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Select item 55003261.

Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change

Mitchell S. Turker, Dmytro Grygoryev, Michael Lasarev, Anna Ohlrich, Furaha A. Rwatambuga, Sorrel Johnson, Cristian Dan, Bradley Eckelmann, Gwen Hryciw, Jian-Hua Mao, Antoine M. Snijders, Stacey Gauny, Amy Kronenberg

PLoS One. 2017; 12(7): e0180412. Published online 2017 Jul 6. doi: 10.1371/journal.pone.0180412

PMCID:: PMC5500326

Abstract Article PDF–5.5M

Select item 33892102.

Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress

Vamsi Rani, Carola A. Neumann, Changshun Shao, Jay A. Tischfield

Mutat Res. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Mutat Res. 2012 Jul 1; 735(1-2): 39–45. Published online 2012 May 11. doi: 10.1016/j.mrfmmm.2012.04.004

PMCID:: PMC3389210

Abstract Article PDF–1.3M

Select item 30794053.

Marked aneuploidy and loss of multiple chromosomes are common in autosomal mutants isolated from normal mouse kidney epithelium

Cristian Dan, Dymtro Grygoryev, Kelly Sandfort, Marissa Connolly, Brittany Cross, Michael Lasarev, Amy Kronenberg, Mitchell S. Turker

Genes Chromosomes Cancer. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: Genes Chromosomes Cancer. 2011 Apr; 50(4): 239–249. Published online 2011 Jan 19. doi: 10.1002/gcc.20849

PMCID:: PMC3079405

Abstract Article PDF–2.3M

Select item 30132944.

Aberrantly Silenced Promoters Retain a Persistent Memory of the Silenced State After Long-Term Reactivation

Jon A. Oyer, Phillip A. Yates, Sarah Godsey, Mitchell S. Turker

Mutat Res. Author manuscript; available in PMC 2012 Jan 10.

Published in final edited form as: Mutat Res. 2011 Jan 10; 706(1-2): 21–27. Published online 2010 Oct 28. doi: 10.1016/j.mrfmmm.2010.10.006

PMCID:: PMC3013294

Abstract Article PDF–1.2M

Select item 1648595.

Silencing of Mouse Aprt Is a Gradual Process in Differentiated Cells

Phillip A. Yates, Robert Burman, James Simpson, Olga N. Ponomoreva, Mathew J. Thayer, Mitchell S. Turker

Mol Cell Biol. 2003 Jul; 23(13): 4461–4470. doi: 10.1128/MCB.23.13.4461-4470.2003

PMCID:: PMC164859

Abstract Article PDF–184K

Select item 1479586.

The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation.

P Mummaneni, P Yates, J Simpson, J Rose, M S Turker

Nucleic Acids Res. 1998 Nov 15; 26(22): 5163–5169. doi: 10.1093/nar/26.22.5163

PMCID:: PMC147958

Abstract

Select item 1479427.

Determination of spontaneous loss of heterozygosity mutations in Aprt heterozygous mice.

P P Van Sloun, S W Wijnhoven, H J Kool, R Slater, G Weeda, A A van Zeeland, P H Lohman, H Vrieling

Nucleic Acids Res. 1998 Nov 1; 26(21): 4888–4894. doi: 10.1093/nar/26.21.4888

PMCID:: PMC147942

Summary PDF–113K

Select item 27674178.

Mutagenesis in vivo in T cells of p21-deficient mice

Changshun Shao, Li Liang, Xin Zhao, Yanping Chen, Betty Zheng, Jianmin Chen, Minjie Luo, Jay A. Tischfield

Mutat Res. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Mutat Res. 2009 Nov 2; 670(1-2): 103–106. Published online 2009 Sep 8. doi: 10.1016/j.mrfmmm.2009.09.001

PMCID:: PMC2767417

Abstract Article PDF–232K

Select item 24762109.

Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations

Julio Barrera-Oro, Tzu-Yang Liu, Erin Gorden, Raju Kucherlapati, Changshun Shao, Jay A Tischfield

Mutat Res. Author manuscript; available in PMC 2009 Jul 3.

Published in final edited form as: Mutat Res. 2008 Jul 3; 642(1-2): 74–79. Published online 2008 Apr 30. doi: 10.1016/j.mrfmmm.2008.04.006

PMCID:: PMC2476210

Abstract Article PDF–82K

Select item 39763910.

Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.

M K Dush, J M Sikela, S A Khan, J A Tischfield, P J Stambrook

Proc Natl Acad Sci U S A. 1985 May; 82(9): 2731–2735. doi: 10.1073/pnas.82.9.2731

PMCID:: PMC397639

Summary Page Browse PDF–1.0M

Select item 38792811.

Assignment of the Gene for Adenine Phosphoribosyltransferase to Human Chromosome 16 by Mouse-Human Somatic Cell Hybridization

Jay A. Tischfield, Frank H. Ruddle

Proc Natl Acad Sci U S A. 1974 Jan; 71(1): 45–49. doi: 10.1073/pnas.71.1.45

PMCID:: PMC387928

Summary Page Browse PDF–1.1M

Select item 3924112.

Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.

S J Engle, M G Stockelman, J Chen, G Boivin, M N Yum, P M Davies, M Y Ying, A Sahota, H A Simmonds, P J Stambrook, J A Tischfield

Proc Natl Acad Sci U S A. 1996 May 28; 93(11): 5307–5312. doi: 10.1073/pnas.93.11.5307

PMCID:: PMC39241

Summary Page Browse PDF–2.4M

Select item 1655813.

Chromosome instability contributes to loss of heterozygosity in mice lacking p53

Changshun Shao, Li Deng, Octavian Henegariu, Li Liang, Peter J. Stambrook, Jay A. Tischfield

Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13): 7405–7410. doi: 10.1073/pnas.97.13.7405

PMCID:: PMC16558

Abstract Article PDF–143K

Select item 488421114.

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

Berta N Vazquez, Joshua K Thackray, Nicolas G Simonet, Noriko Kane‐Goldsmith, Paloma Martinez‐Redondo, Trang Nguyen, Samuel Bunting, Alejandro Vaquero, Jay A Tischfield, Lourdes Serrano

EMBO J. 2016 Jul 15; 35(14): 1488–1503. Published online 2016 May 25. doi: 10.15252/embj.201593499

PMCID:: PMC4884211

Abstract Article PDF–2.8M

Select item 36930915.

Assignment of genes encoding metallothioneins I and II to Chinese hamster chromosome 3: evidence for the role of chromosome rearrangement in gene amplification.

R L Stallings, A C Munk, J L Longmire, C E Hildebrand, B D Crawford

Mol Cell Biol. 1984 Dec; 4(12): 2932–2936. doi: 10.1128/mcb.4.12.2932

PMCID:: PMC369309

Summary Page Browse PDF–1.1M

Select item 35993716.

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.

Y Kanno, C A Kozak, C Schindler, P H Driggers, D L Ennist, S L Gleason, J E Darnell, Jr, K Ozato

Mol Cell Biol. 1993 Jul; 13(7): 3951–3963. doi: 10.1128/mcb.13.7.3951

PMCID:: PMC359937

Summary Page Browse PDF–3.1M

Select item 32863117.

Genomic organization and chromosomal mapping of the mouse P-cadherin gene.

M Hatta, S Miyatani, N G Copeland, D J Gilbert, N A Jenkins, M Takeichi

Nucleic Acids Res. 1991 Aug 25; 19(16): 4437–4441. doi: 10.1093/nar/19.16.4437

PMCID:: PMC328631

Summary Page Browse PDF–920K

Select item 52164218.

Lsh, an epigenetic guardian of repetitive elements

Jiaqiang Huang, Tao Fan, Qingsheng Yan, Heming Zhu, Stephen Fox, Haleem J. Issaq, Lionel Best, Lisa Gangi, David Munroe, Kathrin Muegge

Nucleic Acids Res. 2004; 32(17): 5019–5028. Published online 2004 Sep 24. doi: 10.1093/nar/gkh821

PMCID:: PMC521642

Abstract Article PDF–326K

Select item 36027119.

Growth factor-induced delayed early response genes.

A Lanahan, J B Williams, L K Sanders, D Nathans

Mol Cell Biol. 1992 Sep; 12(9): 3919–3929. doi: 10.1128/mcb.12.9.3919

PMCID:: PMC360271

Summary Page Browse PDF–2.9M

Select item 293810020.

Interactome Mapping of the Phosphatidylinositol 3-Kinase-Mammalian Target of Rapamycin Pathway Identifies Deformed Epidermal Autoregulatory Factor-1 as a New Glycogen Synthase Kinase-3 Interactor

Fanny Pilot-Storck, Emilie Chopin, Jean-François Rual, Anais Baudot, Pavel Dobrokhotov, Marc Robinson-Rechavi, Christine Brun, Michael E. Cusick, David E. Hill, Laurent Schaeffer, Marc Vidal, Evelyne Goillot

Mol Cell Proteomics. 2010 Jul; 9(7): 1578–1593. Published online 2010 Apr 5. doi: 10.1074/mcp.M900568-MCP200