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Items: 1 to 20 of 38

1.
ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin Signaling
Cong Xu, Yi-Ming Li, Bo Sun, Fang-Jing Zhong, Lian-Yue Yang
Mol Cancer Res. 2021 Sep 1; 19(9): 1441–1453. Published online 2021 Jun 22. doi: 10.1158/1541-7786.MCR-21-0027
PMCID:
PMC9398136
AbstractArticlePDF–2.3M
2.
Multiple competing RNA structures dynamically control alternative splicing in the human ATE1 gene
Marina Kalinina, Dmitry Skvortsov, Svetlana Kalmykova, Timofei Ivanov, Olga Dontsova, Dmitri D Pervouchine
Nucleic Acids Res. 2021 Jan 11; 49(1): 479–490. Published online 2020 Dec 16. doi: 10.1093/nar/gkaa1208
PMCID:
PMC7797038
AbstractArticlePDF–1.5M
3.
Arginyl-tRNA-protein transferase 1 contributes to governing optimal stability of the human immunodeficiency virus type 1 core
Naoki Kishimoto, Ryosuke Okano, Ayano Akita, Satoshi Miura, Ayaka Irie, Nobutoki Takamune, Shogo Misumi
Retrovirology. 2021; 18: 30. Published online 2021 Sep 26. doi: 10.1186/s12977-021-00574-0
PMCID:
PMC8474785
AbstractArticlePDF–1.3M
4.
Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis
Michael D. Birnbaum, Ning Zhao, Balaji T. Moorthy, Devang M. Patel, Oleksandr N. Kryvenko, Laine Heidman, Akhilesh Kumar, William M. Morgan, Yuguang Ban, Isildinha M. Reis, Xi Chen, Mark L. Gonzalgo, Merce Jorda, Kerry L. Burnstein, Fangliang Zhang
Oncogene. Author manuscript; available in PMC 2019 Mar 3.
Published in final edited form as: Oncogene. 2019 Feb; 38(6): 838–851. Published online 2018 Sep 3. doi: 10.1038/s41388-018-0462-2
PMCID:
PMC6368462
AbstractArticlePDF–1.0M
5.
Arginyltransferase ATE1 suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers
Reena Rai, Fangliang Zhang, Kristen Colavita, Nicolae Adrian Leu, Satoshi Kurosaka, Akhilesh Kumar, Michael D. Birnbaum, Balázs Gyorffy, Dawei W. Dong, Michael Shtutman, Anna Kashina
Oncogene. Author manuscript; available in PMC 2016 Aug 10.
Published in final edited form as: Oncogene. 2016 Aug 4; 35(31): 4058–4068. Published online 2015 Dec 21. doi: 10.1038/onc.2015.473
PMCID:
PMC4916053
AbstractArticlePDF–2.4M
6.
Inhibition of Arginyltransferase 1 Induces Transcriptional Activity of Myocardin-related Transcription Factor A (MRTF-A) and Promotes Directional Migration
Patricia A. Eisenach, Franziska Schikora, Guido Posern
J Biol Chem. 2014 Dec 19; 289(51): 35376–35387. Published online 2014 Nov 7. doi: 10.1074/jbc.M114.578674
PMCID:
PMC4271223
AbstractArticlePDF–4.0M
7.
Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis
Sougata Saha, Junling Wang, Brian Buckley, Qingqing Wang, Brenda Lilly, Mikhail Chernov, Anna Kashina
Biochem Pharmacol. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Biochem Pharmacol. 2012 Apr 1; 83(7): 866–873. Published online 2012 Jan 18. doi: 10.1016/j.bcp.2012.01.012
PMCID:
PMC3288401
AbstractArticlePDF–1.9M
8.
Arginylation-dependent regulation of a proteolytic product of talin is essential for cell–cell adhesion
Fangliang Zhang, Sougata Saha, Anna Kashina
J Cell Biol. 2012 Jun 11; 197(6): 819–836. doi: 10.1083/jcb.201112129
PMCID:
PMC3373405
AbstractArticlePDF–4.6M
9.
The C-terminal Proteolytic Fragment of the Breast Cancer Susceptibility Type 1 Protein (BRCA1) Is Degraded by the N-end Rule Pathway
Zhizhong Xu, Roshani Payoe, Richard P. Fahlman
J Biol Chem. 2012 Mar 2; 287(10): 7495–7502. Published online 2012 Jan 18. doi: 10.1074/jbc.M111.301002
PMCID:
PMC3293596
AbstractArticlePDF–1.1M
10.
Identification of mammalian arginyltransferases that modify a specific subset of protein substrates
Reena Rai, Anna Kashina
Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29): 10123–10128. Published online 2005 Jul 7. doi: 10.1073/pnas.0504500102
PMCID:
PMC1173364
AbstractArticlePDF–410K
11.
The final maturation state of β-actin involves N-terminal acetylation by NAA80, not N-terminal arginylation by ATE1
Adrian Drazic, Evy Timmerman, Ulrike Kajan, Michaёl Marie, Sylvia Varland, Francis Impens, Kris Gevaert, Thomas Arnesen
J Mol Biol. Author manuscript; available in PMC 2022 Dec 14.
Published in final edited form as: J Mol Biol. 2022 Jan 30; 434(2): 167397. Published online 2021 Dec 9. doi: 10.1016/j.jmb.2021.167397
PMCID:
PMC7613935
AbstractArticlePDF–1.7M
12.
Alternative Splicing Results in Differential Expression, Activity, and Localization of the Two Forms of Arginyl-tRNA-Protein Transferase, a Component of the N-End Rule Pathway
Yong Tae Kwon, Anna S. Kashina, Alexander Varshavsky
Mol Cell Biol. 1999 Jan; 19(1): 182–193. doi: 10.1128/mcb.19.1.182
PMCID:
PMC83877
AbstractArticlePDF–972K
13.
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress
Ah Jung Heo, Su Bin Kim, Chang Hoon Ji, Dohyun Han, Su Jin Lee, Su Hyun Lee, Min Ju Lee, Ji Su Lee, Aaron Ciechanover, Bo Yeon Kim, Yong Tae Kwon
Proc Natl Acad Sci U S A. 2021 Dec 14; 118(50): e2107993118. Published online 2021 Dec 10. doi: 10.1073/pnas.2107993118
PMCID:
PMC8685671
AbstractArticlePDF–3.1M
14.
Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling
Jang-Hyun Oh, Ju-Yeon Hyun, Shun-Jia Chen, Alexander Varshavsky
Proc Natl Acad Sci U S A. 2020 May 19; 117(20): 10778–10788. Published online 2020 May 4. doi: 10.1073/pnas.2003043117
PMCID:
PMC7245096
AbstractArticlePDF–1.7M
15.
FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex
Benita Sjögren, Steven Swaney, Richard R. Neubig
PLoS One. 2015; 10(5): e0123581. Published online 2015 May 13. doi: 10.1371/journal.pone.0123581
PMCID:
PMC4430315
AbstractArticlePDF–4.4M
16.
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome
Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A. Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsak
Front Mol Neurosci. 2019; 12: 224. Published online 2019 Sep 20. doi: 10.3389/fnmol.2019.00224
PMCID:
PMC6763791
AbstractArticlePDF–3.6M
17.
Mitochondrial Raf1 Regulates Glutamine Catabolism
Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari
Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297
PMCID:
PMC10942467
AbstractArticlePDF–6.5M
18.
A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing
David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Huettenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J.P. Mathy, Tina Perica, Kala B. Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A. Wankowicz, Markus Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C. O’Neal, Yiming Cai, Jason C.J.Chang, David J. Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu, Hao-Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A Verba, David A. Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, Danica G. Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Sali, Bryan L. Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Brian K. Shoichet, Nevan J. Krogan
Nature. Author manuscript; available in PMC 2020 Oct 30.
Published in final edited form as: Nature. 2020 Jul; 583(7816): 459–468. Published online 2020 Apr 30. doi: 10.1038/s41586-020-2286-9
PMCID:
PMC7431030
AbstractArticlePDF–7.7M
19.
A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease
Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate
Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851
PMCID:
PMC1380225
AbstractArticlePDF–329K
20.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M

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