun Zhou, Shujie Zhao, Huanghe Song, Jiuxiang Liu, Xuan Zhao, Feng Liu, Qiang Zuo

Oxid Med Cell Longev. 2022; 2022: 3156245. Published online 2022 Apr 12. doi: 10.1155/2022/3156245

PMCID:: PMC9018182

Abstract Article PDF–3.3M

Select item 87584963.

Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

Fanny Eysert, Audrey Coulon, Emmanuelle Boscher, Anaїs-Camille Vreulx, Amandine Flaig, Tiago Mendes, Sandrine Hughes, Benjamin Grenier-Boley, Xavier Hanoulle, Florie Demiautte, Charlotte Bauer, Mikael Marttinen, Mari Takalo, Philippe Amouyel, Shruti Desai, Ian Pike, Mikko Hiltunen, Frédéric Chécler, Mélissa Farinelli, Charlotte Delay, Nicolas Malmanche, Sébastien S. Hébert, Julie Dumont, Devrim Kilinc, Jean-Charles Lambert, Julien Chapuis

Mol Psychiatry. 2021; 26(10): 5592–5607. Published online 2020 Nov 3. doi: 10.1038/s41380-020-00926-w

Correction in:: Mol Psychiatry. 2021; 26(10): 5608.

PMCID:: PMC8758496

Abstract Article PDF–4.0M

Select item 77669484.

Kindlin-2 Mediates Mechanical Activation of Cardiac Myofibroblasts

Elena Godbout, Dong Ok Son, Stephanie Hume, Stellar Boo, Vincent Sarrazy, Sophie Clément, Andras Kapus, Bernhard Wehrle-Haller, Leena Bruckner-Tuderman, Cristina Has, Boris Hinz

Cells. 2020 Dec; 9(12): 2702. Published online 2020 Dec 17. doi: 10.3390/cells9122702

PMCID:: PMC7766948

Abstract Article PDF–3.7M

Select item 72517775.

Kindlin-2 suppresses cervical cancer cell migration through AKT/mTOR-mediated autophagy induction

Guangteng Wu, Ying Long, Yan Lu, Yiming Feng, Xinmei Yang, Xun Xu, Desheng Yao

Oncol Rep. 2020 Jul; 44(1): 69–76. Published online 2020 May 4. doi: 10.3892/or.2020.7603

PMCID:: PMC7251777

Abstract Article PDF–901K

Select item 62116066.

Fermitin family homolog-2 (FERMT2) is highly expressed in human placental villi and modulates trophoblast invasion

Eiko Kawamura, Gina B. Hamilton, Ewa I. Miskiewicz, Daniel J. MacPhee

BMC Dev Biol. 2018; 18: 19. Published online 2018 Nov 1. doi: 10.1186/s12861-018-0178-0

PMCID:: PMC6211606

Abstract Article PDF–10M

Select item 56239737.

Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/β-catenin signaling

Jie Lin, Wansong Lin, Yunbin Ye, Liping Wang, Xiaoyan Chen, Shengbing Zang, Aimin Huang

J Exp Clin Cancer Res. 2017; 36: 134. Published online 2017 Sep 29. doi: 10.1186/s13046-017-0603-4

PMCID:: PMC5623973

Abstract Article PDF–4.8M

Select item 55337288.

Kindlin-2 could influence breast nodule elasticity and improve lymph node metastasis in invasive breast cancer

Xiaowei Xue, Junlai Li, Wenbo Wan, Xianquan Shi, Yiqiong Zheng

Sci Rep. 2017; 7: 6753. Published online 2017 Jul 28. doi: 10.1038/s41598-017-07075-1

PMCID:: PMC5533728

Abstract Article PDF–5.3M

Select item 51299129.

FERMT2 rs17125944 polymorphism with Alzheimer's disease risk: a replication and meta-analysis

Qiu-Yue Zhang, Hui-Fu Wang, Zhan-Jie Zheng, Ling-Li Kong, Meng-Shan Tan, Chen-Chen Tan, Wei Zhang, Zi-Xuan Wang, Lin Tan, Jin-Tai Yu, Lan Tan

Oncotarget. 2016 Jun 28; 7(26): 39044–39050. Published online 2016 May 27. doi: 10.18632/oncotarget.9679

PMCID:: PMC5129912

Abstract Article PDF–1.1M

Select item 431524310.

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network

Vira V. Artym, Stephen Swatkoski, Kazue Matsumoto, Catherine B. Campbell, Ryan J. Petrie, Emilios K. Dimitriadis, Xin Li, Susette C. Mueller, Thomas H. Bugge, Marjan Gucek, Kenneth M. Yamada

J Cell Biol. 2015 Feb 2; 208(3): 331–350. doi: 10.1083/jcb.201405099

PMCID:: PMC4315243

Abstract Article PDF–5.3M

Select item 310714611.

Crystallization and preliminary X-ray crystallographic analysis of the human kindlin-2 PH domain

Jun Hyuck Lee, Jun Yop An, HaJeung Park, Hak Jun Kim, Soo Hyun Eom

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1; 67(Pt 6): 696–699. Published online 2011 May 26. doi: 10.1107/S1744309111013820

PMCID:: PMC3107146

Abstract Article PDF–585K

Select item 310525312.

Kindlin-2 Expression in Arsenite and Cadmium Transformed Bladder Cancer Cell Lines and in Archival Specimens of Human Bladder Cancer

Sherine Talaat, Seema Somji, Conrad Toni, Scott H. Garrett, Xu Dong Zhou, Mary Ann Sens, Donald A. Sens

Urology. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Urology. 2011 Jun; 77(6): 1507.e1–1507.e7. doi: 10.1016/j.urology.2011.02.040

PMCID:: PMC3105253

Abstract Article PDF–510K

Select item 1107228613.

Kindlin-2 controls angiogenesis through modulating Notch1 signaling

Yuechao Dong, Guixing Ma, Xiaoting Hou, Yingying Han, Zhen Ding, Wanze Tang, Litong Chen, Yangshan Chen, Bo Zhou, Feng Rao, Kaosheng Lv, Changzheng Du, Huiling Cao

Cell Mol Life Sci. 2023 Aug; 80(8): 223. Published online 2023 Jul 22. doi: 10.1007/s00018-023-04866-w

PMCID:: PMC11072286

Abstract Article PDF–5.5M

Select item 1023645614.

Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression

Minjeong Yeon, Irene Bertolini, Ekta Agarwal, Jagadish C. Ghosh, Hsin-Yao Tang, David W. Speicher, Frederick Keeney, Khalid Sossey-Alaoui, Elzbieta Pluskota, Katarzyna Bialkowska, Edward F. Plow, Lucia R. Languino, Emmanuel Skordalakes, M. Cecilia Caino, Dario C. Altieri

J Biol Chem. 2023 Jun; 299(6): 104774. Published online 2023 May 2. doi: 10.1016/j.jbc.2023.104774

PMCID:: PMC10236456

Abstract Article PDF–3.1M

Select item 912295115.

Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression

Luyao Ma, Yeteng Tian, Tao Qian, Wenjun Li, Chengmin Liu, Bizhu Chu, Qian Kong, Renwei Cai, Panzhu Bai, Lisha Ma, Yi Deng, Ruijun Tian, Chuanyue Wu, Ying Sun

Cell Death Dis. 2022 May; 13(5): 482. Published online 2022 May 20. doi: 10.1038/s41419-022-04945-z

PMCID:: PMC9122951

Abstract Article PDF–6.2M

Select item 879452816.

YBX1 knockdown induces renal cell carcinoma cell apoptosis via Kindlin-2

Qiqi Cui, Chao Wang, Shuang Liu, Runxuan Du, Shaoping Tian, Ruibing Chen, Hua Geng, Saravanan Subramanian, Yuanjie Niu, Yong Wang, Dan Yue

Cell Cycle. 2021; 20(22): 2413–2427. Published online 2021 Oct 28. doi: 10.1080/15384101.2021.1985771

PMCID:: PMC8794528

Abstract Article PDF–7.6M

Select item 783951617.

miRNA‐200c‐3p promotes endothelial to mesenchymal transition and neointimal hyperplasia in artery bypass grafts

Dan Chen, Cheng Zhang, Jiangyong Chen, Mei Yang, Tayyab A Afzal, Weiwei An, Eithne M Maguire, Shiping He, Jun Luo, Xiaowen Wang, Yu Zhao, Qingchen Wu, Qingzhong Xiao

J Pathol. 2021 Feb; 253(2): 209–224. Published online 2020 Nov 28. doi: 10.1002/path.5574

PMCID:: PMC7839516

Abstract Article PDF–25M

Select item 736762118.

HIF‐1α interacts with Kindlin‐2 and influences breast cancer elasticity: A study based on shear wave elastography imaging

Xiaowei Xue, Shaowei Xue, Wenbo Wan, Junlai Li, Huaiyin Shi

Cancer Med. 2020 Jul; 9(14): 4971–4979. Published online 2020 May 21. doi: 10.1002/cam4.3130

PMCID:: PMC7367621

Abstract Article PDF–1.1M

Select item 719664719.

The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining α-tubulin acetylation

Hui-Foon Tan, Suet-Mien Tan

J Biol Chem. 2020 May 1; 295(18): 5928–5943. Published online 2020 Mar 13. doi: 10.1074/jbc.RA120.012954

PMCID:: PMC7196647

Abstract Article PDF–3.9M

Select item 627572720.

Functional characterization of human Kindlin-2 core promoter identifies a key role of SP1 in Kindlin-2 transcriptional regulation

Ammad Aslam Khan, Takashi Shimokawa, Staffan Strömblad, Hongquan Zhang

Cell Mol Biol Lett. 2011 Dec; 16(4): 638. Published online 2011 Sep 15. doi: 10.2478/s11658-011-0028-6

PMCID:: PMC6275727

Summary PDF–934K

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