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Select item 50420151.

Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma

Soon Young Park, Yuji Piao, Craig Thomas, Gregory N. Fuller, John F. de Groot

Oncotarget. 2016 May 3; 7(18): 26793–26805. Published online 2016 Mar 30. doi: 10.18632/oncotarget.8471

PMCID:: PMC5042015

Abstract Article PDF–6.0M

Select item 13775032.

Homozygosity mapping of a gene responsible for gelatinous drop-like corneal dystrophy to chromosome 1p.

M Tsujikawa, H Kurahashi, T Tanaka, M Okada, S Yamamoto, N Maeda, H Watanabe, Y Inoue, A Kiridoshi, K Matsumoto, Y Ohashi, S Kinoshita, Y Shimomura, Y Nakamura, Y Tano

Am J Hum Genet. 1998 Oct; 63(4): 1073–1077. doi: 10.1086/302071

PMCID:: PMC1377503

Abstract

Select item 31489773.

Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy

Raymond Wong, Ahalya Balachandran, Annie YQ Mao, Wendy Dobson, Scott Gray-Owen, Alan Cochrane

Retrovirology. 2011; 8: 47. Published online 2011 Jun 17. doi: 10.1186/1742-4690-8-47

PMCID:: PMC3148977

Abstract Article PDF–3.6M

Select item 31977134.

Differential expression of 24,426 human alternative splicing events and predicted cis-regulation in 48 tissues and cell lines

John C. Castle, Chaolin Zhang, Jyoti K. Shah, Amit V. Kulkarni, Thomas A. Cooper, Jason M. Johnson

Nat Genet. Author manuscript; available in PMC 2011 Oct 20.

Published in final edited form as: Nat Genet. 2008 Dec; 40(12): 1416–1425. Published online 2008 Nov 2. doi: 10.1038/ng.264

PMCID:: PMC3197713

Abstract Article PDF–2.8M

Select item 77161495.

Depletion of CLK2 sensitizes glioma stem-like cells to PI3K/mTOR and FGFR inhibitors

Soon Young Park, Sandeep Mittal, Jianwen Dong, Kangjin Jeong, Emmanuel Martinez-Ledesma, Yuji Piao, Sabbir Khan, Verlene Henry, Roel GW Verhaak, Nazanin Majd, Veerakumar Balasubramaniyan, John F de Groot

Am J Cancer Res. 2020; 10(11): 3765–3783. Published online 2020 Nov 1.

PMCID:: PMC7716149

Abstract Article PDF–6.1M

Select item 48555336.

Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint

Eleni Petsalaki, George Zachos

Nat Commun. 2016; 7: 11451. Published online 2016 Apr 29. doi: 10.1038/ncomms11451

PMCID:: PMC4855533

Abstract Article PDF–4.1M

Select item 29511897.

Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation

Seon Young Nam, Hyung Ho Seo, Hyung Sun Park, Sungkwan An, Ji-Young Kim, Kwang Hee Yang, Cha Soon Kim, Meeseon Jeong, Young-Woo Jin

J Biol Chem. 2010 Oct 8; 285(41): 31157–31163. Published online 2010 Aug 3. doi: 10.1074/jbc.M110.122044

PMCID:: PMC2951189

Abstract Article PDF–1.3M

Select item 53800518.

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

Prakash Kulkarni, Mohit Kumar Jolly, Dongya Jia, Steven M. Mooney, Ajay Bhargava, Luciane T. Kagohara, Yihong Chen, Pengyu Hao, Yanan He, Robert W. Veltri, Alexander Grishaev, Keith Weninger, Herbert Levine, John Orban

Proc Natl Acad Sci U S A. 2017 Mar 28; 114(13): E2644–E2653. Published online 2017 Mar 13. doi: 10.1073/pnas.1700082114

PMCID:: PMC5380051

Abstract Article PDF–1.7M

Select item 20490399.

Phosphorylation of CK1δ: identification of Ser³⁷⁰ as the major phosphorylation site targeted by PKA in vitro and in vivo

Georgios Giamas, Heidrun Hirner, Levani Shoshiashvili, Arnhild Grothey, Susanne Gessert, Michael Kühl, Doris Henne-Bruns, Constantinos E. Vorgias, Uwe Knippschild

Biochem J. 2007 Sep 15; 406(Pt 3): 389–398. Prepublished online 2007 Jun 27. Published online 2007 Aug 29. doi: 10.1042/BJ20070091

Correction in:: Biochem J. 2019 Apr 18; 476(8): 1221–1225.

PMCID:: PMC2049039

Abstract Article PDF–607K

Select item 31067410.

Identification of Three Additional Genes Contiguous to the Glucocerebrosidase Locus on Chromosome 1q21: Implications for Gaucher Disease

Suzanne L. Winfield, Nahid Tayebi, Brian M. Martin, Edward I. Ginns, Ellen Sidransky

Genome Res. 1997 Oct; 7(10): 1020–1026. doi: 10.1101/gr.7.10.1020

PMCID:: PMC310674

Abstract Article PDF–593K

Select item 268287911.

Heterogeneous Nuclear Ribonucleoprotein G Regulates Splice Site Selection by Binding to CC(A/C)-rich Regions in Pre-mRNA

Bettina Heinrich, Zhaiyi Zhang, Oleg Raitskin, Michael Hiller, Natalya Benderska, Annette M. Hartmann, Laurent Bracco, David Elliott, Shani Ben-Ari, Hermona Soreq, Joseph Sperling, Ruth Sperling, Stefan Stamm

J Biol Chem. 2009 May 22; 284(21): 14303–14315. doi: 10.1074/jbc.M901026200

PMCID:: PMC2682879

Abstract Article PDF–924K

Select item 821016212.

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells

Muhammad Sohail, Lulzim Shkreta, Johanne Toutant, Safwat Rabea, Jean-Philippe Babeu, Caroline Huard, Jasmin Coulombe-Huntington, Aurélie Delannoy, Morgane Placet, Sameh Geha, Fernand-Pierre Gendron, François Boudreau, Mike Tyers, David S Grierson, Benoit Chabot

NAR Cancer. 2021 Jun; 3(2): zcab019. Published online 2021 May 25. doi: 10.1093/narcan/zcab019

PMCID:: PMC8210162

Abstract Article PDF–5.8M

Select item 39575213.

An unappreciated role for RNA surveillance

R Tyler Hillman, Richard E Green, Steven E Brenner

Genome Biol. 2004; 5(2): R8. Published online 2004 Feb 2. doi: 10.1186/gb-2004-5-2-r8

PMCID:: PMC395752

Abstract Article PDF–378K

Select item 419794714.

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage

Sarah J. Hill, Thomas Rolland, Guillaume Adelmant, Xianfang Xia, Matthew S. Owen, Amélie Dricot, Travis I. Zack, Nidhi Sahni, Yves Jacob, Tong Hao, Kristine M. McKinney, Allison P. Clark, Deepak Reyon, Shengdar Q. Tsai, J. Keith Joung, Rameen Beroukhim, Jarrod A. Marto, Marc Vidal, Suzanne Gaudet, David E. Hill, David M. Livingston

Genes Dev. 2014 Sep 1; 28(17): 1957–1975. doi: 10.1101/gad.241620.114

PMCID:: PMC4197947

Abstract Article PDF–2.4M

Select item 689239315.

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2019 Dec 4.

Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008

PMCID:: PMC6892393

Abstract Article PDF–1.7M

Select item 660120816.

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

Manal Alsulami, Nayla Munawar, Eugene Dillon, Giorgio Oliviero, Kieran Wynne, Mona Alsolami, Catherine Moss, Peadar Ó Gaora, Fergal O'Meara, David Cotter, Gerard Cagney

Mol Cell Proteomics. 2019 Jul; 18(7): 1428–1436. Published online 2019 May 10. doi: 10.1074/mcp.RA119.001518

PMCID:: PMC6601208

Abstract Article PDF–1.8M

Select item 584026617.

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez

Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9

PMCID:: PMC5840266

Abstract Article PDF–2.9M

Select item 389478618.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Abstract Article PDF–5.0M

Select item 509804219.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

Select item 340884720.

Interpreting cancer genomes using systematic host perturbations by tumour virus proteins

Orit Rozenblatt-Rosen, Rahul C. Deo, Megha Padi, Guillaume Adelmant, Michael A. Calderwood, Thomas Rolland, Miranda Grace, Amélie Dricot, Manor Askenazi, Maria Tavares, Sam Pevzner, Fieda Abderazzaq, Danielle Byrdsong, Anne-Ruxandra Carvunis, Alyce A. Chen, Jingwei Cheng, Mick Correll, Melissa Duarte, Changyu Fan, Mariet C. Feltkamp, Scott B. Ficarro, Rachel Franchi, Brijesh K. Garg, Natali Gulbahce, Tong Hao, Amy M. Holthaus, Robert James, Anna Korkhin, Larisa Litovchick, Jessica C. Mar, Theodore R. Pak, Sabrina Rabello, Renee Rubio, Yun Shen, Saurav Singh, Jennifer M. Spangle, Murat Tasan, Shelly Wanamaker, James T. Webber, Jennifer Roecklein-Canfield, Eric Johannsen, Albert-László Barabási, Rameen Beroukhim, Elliott Kieff, Michael E. Cusick, David E. Hill, Karl Münger, Jarrod A. Marto, John Quackenbush, Frederick P. Roth, James A. DeCaprio, Marc Vidal

Nature. Author manuscript; available in PMC 2013 Jan 26.

Published in final edited form as: Nature. 2012 Jul 26; 487(7408): 491–495. doi: 10.1038/nature11288

PMCID:: PMC3408847

Abstract Article PDF–937K

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