PMC Links for Gene (Select 11920) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 425

<< First< Prev

Page of 22

Select item 105997411.

Reduction of double-strand DNA break repair exacerbates vascular aging

Samuel I. Bloom, Jordan R. Tucker, Daniel R. Machin, Hossein Abdeahad, AdeLola O. Adeyemo, Tyler G. Thomas, R. Colton Bramwell, Lisa A. Lesniewski, Anthony J. Donato

Aging (Albany NY) 2023 Oct 15; 15(19): 9913–9947. Published online 2023 Oct 2. doi: 10.18632/aging.205066

PMCID:: PMC10599741

Abstract Article PDF–1.3M

Select item 93050772.

FATC domain deletion compromises ATM protein stability, lymphocyte development, and promotes lymphomagenesis

Maja Milanovic, Zhengping Shao, Verna M. Estes, Xiaobin S. Wang, Demis Menolfi, Xiaohui Lin, Brian J. Lee, Jun Xu, Olivia M. Cupo, Dong Wang, Shan Zha

J Immunol. Author manuscript; available in PMC 2022 Jul 22.

Published in final edited form as: J Immunol. 2021 Mar 15; 206(6): 1228–1239. Published online 2021 Feb 3. doi: 10.4049/jimmunol.2000967

PMCID:: PMC9305077

Abstract Article PDF–3.8M

Select item 85801483.

DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response

Xuan Song, Jacqueline T. M. Aw, Fulin Ma, Ming Fung Cheung, Danny Leung, Karl Herrup

J Neurosci. 2021 Nov 10; 41(45): 9286–9307. doi: 10.1523/JNEUROSCI.0845-21.2021

PMCID:: PMC8580148

Abstract Article PDF–8.8M

Select item 82893544.

Deficiency of ataxia-telangiectasia mutated kinase modulates functional and biochemical parameters of the heart in response to Western-type diet

Mary C. Wingard, Suman Dalal, Paige L. Shook, Rachel Myers, Barbara A. Connelly, Douglas P. Thewke, Mahipal Singh, Krishna Singh

Am J Physiol Heart Circ Physiol. 2021 Jun 1; 320(6): H2324–H2338. Published online 2021 Apr 30. doi: 10.1152/ajpheart.00990.2020

PMCID:: PMC8289354

Abstract Article

Select item 82762635.

Survival and Functional Immune Reconstitution After Haploidentical Stem Cell Transplantation in Atm-Deficient Mice

Ruth Pia Duecker, Lucia Gronau, Patrick C. Baer, Stefan Zielen, Ralf Schubert

Front Immunol. 2021; 12: 693897. Published online 2021 Jun 29. doi: 10.3389/fimmu.2021.693897

PMCID:: PMC8276263

Abstract Article PDF–5.4M

Select item 80459116.

NAD⁺ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

Beimeng Yang, Xiuli Dan, Yujun Hou, Jong‐Hyuk Lee, Noah Wechter, Sudarshan Krishnamurthy, Risako Kimura, Mansi Babbar, Tyler Demarest, Ross McDevitt, Shiliang Zhang, Yongqing Zhang, Mark P. Mattson, Deborah L. Croteau, Vilhelm A. Bohr

Aging Cell. 2021 Apr; 20(4): e13329. Published online 2021 Mar 18. doi: 10.1111/acel.13329

PMCID:: PMC8045911

Abstract Article PDF–2.5M

Select item 79859687.

Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype

Efrat Tal, Marina Alfo, Shan Zha, Ari Barzilai, Chris I. De Zeeuw, Yael Ziv, Yosef Shiloh

DNA Repair (Amst) Author manuscript; available in PMC 2021 Mar 23.

Published in final edited form as: DNA Repair (Amst). 2018 Dec; 72: 10–17. Published online 2018 Oct 11. doi: 10.1016/j.dnarep.2018.10.001

PMCID:: PMC7985968

Abstract Article PDF–1.6M

Select item 78959528.

Elevated inflammatory responses and targeted therapeutic intervention in a preclinical mouse model of ataxia-telangiectasia lung disease

Rudel A. Saunders, Thomas F. Michniacki, Courtney Hames, Hilary A. Moale, Carol Wilke, Molly E. Kuo, Johnathan Nguyen, Andrea J. Hartlerode, Bethany B. Moore, JoAnn M. Sekiguchi

Sci Rep. 2021; 11: 4268. Published online 2021 Feb 19. doi: 10.1038/s41598-021-83531-3

PMCID:: PMC7895952

Abstract Article PDF–1.1M

Select item 77733669.

Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models

Katherine Deland, Bryce F. Starr, Joshua S. Mercer, Jovita Byemerwa, Donna M. Crabtree, Nerissa T. Williams, Lixia Luo, Yan Ma, Mark Chen, Oren J. Becher, David G. Kirsch

J Clin Invest. 2021 Jan 4; 131(1): e142158. Published online 2021 Jan 4. doi: 10.1172/JCI142158

PMCID:: PMC7773366

Abstract Article PDF–1.0M

Select item 689297410.

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

Ruth Duecker, Patrick C. Baer, Aileen Buecker, Sabine Huenecke, Lisa-Marie Pfeffermann, Ute Modlich, Shahrzad Bakhtiar, Peter Bader, Stefan Zielen, Ralf Schubert

Front Immunol. 2019; 10: 2785. Published online 2019 Nov 27. doi: 10.3389/fimmu.2019.02785

PMCID:: PMC6892974

Abstract Article PDF–1.0M

Select item 674050911.

Oxidative Stress Is Responsible for Deficient Survival and Dendritogenesis in Purkinje Neurons from Ataxia-Telangiectasia Mutated Mutant Mice

Philip Chen, Cheng Peng, John Luff, Kevin Spring, Dianne Watters, Steven Bottle, Shigeki Furuya, Martin F. Lavin

J Neurosci. 2003 Dec 10; 23(36): 11453–11460. doi: 10.1523/JNEUROSCI.23-36-11453.2003

PMCID:: PMC6740509

Abstract Article PDF–309K

Select item 672517212.

Loss of Neuronal Cell Cycle Control in Ataxia-Telangiectasia: A Unified Disease Mechanism

Yan Yang, Karl Herrup

J Neurosci. 2005 Mar 9; 25(10): 2522–2529. doi: 10.1523/JNEUROSCI.4946-04.2005

PMCID:: PMC6725172

Abstract Article PDF–704K

Select item 668789513.

Accumulation of Cytoplasmic DNA Due to ATM Deficiency Activates the Microglial Viral Response System with Neurotoxic Consequences

Xuan Song, Fulin Ma, Karl Herrup

J Neurosci. 2019 Aug 7; 39(32): 6378–6394. doi: 10.1523/JNEUROSCI.0774-19.2019

PMCID:: PMC6687895

Abstract Article PDF–6.1M

Select item 652928014.

ATM influences germinal center integrity

Laura Nicolas, Montserrat Cols, Ryan Smolkin, Keith C Fernandez, William T. Yewdell, Wei-Feng Yen, Shan Zha, Bao Q Vuong, Jayanta Chaudhuri

J Immunol. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: J Immunol. 2019 Jun 1; 202(11): 3137–3142. Published online 2019 Apr 26. doi: 10.4049/jimmunol.1801033

PMCID:: PMC6529280

Abstract Article PDF–1.9M

Select item 619833515.

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes

Elad Horwitz, Lars Krogvold, Sophia Zhitomirsky, Avital Swisa, Maya Fischman, Tsuria Lax, Tehila Dahan, Noa Hurvitz, Noa Weinberg-Corem, Agnes Klochendler, Alvin C. Powers, Marcela Brissova, Anne Jörns, Sigurd Lenzen, Benjamin Glaser, Knut Dahl-Jørgensen, Yuval Dor

Diabetes. 2018 Nov; 67(11): 2305–2318. Published online 2018 Aug 27. doi: 10.2337/db17-1006

PMCID:: PMC6198335

Abstract Article PDF–2.1M

Select item 611309316.

Global metabolomic responses in urine from Atm deficient mice in response to LD_50/30 gamma irradiation doses

Evagelia C Laiakis, Tytus D Mak, Steven J Strawn, Yi-Wen Wang, Bo-Hyun Moon, Pelagie Ake, Albert J Fornace, Jr

Environ Mol Mutagen. Author manuscript; available in PMC 2019 Aug 10.

Published in final edited form as: Environ Mol Mutagen. 2018 Aug; 59(7): 576–585. Published online 2018 Aug 10. doi: 10.1002/em.22202

PMCID:: PMC6113093

Abstract Article PDF–967K

Select item 608778117.

Ataxia telangiectasia mutated kinase deficiency impairs the autophagic response early during myocardial infarction

Patsy R. Thrasher, Stephanie L. C. Scofield, Suman Dalal, Claire C. Crawford, Mahipal Singh, Krishna Singh

Am J Physiol Heart Circ Physiol. 2018 Jul 1; 315(1): H48–H57. Published online 2018 Apr 13. doi: 10.1152/ajpheart.00042.2018

PMCID:: PMC6087781

Abstract Article

Select item 607771318.

Astrocytes restore connectivity and synchronization in dysfunctional cerebellar networks

Sivan Kanner, Miri Goldin, Ronit Galron, Eshel Ben Jacob, Paolo Bonifazi, Ari Barzilai

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 8025–8030. Published online 2018 Jul 16. doi: 10.1073/pnas.1718582115

PMCID:: PMC6077713

Abstract Article PDF–1.6M

Select item 606767519.

Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage

Paula Gutierrez-Martinez, Leah Hogdal, Manavi Nagai, Miriama Kruta, Rumani Singh, Kristopher Sarosiek, Andre Nussenzweig, Isabel Beerman, Anthony Letai, Derrick J. Rossi

Nat Cell Biol. Author manuscript; available in PMC 2018 Sep 12.

Published in final edited form as: Nat Cell Biol. 2018 Apr; 20(4): 413–421. Published online 2018 Mar 12. doi: 10.1038/s41556-018-0054-y

PMCID:: PMC6067675

Abstract Article PDF–1.0M

Select item 558632320.

Haplodeficiency of Ataxia Telangiectasia Mutated Accelerates Heart Failure After Myocardial Infarction

Lixin Jia, Wenmei Zhang, Youcai Ma, Boya Chen, Yan Liu, Chunmei Piao, Yuan Wang, Min Yang, Tingting Liu, Junmeng Zhang, Taotao Li, Shaoping Nie, Jie Du

J Am Heart Assoc. 2017 Jul; 6(7): e006349. Published online 2017 Jul 19. doi: 10.1161/JAHA.117.006349