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Select item 104917301.

VMHdm/c^SF-1 neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive

Takuya Yoshida, Mina Fujitani, Scotlynn Farmer, Ami Harada, Zhen Shi, Jenny J. Lee, Arely Tinajero, Ashish K. Singha, Teppei Fujikawa

Mol Metab. 2023 Nov; 77: 101792. Published online 2023 Aug 24. doi: 10.1016/j.molmet.2023.101792

PMCID:: PMC10491730

Abstract Article PDF–2.6M

Select item 104812962.

Region-specific sympatho-adrenergic regulation of specialized vasculature in bone homeostasis and regeneration

Hao-Kun Xu, Jie-Xi Liu, Chen-Xi Zheng, Lu Liu, Chao Ma, Jiong-Yi Tian, Yuan Yuan, Yuan Cao, Shu-Juan Xing, Si-Ying Liu, Qiang Li, Ya-Juan Zhao, Liang Kong, Yong-Jin Chen, Bing-Dong Sui

iScience. 2023 Sep 15; 26(9): 107455. Published online 2023 Jul 22. doi: 10.1016/j.isci.2023.107455

PMCID:: PMC10481296

Abstract Article PDF–7.8M

Select item 99757553.

Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense

Gabriel Komla Adzika, Richard Mprah, Ruqayya Rizvi, Adebayo Oluwafemi Adekunle, Marie Louise Ndzie Noah, Prosperl Ivette Wowui, Seyram Yao Adzraku, Joseph Adu-Amankwaah, Fengli Wang, Yuwen Lin, Lu Fu, Xiaomei Liu, Jie Xiang, Hong Sun

Front Immunol. 2023; 14: 1124649. Published online 2023 Feb 15. doi: 10.3389/fimmu.2023.1124649

PMCID:: PMC9975755

Abstract Article PDF–32M

Select item 93629154.

Adrenergic signaling controls early transcriptional programs during CD8⁺ T cell responses to viral infection

Leonardo D. Estrada, Didem Ağaç Çobanoğlu, Aaron Wise, Robert W. Maples, Murat Can Çobanoğlu, J. David Farrar

PLoS One. 2022; 17(8): e0272017. Published online 2022 Aug 9. doi: 10.1371/journal.pone.0272017

PMCID:: PMC9362915

Abstract Article PDF–2.1M

Select item 88163265.

Immune cell β₂-adrenergic receptors contribute to the development of heart failure

Miles A. Tanner, Charles A. Maitz, Laurel A. Grisanti

Am J Physiol Heart Circ Physiol. 2021 Oct 1; 321(4): H633–H649. Published online 2021 Aug 20. doi: 10.1152/ajpheart.00243.2021

PMCID:: PMC8816326

Abstract Article

Select item 87947066.

β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis

Gundula Rösch, Dominique Muschter, Shahed Taheri, Karima El Bagdadi, Christoph Dorn, Andrea Meurer, Frank Zaucke, Arndt F. Schilling, Susanne Grässel, Rainer H. Straub, Zsuzsa Jenei-Lanzl

Front Immunol. 2021; 12: 801505. Published online 2022 Jan 13. doi: 10.3389/fimmu.2021.801505

PMCID:: PMC8794706

Abstract Article PDF–16M

Select item 86722837.

Acetylcholine‐synthesizing macrophages in subcutaneous fat are regulated by β₂‐adrenergic signaling

Alexander J Knights, Shanshan Liu, Yingxu Ma, Victoria S Nudell, Eric Perkey, Matthew J Sorensen, Robert T Kennedy, Ivan Maillard, Li Ye, Heejin Jun, Jun Wu

EMBO J. 2021 Dec 15; 40(24): e106061. Published online 2021 Aug 30. doi: 10.15252/embj.2020106061

PMCID:: PMC8672283

Abstract Article PDF–1.5M

Select item 86014068.

β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME

Hemn Mohammadpour, Cameron R. MacDonald, Philip L. McCarthy, Scott I. Abrams, Elizabeth A. Repasky

Cell Rep. Author manuscript; available in PMC 2021 Nov 18.

Published in final edited form as: Cell Rep. 2021 Oct 26; 37(4): 109883. doi: 10.1016/j.celrep.2021.109883

PMCID:: PMC8601406

Abstract Article PDF–1.9M

Select item 85582469.

β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection

Stephane Koda, Beibei Zhang, Qian-Yang Zhou, Na Xu, Jing Li, Ji-Xin Liu, Man Liu, Zi-Yan Lv, Jian-Ling Wang, Yanbiao Shi, Sijia Gao, Qian Yu, Xiang-Yang Li, Yin-Hai Xu, Jia-Xu Chen, B. Oneill Telakeng Tekengne, Gabriel K. Adzika, Ren-Xian Tang, Hong Sun, Kui-Yang Zheng, Chao Yan

Front Immunol. 2021; 12: 754208. Published online 2021 Oct 18. doi: 10.3389/fimmu.2021.754208

PMCID:: PMC8558246

Abstract Article PDF–4.8M

Select item 715673110.

Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation

Minhui Chen, Guanxi Qiao, Bonnie L. Hylander, Hemn Mohammadpour, Xiang-Yang Wang, John R. Subjeck, Anurag K. Singh, Elizabeth A. Repasky

Nat Commun. 2020; 11: 1821. Published online 2020 Apr 14. doi: 10.1038/s41467-020-15676-0

PMCID:: PMC7156731

Abstract Article PDF–2.8M

Select item 687731611.

β2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells

Hemn Mohammadpour, Cameron R. MacDonald, Guanxi Qiao, Minhui Chen, Bowen Dong, Bonnie L. Hylander, Philip L. McCarthy, Scott I. Abrams, Elizabeth A. Repasky

J Clin Invest. 2019 Dec 2; 129(12): 5537–5552. Published online 2019 Nov 11. doi: 10.1172/JCI129502

PMCID:: PMC6877316

Abstract Article PDF–11M

Select item 670447612.

Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice

Atsuki Imaeda, Shota Tanaka, Kota Tonegawa, Shota Fuchigami, Yumi Igarashi, Misato Takahashi, Daichi Enomoto, Masanori Obana, Makiko Maeda, Miho Kihara, Hiroshi Kiyonari, Simon J. Conway, Yasushi Fujio, Hiroyuki Nakayama

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Aug 22.

Published in final edited form as: Biochem Biophys Res Commun. 2019 Feb 26; 510(1): 149–155. Published online 2019 Jan 23. doi: 10.1016/j.bbrc.2019.01.070

PMCID:: PMC6704476

Abstract Article PDF–1.8M

Select item 632696413.

β-Adrenergic signaling blocks murine CD8⁺ T-cell metabolic reprogramming during activation: a mechanism for immunosuppression by adrenergic stress

Guanxi Qiao, Mark J. Bucsek, Nicolette M. Winder, Minhui Chen, Thejaswini Giridharan, Scott H. Olejniczak, Bonnie L. Hylander, Elizabeth A. Repasky

Cancer Immunol Immunother. 2019 Jan; 68(1): 11–22. Published online 2018 Sep 18. doi: 10.1007/s00262-018-2243-8

PMCID:: PMC6326964

Abstract Article PDF–1.2M

Select item 584971714.

Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell

Ao Shen, Madeline Nieves-Cintron, Yawen Deng, Qian Shi, Dhrubajyoti Chowdhury, Jinyi Qi, Johannes W. Hell, Manuel F. Navedo, Yang K. Xiang

Nat Commun. 2018; 9: 1050. Published online 2018 Mar 13. doi: 10.1038/s41467-018-03459-7

PMCID:: PMC5849717

Abstract Article PDF–3.1M

Select item 581656315.

Beta-2 adrenergic receptors increase TREG cell suppression in an OVA-induced allergic asthma mouse model when mice are moderate aerobically exercised

Kari J. Dugger, Taylor Chrisman, Sarah L. Sayner, Parker Chastain, Kacie Watson, Robert Estes

BMC Immunol. 2018; 19: 9. Published online 2018 Feb 17. doi: 10.1186/s12865-018-0244-1

PMCID:: PMC5816563

Abstract Article PDF–1.3M

Select item 535044116.

High‐fat diet induces protein kinase A and G‐protein receptor kinase phosphorylation of β₂‐adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts

Qin Fu, Yuting Hu, Qingtong Wang, Yongming Liu, Ning Li, Bing Xu, Sungjin Kim, Nipavan Chiamvimonvat, Yang K. Xiang

J Physiol. 2017 Mar 15; 595(6): 1973–1986. Published online 2017 Feb 2. doi: 10.1113/JP273314

PMCID:: PMC5350441

Abstract Article PDF–988K

Select item 534699617.

Lack of β2-AR Increases Anxiety-Like Behaviors and Rewarding Properties of Cocaine

Huiwen Zhu, Zhiyuan Liu, Yiming Zhou, Xuming Yin, Bo Xu, Lan Ma, Xing Liu

Front Behav Neurosci. 2017; 11: 49. Published online 2017 Mar 13. doi: 10.3389/fnbeh.2017.00049

PMCID:: PMC5346996

Abstract Article PDF–1.8M

Select item 524104718.

Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8⁺ T-cell effector function

Leonardo D. Estrada, Didem Ağaç, J. David Farrar

Eur J Immunol. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Eur J Immunol. 2016 Aug; 46(8): 1948–1958. Published online 2016 Jun 8. doi: 10.1002/eji.201646395

PMCID:: PMC5241047

Abstract Article PDF–1.3M

Select item 512058719.

Leukocyte-Expressed β2-Adrenergic Receptors are Essential for Survival Following Acute Myocardial Injury

Laurel A. Grisanti, Anna M. Gumpert, Christopher J. Traynham, Joshua E. Gorsky, Ashley A. Repas, Erhe Gao, Rhonda L. Carter, Daohai Yu, John W. Calvert, Andrés Pun García, Borja Ibáñez, Joseph E. Rabinowitz, Walter J. Koch, Douglas G. Tilley

Circulation. Author manuscript; available in PMC 2017 Jul 12.

Published in final edited form as: Circulation. 2016 Jul 12; 134(2): 153–167. Published online 2016 Jun 30. doi: 10.1161/CIRCULATIONAHA.116.022304

PMCID:: PMC5120587

Abstract Article PDF–1.9M

Select item 511002420.

Adrenergic control of the adaptive immune response by diurnal lymphocyte recirculation through lymph nodes

Kazuhiro Suzuki, Yuki Hayano, Akiko Nakai, Fumika Furuta, Masaki Noda

J Exp Med. 2016 Nov 14; 213(12): 2567–2574. doi: 10.1084/jem.20160723

PMCID:: PMC5110024

Abstract Article PDF–2.0M

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