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Select item 111596041.

mRNA expression level of estrogen‐inducible gene, α1‐antichymotrypsin, is a predictor of early tumor recurrence in patients with invasive breast cancers

Jun Yamamura, Yasuo Miyoshi, Yasuhiro Tamaki, Tetsuya Taguchi, Kyoko Iwao, Morito Monden, Kikuya Kato, Shinzaburo Noguchi

Cancer Sci. 2004 Nov; 95(11): 887–892. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb02198.x

PMCID:: PMC11159604

Abstract Article PDF–183K

Select item 109164182.

SERPINA3: A novel inflammatory biomarker associated with cerebral small vessel disease burden in ischemic stroke

Xiao Hu, Zhong‐Song Xiao, Yi‐Qing Shen, Wen‐Song Yang, Peng Wang, Pei‐Zheng Li, Zi‐Jie Wang, Ming‐Jun Pu, Li‐Bo Zhao, Peng Xie, Qi Li

CNS Neurosci Ther. 2024 Mar; 30(3): e14472. Published online 2023 Sep 18. doi: 10.1111/cns.14472

PMCID:: PMC10916418

Abstract Article PDF–1.2M

Select item 105527213.

Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF-κB in lung cancer

Yanxia Jin, Yueyang Zhang, Ankang Huang, Ying Chen, Jinsong Wang, Na Liu, Xianping Wang, Yongsheng Gong, Weidong Wang, Jicheng Pan

Int J Oncol. 2023 Aug; 63(2): 96. Published online 2023 Jul 5. doi: 10.3892/ijo.2023.5544

PMCID:: PMC10552721

Abstract Article PDF–6.5M

Select item 95929164.

Zuyan Fan, Yan Gao, Nan Jiang, Fengxia Zhang, Shuangxin Liu, Quhuan Li

Front Immunol. 2022; 13: 979995. Published online 2022 Oct 11. doi: 10.3389/fimmu.2022.979995

PMCID:: PMC9592916

Abstract Article PDF–49M

Select item 87128105.

Circulating SERPINA3 improves prognostic stratification in patients with a de novo or worsened heart failure

Leen Delrue, Marc Vanderheyden, Monika Beles, Pasquale Paolisso, Giuseppe Di Gioia, Riet Dierckx, Sofie Verstreken, Marc Goethals, Ward Heggermont, Jozef Bartunek

ESC Heart Fail. 2021 Dec; 8(6): 4780–4790. Published online 2021 Nov 1. doi: 10.1002/ehf2.13659

PMCID:: PMC8712810

Abstract Article PDF–3.1M

Select item 86428986.

CircSERPINA3 regulates SERPINA3-mediated apoptosis, autophagy and aerobic glycolysis of prostate cancer cells by competitively binding to MiR-653-5p and recruiting BUD13

Zengshu Xing, Sailian Li, Zhenxiang Liu, Chong Zhang, Zhiming Bai

J Transl Med. 2021; 19: 492. Published online 2021 Dec 3. doi: 10.1186/s12967-021-03063-2

PMCID:: PMC8642898

Abstract Article PDF–4.0M

Select item 85893547.

Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma

Qing Yuan, Song‐Quan Wang, Guang‐Tao Zhang, Jie He, Zhi‐Dan Liu, Ming‐Rong Wang, Hong‐Qing Cai, Jing‐Hai Wan

Immun Inflamm Dis. 2021 Dec; 9(4): 1618–1630. Published online 2021 Aug 27. doi: 10.1002/iid3.515

PMCID:: PMC8589354

Abstract Article PDF–3.8M

Select item 82136668.

Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells

Yingzi Zhang, Jiao Tian, Chi Qu, Yang Peng, Jinwei Lei, Kang Li, Beige Zong, Lu Sun, Shengchun Liu

Breast Cancer. 2021; 28(4): 859–873. Published online 2021 Feb 10. doi: 10.1007/s12282-021-01221-4

PMCID:: PMC8213666

Abstract Article PDF–4.5M

Select item 81059049.

CSF SERPINA3 Levels Are Elevated in Patients With Progressive MS

Nicolás Fissolo, Clara Matute-Blanch, Mohamoud Osman, Carme Costa, Rucsanda Pinteac, Berta Miró, Alex Sanchez, Verónica Brito, Irena Dujmovic, Margarete Voortman, Michael Khalil, Eva Borràs, Eduard Sabidó, Shohreh Issazadeh-Navikas, Xavier Montalban, Manuel Comabella Lopez

Neurol Neuroimmunol Neuroinflamm. 2021 Mar; 8(2): e941. Published online 2021 Jan 12. doi: 10.1212/NXI.0000000000000941

Correction in:: Neurol Neuroimmunol Neuroinflamm. 2021 May; 8(3): e983.

PMCID:: PMC8105904

Abstract Article PDF–1.2M

Select item 804134510.

Alpha 1-antichymotrypsin contributes to stem cell characteristics and enhances tumorigenicity of glioblastoma

Montserrat Lara-Velazquez, Natanael Zarco, Anna Carrano, Jordan Phillipps, Emily S Norton, Paula Schiapparelli, Rawan Al-kharboosh, Jordina Rincon-Torroella, Stephanie Jeanneret, Teresa Corona, Jose Segovia, Mark E Jentoft, Kaisorn L Chaichana, Yan W Asmann, Alfredo Quiñones-Hinojosa, Hugo Guerrero-Cazares

Neuro Oncol. 2021 Apr; 23(4): 599–610. Published online 2020 Nov 29. doi: 10.1093/neuonc/noaa264

PMCID:: PMC8041345

Abstract Article PDF–2.5M

Select item 784065711.

Glycoproteoform Profiles of Individual Patients’ Plasma Alpha-1-Antichymotrypsin are Unique and Extensively Remodeled Following a Septic Episode

Tomislav Čaval, Yu-Hsien Lin, Meri Varkila, Karli R. Reiding, Marc J. M. Bonten, Olaf L. Cremer, Vojtech Franc, Albert J. R. Heck

Front Immunol. 2020; 11: 608466. Published online 2021 Jan 14. doi: 10.3389/fimmu.2020.608466

PMCID:: PMC7840657

Abstract Article PDF–2.7M

Select item 538664112.

Up-regulation of SERPINA3 correlates with high mortality of melanoma patients and increased migration and invasion of cancer cells

Jiaying Zhou, Yabin Cheng, Liren Tang, Magdalena Martinka, Sunil Kalia

Oncotarget. 2017 Mar 21; 8(12): 18712–18725. Published online 2016 May 17. doi: 10.18632/oncotarget.9409

PMCID:: PMC5386641

Abstract Article PDF–4.7M

Select item 452042013.

Is Alpha-1 Antichymotrypsin Gene Polymorphism a Risk Factor for Primary Intracerebral Hemorrhage? A Case-Control Study and Meta-Analysis

Xin Hu, Yunke Li, Hao Li, Yuan Fang, Ming Liu, Chao You

Med Sci Monit. 2015; 21: 2149–2155. Published online 2015 Jul 24. doi: 10.12659/MSM.894365

PMCID:: PMC4520420

Abstract Article PDF–370K

Select item 401421514.

SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis

Guang-Dong Yang, Xiao-Mei Yang, Huan Lu, Yuan Ren, Ming-Ze Ma, Lin-Yan Zhu, Jing-Hao Wang, Wei-Wei Song, Wen-Ming Zhang, Rong Zhang, Zhi-Gang Zhang

Int J Clin Exp Pathol. 2014; 7(4): 1348–1358. Published online 2014 Mar 15.

PMCID:: PMC4014215

Abstract Article PDF–1.0M

Select item 160996315.

Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer’s disease

M. Ilyas Kamboh, Ryan L. Minster, Margaret Kenney, Ayla Ozturk, Purnima P. Desai, Candace M. Kammerer, Steven T. DeKosky

Neurobiol Aging. Author manuscript; available in PMC 2007 Oct 1.

Published in final edited form as: Neurobiol Aging. 2006 Oct; 27(10): 1435–1439. Published online 2005 Aug 30. doi: 10.1016/j.neurobiolaging.2005.07.015

PMCID:: PMC1609963

Abstract Article PDF–386K

Select item 105050216.

Cloning of the human alpha 1 antichymotrypsin gene and genetic analysis of the gene in relation to alpha 1 antitrypsin deficiency.

G D Kelsey, D Abeliovich, C J McMahon, D Whitehouse, G Corney, S Povey, D A Hopkinson, J Wolfe, G Mieli-Vergani, A P Mowat

J Med Genet. 1988 Jun; 25(6): 361–368. doi: 10.1136/jmg.25.6.361

PMCID:: PMC1050502

Summary Page Browse PDF–1.1M

Select item 2661717.

Inactive conformation of the serpin α₁-antichymotrypsin indicates two-stage insertion of the reactive loop: Implications for inhibitory function and conformational disease

Bibek Gooptu, Bart Hazes, Wun-Shaing W. Chang, Timothy R. Dafforn, Robin W. Carrell, Randy J. Read, David A. Lomas

Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1): 67–72. doi: 10.1073/pnas.97.1.67

PMCID:: PMC26617

Abstract Article PDF–502K

Select item 914829718.

Serpin Signatures in Prion and Alzheimer’s Diseases

Marco Zattoni, Marika Mearelli, Silvia Vanni, Arianna Colini Baldeschi, Thanh Hoa Tran, Chiara Ferracin, Marcella Catania, Fabio Moda, Giuseppe Di Fede, Giorgio Giaccone, Fabrizio Tagliavini, Gianluigi Zanusso, James W. Ironside, Isidre Ferrer, Giuseppe Legname

Mol Neurobiol. 2022; 59(6): 3778–3799. Published online 2022 Apr 13. doi: 10.1007/s12035-022-02817-3

PMCID:: PMC9148297

Abstract Article PDF–3.0M

Select item 652977419.

SERPINA3 is a key modulator of HNRNP-K transcriptional activity against oxidative stress in HCC

Eunkyong Ko, Jong-Seo Kim, Jong Woo Bae, Jeesoo Kim, Sung-Gyoo Park, Guhung Jung

Redox Biol. 2019 Jun; 24: 101217. Published online 2019 May 12. doi: 10.1016/j.redox.2019.101217

PMCID:: PMC6529774

Abstract Article PDF–4.0M

Select item 568813920.

Differential overexpression of SERPINA3 in human prion diseases

S. Vanni, F. Moda, M. Zattoni, E. Bistaffa, E. De Cecco, M. Rossi, G. Giaccone, F. Tagliavini, S. Haïk, J. P. Deslys, G. Zanusso, J. W. Ironside, I. Ferrer, G. G. Kovacs, G. Legname

Sci Rep. 2017; 7: 15637. Published online 2017 Nov 15. doi: 10.1038/s41598-017-15778-8